在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RPS6KB2 Antibody

RPS6KB2 Antibody

  • 中文名稱：
    RPS6KB2兔多克隆抗體
  • 貨號：
    CSB-PA02905A0Rb
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: RPS6KB2 antibody at 2µg/ml
      Lane 1: EC109 whole cell lysate
      Lane 2: 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/15000 dilution
      Predicted band size: 54, 17 kDa
      Observed band size: 54 kDa
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA02905A0Rb at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RPS6KB2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    70 kDa ribosomal protein S6 kinase 2 antibody; EC 2.7.11.1 antibody; KS6B2_HUMAN antibody; p70 beta antibody; p70 ribosomal S6 kinase beta antibody; p70 S6 kinase beta antibody; p70 S6K-beta antibody; p70 S6KB antibody; p70 S6Kbeta antibody; p70(S6K) beta antibody; p70-beta antibody; p70-S6K 2 antibody; P70S6K2 antibody; p70S6Kb antibody; Ribosomal protein S6 kinase 70kDa; polypeptide 2 antibody; Ribosomal protein S6 kinase B2 antibody; Ribosomal protein S6 kinase beta 2 antibody; Ribosomal protein S6 kinase beta-2 antibody; Rps6kb2 antibody; S6 kinase related kinase antibody; S6 kinase-related kinase antibody; S6K beta 2 antibody; S6K beta antibody; S6K-beta antibody; S6K-beta-2 antibody; S6K2 antibody; Serine/threonine protein kinase 14 beta antibody; Serine/threonine-protein kinase 14B antibody; SRK antibody; STK14B antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Ribosomal protein S6 kinase beta-2 protein (1-210AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，RPS6KB2 Antibody (CSB-PA02905A0Rb)，的標記方式是Non-conjugated。對于RPS6KB2 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA02905B0Rb RPS6KB2 Antibody, HRP conjugated ELISA
    FITC CSB-PA02905C0Rb RPS6KB2 Antibody, FITC conjugated
    Biotin CSB-PA02905D0Rb RPS6KB2 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Phosphorylates specifically ribosomal protein S6. Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7.
  • 基因功能參考文獻：
    1. Overexpression of catalytically-active Akt or knockdown of glycogen synthase kinase-3 (GSK3)-beta, a substrate for Akt, had little effect on Mcl-1 downregulation caused by S6K2 deficiency PMID: 28301598
    2. We propose that the S6K2/TRBP node controls miRNA biogenesis in HDLECs and provides a molecular link between the mTOR pathway and the miRNA biogenesis machinery. PMID: 27407113
    3. discovered that ERBB4 and S6K2 were the direct targets of miR-193a-3p and that PIK3R3 and mTOR were the direct targets of miR-193a-5p in non-small-cell lung cancer PMID: 24469061
    4. Degradation of Tiam1 by casein kinase 1 and the SCFbetaTrCP ubiquitin ligase controls the duration of mTOR-S6K signaling. PMID: 25124033
    5. The mTOR effectors 4EBP1 and S6K2 are frequently coexpressed, and associated with a poor prognosis and endocrine resistance in breast cancer. PMID: 24131622
    6. The p85 S6K1 promotes H2O2-induced cell death via a rapamycin-insensitive mechanism. PMID: 22955948
    7. S6K2 amplification was frequently observed in gastric cancer and was related to a poor prognosis PMID: 23393338
    8. Study shows that the two homologues of S6K have distinct effects on Akt activation and cell survivalin breast cancer. PMID: 21427355
    9. heterogeneous ribonucleoprotein F is involved in the regulation of cell proliferation via the mammalian target of rapamycin/S6 kinase 2 pathway PMID: 20308064
    10. p70 S6 kinase regulates neutrophilic differentiation in HL-60 cells PMID: 12176053
    11. regulation of nucleocytoplasmic shuttling of S6KbetaII by protein kinase C-mediated phosphorylation PMID: 12529391
    12. the PI3K/p70 S6K/c-Myc cascade plays an important role in neutrophilic proliferation in HL-60 cells. PMID: 12818373
    13. These data suggest that activated p70 S6 kinase could mediate an up-regulation of tau translation. PMID: 12875979
    14. p70 ribosomal protein S6 kinase activity was induced by K-Ras in a phosphatidylinositol 3-kinase and mTOR-dependent manner. PMID: 14729629
    15. S6K2 is active throughout the cell cycle with higher activity in G2 and M phases. PMID: 17786541

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily
  • 數據庫鏈接：

    HGNC: 10437

    OMIM: 608939

    KEGG: hsa:6199

    STRING: 9606.ENSP00000308413

    UniGene: Hs.534345



主站蜘蛛池模板： 精品第一国产综合精品蜜芽| 国产精品v欧美精品∨日韩| 无码人妻久久一区二区三区| 久久精品人人爽人人爽| 久久午夜无码鲁丝片直播午夜精品 | 四川老熟女下面又黑又肥| 亚洲精品宾馆在线精品酒店| 在线天堂中文官网| 国产亚洲视频中文字幕97精品| 激情综合色综合久久综合| 成人片黄网站a毛片免费观看| 人妻无码中字在线a| 久久人人爽人人人人片| 中国熟妇牲交视频| 亚洲制服丝中文字幕| 男女下面一进一出无遮挡 | 另类老妇奶性生bbwbbw| 久久久久国产精品人妻aⅴ四季 | 国产高清自产拍av在线| 丰满多毛的大隂户视频| 亚洲国产精品无码中文在线| 激情综合色综合啪啪五月丁香搜索| 久久偷看各类wc女厕嘘嘘| 各处沟厕大尺度偷拍女厕嘘嘘| 久久精品国产亚洲欧美成人| 久久精品免费一区二区三区| 日韩人妻无码精品久久久不卡| 国产精品成人a区在线观看| 国产综合视频一区二区三区| 免费人成小说在线观看网站| 亚洲精品成人无码中文毛片不卡| 极品美女在线观看免费直播| 中文字幕人妻丝袜成熟乱| 任我爽精品视频在线播放| 亚洲v国产v欧美v久久久久久| 亚洲欧洲日产国产 最新| 免费观看的av毛片的网站| 黄网站欧美内射| 国产在线观看免费视频软件| 麻豆国产成人av高清在线| 在线播放五十路熟妇|