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RNF181 Antibody, HRP conjugated

  • 中文名稱:
    RNF181兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA019860LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) RNF181 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RNF181
  • 別名:
    RNF181 antibody; HSPC238 antibody; E3 ubiquitin-protein ligase RNF181 antibody; EC 2.3.2.27 antibody; RING finger protein 181 antibody; RING-type E3 ubiquitin transferase RNF181 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human E3 ubiquitin-protein ligase RNF181 protein (2-153AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
  • 基因功能參考文獻:
    1. The identification and validation of proteins interacting with HSP238 may lead to the discovery of novel mechanisms through which HSPC238 suppresses tumorigenesis in human hepatocellular carcinoma PMID: 26398855
    2. RNF181 limits the proliferation of human diffuse large B cell lymphoma cells that depend upon aberrant CARD11 signaling to NF-kappaB for growth and survival in culture. PMID: 26711259
    3. RN181 suppresses the tumorigenesis of hepatocellular carcinoma through the inhibition of ERK/MAPK signaling in the liver. PMID: 21391225
    4. Data show LOC51255 (RNF181) protein located in the cytoplasm of HePG2 cell line. PMID: 19426595
    5. The presence of RN181 in human platelets was established; RN181 has ubiquitin E3 ligase activity. PMID: 18331836

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  • 蛋白家族:
    RNF181 family
  • 組織特異性:
    Widely expressed, with highest levels in liver and heart and lowest levels in brain and skeletal muscle. Expressed in platelets (at protein level).
  • 數據庫鏈接:

    HGNC: 28037

    OMIM: 612490

    KEGG: hsa:51255

    STRING: 9606.ENSP00000306906

    UniGene: Hs.356187



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