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  4. RNF181 Antibody, Biotin conjugated

RNF181 Antibody, Biotin conjugated

  • 中文名稱：
    RNF181兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA019860LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) RNF181 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RNF181
  • 別名：
    RNF181 antibody; HSPC238 antibody; E3 ubiquitin-protein ligase RNF181 antibody; EC 2.3.2.27 antibody; RING finger protein 181 antibody; RING-type E3 ubiquitin transferase RNF181 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human E3 ubiquitin-protein ligase RNF181 protein (2-153AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
  • 基因功能參考文獻(xiàn)：
    1. The identification and validation of proteins interacting with HSP238 may lead to the discovery of novel mechanisms through which HSPC238 suppresses tumorigenesis in human hepatocellular carcinoma PMID: 26398855
    2. RNF181 limits the proliferation of human diffuse large B cell lymphoma cells that depend upon aberrant CARD11 signaling to NF-kappaB for growth and survival in culture. PMID: 26711259
    3. RN181 suppresses the tumorigenesis of hepatocellular carcinoma through the inhibition of ERK/MAPK signaling in the liver. PMID: 21391225
    4. Data show LOC51255 (RNF181) protein located in the cytoplasm of HePG2 cell line. PMID: 19426595
    5. The presence of RN181 in human platelets was established; RN181 has ubiquitin E3 ligase activity. PMID: 18331836

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  • 蛋白家族：
    RNF181 family
  • 組織特異性：
    Widely expressed, with highest levels in liver and heart and lowest levels in brain and skeletal muscle. Expressed in platelets (at protein level).
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 28037

    OMIM: 612490

    KEGG: hsa:51255

    STRING: 9606.ENSP00000306906

    UniGene: Hs.356187



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