在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

RND1 Antibody, HRP conjugated

  • 中文名稱:
    RND1兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA835694LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) RND1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RND1
  • 別名:
    ARHS antibody; FLJ42294 antibody; GTP binding protein RHO6 antibody; Ras homolog gene family member S antibody; RHO 6 antibody; Rho family GTPase 1 antibody; Rho related GTP binding protein Rho6 antibody; RHO S antibody; Rho-related GTP-binding protein Rho6 antibody; RHO6 antibody; RHOS antibody; RND 1 antibody; Rnd1 antibody; RND1_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Rho-related GTP-binding protein Rho6 protein (1-106AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments.
  • 基因功能參考文獻:
    1. Reduced RND1 expression in HCC was associated with cancer progression, likely through regulation of the Ras signaling pathway. PMID: 27770342
    2. Studies suggest that Rho GTPase signalling is a complicated mechanism in RhoA-driven cancer cell invasive migration. PMID: 27913679
    3. RND1 plays an important role in the progression of esophageal squamous cell carcinoma PMID: 26250459
    4. These results reveal a previously unappreciated mechanism through which Rnd1 restrains activation of Ras-MAPK signalling and breast tumour initiation and progression PMID: 25531777
    5. Data indicate that Rnd1 efficiently displaces Rac1 from its complex with Plexin-B1 but not vice versa. PMID: 23603360
    6. role of the N-terminal region in signaling; Rnd1 and Rnd3 have a KERRA (Lys-Glu-Arg-Arg-Ala) sequence of amino acids in their N-terminus, which functions as the lipid raft-targeting determinant; the sequence mediates lipid raft targeting of p190 RhoGAP correlated with its activation PMID: 22357615
    7. Rnd1 does not play a role in the activation of plexin-C1 and -D1 PMID: 21610070
    8. Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers PMID: 11940653
    9. The RND1 mRNA expression levels increased significantly after gestation in myometria. PMID: 16311049
    10. Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase interaction motif destabilizes dimerization of the plexin-B1 effector domain PMID: 17916560

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton.
  • 蛋白家族:
    Small GTPase superfamily, Rho family
  • 組織特異性:
    Mostly expressed in brain and liver.
  • 數據庫鏈接:

    HGNC: 18314

    OMIM: 609038

    KEGG: hsa:27289

    STRING: 9606.ENSP00000308461

    UniGene: Hs.124940



主站蜘蛛池模板: 久久久久国产精品无码免费看 | 无码人妻丰满熟妇区免费| 国产精品久久无码不卡黑寡妇| 亚洲日本va中文字幕人妖| 特黄熟妇丰满人妻无码| www国产成人免费观看视频| 永久黄网站免费视频性色| 国产精品福利2020久久| 99无码熟妇丰满人妻啪啪| 亚洲日本一区二区一本一道| 亚洲国产精品无码中文字满| 天天天天噜在线视频| 国产精品亚洲色婷婷99久久精品 | 亚洲一区二区女搞男| 国产亚洲日韩在线aaaa| 色欲综合久久躁天天躁| 欧美激情综合五月色丁香| 呦男呦女视频精品八区| aaa午夜级特黄日本大片| 亚洲伊人成综合网| 久久久久无码精品亚洲日韩| 国产成人精品免费视频大全五级| 国产精品日本亚洲777| 国产av一区二区三区最新精品 | 欧美黑人又粗又大又爽免费| 亚洲欧洲美洲无码精品va| 久久视频在线视频精品| 在线观看国产精品普通话对白精品| 东北少妇不带套对白| 国产精品亚洲精品日韩已满十八小| 成年女人免费v片| 国产精成a品人v在线播放| 国产色a在线观看| 久碰久摸久看视频在线观看| 久久久欧美精品激情| 蜜臀av 国内精品久久久| 国产在线精品一区二区三区不卡| 国内精品久久久久影院薰衣草| 色偷偷www.8888在线观看 | 国产精品无码专区在线观看 | 国产成人a人亚洲精品无码|