在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

RND1 Antibody, FITC conjugated

  • 中文名稱:
    RND1兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA835694LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) RND1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RND1
  • 別名:
    ARHS antibody; FLJ42294 antibody; GTP binding protein RHO6 antibody; Ras homolog gene family member S antibody; RHO 6 antibody; Rho family GTPase 1 antibody; Rho related GTP binding protein Rho6 antibody; RHO S antibody; Rho-related GTP-binding protein Rho6 antibody; RHO6 antibody; RHOS antibody; RND 1 antibody; Rnd1 antibody; RND1_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Rho-related GTP-binding protein Rho6 protein (1-106AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments.
  • 基因功能參考文獻:
    1. Reduced RND1 expression in HCC was associated with cancer progression, likely through regulation of the Ras signaling pathway. PMID: 27770342
    2. Studies suggest that Rho GTPase signalling is a complicated mechanism in RhoA-driven cancer cell invasive migration. PMID: 27913679
    3. RND1 plays an important role in the progression of esophageal squamous cell carcinoma PMID: 26250459
    4. These results reveal a previously unappreciated mechanism through which Rnd1 restrains activation of Ras-MAPK signalling and breast tumour initiation and progression PMID: 25531777
    5. Data indicate that Rnd1 efficiently displaces Rac1 from its complex with Plexin-B1 but not vice versa. PMID: 23603360
    6. role of the N-terminal region in signaling; Rnd1 and Rnd3 have a KERRA (Lys-Glu-Arg-Arg-Ala) sequence of amino acids in their N-terminus, which functions as the lipid raft-targeting determinant; the sequence mediates lipid raft targeting of p190 RhoGAP correlated with its activation PMID: 22357615
    7. Rnd1 does not play a role in the activation of plexin-C1 and -D1 PMID: 21610070
    8. Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers PMID: 11940653
    9. The RND1 mRNA expression levels increased significantly after gestation in myometria. PMID: 16311049
    10. Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase interaction motif destabilizes dimerization of the plexin-B1 effector domain PMID: 17916560

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton.
  • 蛋白家族:
    Small GTPase superfamily, Rho family
  • 組織特異性:
    Mostly expressed in brain and liver.
  • 數據庫鏈接:

    HGNC: 18314

    OMIM: 609038

    KEGG: hsa:27289

    STRING: 9606.ENSP00000308461

    UniGene: Hs.124940



主站蜘蛛池模板: 亚洲爆乳无码专区| 狼人无码精华av午夜精品| 国产成人无码aⅴ片在线观看| 欧美激情一区二区三区高清视频| 女同性av片在线观看免费网站| 亚洲国产成人综合一区二区三区| 亚洲欧美日韩国产综合点击进入| 人人妻碰人人免费| 国产午夜福利伦理300| 天天综合网天天综合色| 欧美xxxx做受欧美| 无码国产精品一区二区免费vr| 中文字幕人妻av一区二区| 99久久久国产精品消防器材| 无码国产精品一区二区免费16| 综合 欧美 亚洲日本| 狠狠人妻久久久久久综合| 中文字日产乱码免费1~3软件| 日韩高清在线观看永久| 久久精品女人天堂av免费观看| 亚洲成色www久久网站| 国产精品卡一卡二卡三| 玩弄少妇的肉体k8经典| 激烈的性高湖波多野结衣| 综合亚洲伊人午夜网| 欧美成人精品第一区二区三区| 国产成人精品午夜福利在线播放| 国产精品亚洲专区无码老司国 | 性欧美vr高清极品| 精品人妻少妇一区二区三区在线| 亚洲熟女久久色| 国产成av人片久青草影院| 后入内射无码人妻一区| 无码一区二区波多野结衣播放搜索 | 国产av国片精品jk制服丝袜| 毛片无码一区二区三区a片视频| 99re6热在线精品视频观看| 色欲天天天综合网| 十八禁无码免费网站| 成年女人永久免费观看视频| 国产亚洲精品久久久久久久软件|