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RMND1 Antibody, HRP conjugated

  • 中文名稱:
    RMND1兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA882123LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) RMND1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RMND1
  • 別名:
    bA351K16 antibody; bA351K16.3 antibody; C6orf96 antibody; chromosome 6 open reading frame 96 antibody; FLJ20627 antibody; MGC117362 antibody; MGC149570 antibody; MGC882602 antibody; required for meiotic nuclear division 1 homolog (S. cerevisiae) antibody; Required for meiotic nuclear division protein 1 homolog antibody; Rmnd1 antibody; RMND1_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Required for meiotic nuclear division protein 1 homolog protein (35-160AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Required for mitochondrial translation, possibly by coordinating the assembly or maintenance of the mitochondrial ribosome.
  • 基因功能參考文獻:
    1. Hearing impairment and renal failure are associated with RMND1 mutations. PMID: 26395190
    2. Expression of ESR1, RMND1 and CCDC170 associated with variants in separate enhancer elements predisposing breast cancer. [meta-analysis] PMID: 26928228
    3. Results demonstrate that the RMND1 complex is necessary for mitochondrial translation, possibly by coordinating the assembly or maintenance of the mitochondrial ribosome. PMID: 23022098
    4. The RMND1 mutation caused haploinsufficiency that was rescued by overexpression of the wild-type transcript in mutant fibroblasts; this overexpression increased the levels and activities of mitochondrial respiratory-chain proteins. PMID: 23022099
  • 相關疾病:
    Combined oxidative phosphorylation deficiency 11 (COXPD11)
  • 亞細胞定位:
    Mitochondrion.
  • 蛋白家族:
    RMD1/sif2 family
  • 數據庫鏈接:

    HGNC: 21176

    OMIM: 614917

    KEGG: hsa:55005

    STRING: 9606.ENSP00000356272

    UniGene: Hs.486835



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