在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RIOK2 Antibody, HRP conjugated

RIOK2 Antibody, HRP conjugated

  • 中文名稱：
    RIOK2兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA887136LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RIOK2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RIOK2
  • 別名：
    FLJ11159 antibody; OTTHUMP00000158911 antibody; OTTHUMP00000222868 antibody; RIO kinase 2 (yeast) antibody; RIO kinase 2 antibody; RIO2 antibody; RIOK2 antibody; RIOK2_HUMAN antibody; Serine/threonine protein kinase RIO2 antibody; Serine/threonine-protein kinase rio2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Serine/threonine-protein kinase RIO2 protein (316-448AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Serine/threonine-protein kinase involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its kinase activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre-rRNA to the mature 18S rRNA. Regulates the timing of the metaphase-anaphase transition during mitotic progression, and its phosphorylation, most likely by PLK1, regulates this function.
  • 基因功能參考文獻：
    1. These results suggested that RIOK2 and NOB1 may be potential targets in the treatment of Non-small cell lung cancer (NSCLC), and miR145 may be considered a therapeutic inhibitor of both genes. PMID: 29749434
    2. RIOK2 and NOB1 were highly expressed in NSCLC cells and tissues, and their expression profiles were significantly associated with the Tumour Node Metastasis (TNM) clinical stage, lymph node metastasis, and differentiation. RIOK2 expression was correlated with NOB1. PMID: 27346559
    3. As RIO2 is involved in the biosynthesis of the ribosome and cell cycle regulation, our selective ligand may be useful for the delineation of the biological role of this kinase. PMID: 25891899
    4. reduced expression of RIOK1 or RIOK2 disrupted Akt signaling and caused cell cycle exit, apoptosis, and chemosensitivity in glioblastoma cells PMID: 23459592
    5. Plk1-mediated phosphorylation of Rio2 regulates metaphase-anaphase transition during mitotic progression. PMID: 21880710
    6. Results show that the protein kinase human Rio2 (hRio2) is part of a late 40S preribosomal particle in human cells. PMID: 19564402

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    Protein kinase superfamily, RIO-type Ser/Thr kinase family
  • 數據庫鏈接：

    HGNC: 18999

    OMIM: 617754

    KEGG: hsa:55781

    STRING: 9606.ENSP00000283109

    UniGene: Hs.27021



主站蜘蛛池模板： 久久精品国产亚洲精品| 99久久国产露脸精品竹菊传媒| 日韩亚洲国产激情一区浪潮av| 亚洲精品无amm毛片| 蜜桃无码一区二区三区| 老司机久久精品最新免费| 狠狠色噜噜狠狠狠狠蜜桃| 大香伊人久久精品一区二区| 最近更新中文字幕| 麻豆文化传媒精品一区观看| 在线看片免费人成视频在线影院| 国产成人av大片在线播放| 最近免费中文字幕mv在线视频3| 亚洲日韩激情无码一区| 亚洲综合区小说区激情区| 偷妻之寂寞难耐2中文字幕| 国产成人精品123区免费视频| 日本乱偷互换人妻中文字幕| 人妻影音先锋啪啪av资源| 午夜dj在线观看高清在线视频完整版| 亚洲 另类 熟女 字幕| 亚洲精品专区在线观看| 熟女chachacha性少妇| 国产欧美日韩va另类在线播放| 亚洲国产aⅴ成人精品无吗| 久久久久久妓女精品影院| 国精产品蘑菇一区一区有限| 亚洲综合另类小说色区一| 精品国产乱码久久久久软件| 动漫成人无码精品一区二区三区 | 久久香蕉超碰97国产精品| 日本少妇无码精品12p| 亚洲va韩国va欧美va| 国产精品久久久久久爽爽爽 | 国产suv精二区| 女女女女女裸体处开bbb| 久久亚洲国产精品成人av秋霞 | 国产sm鞭打折磨调教视频| 丰满人妻被黑人连续中出| 狠狠躁夜夜躁人人爽天天不卡| 欧美成人h亚洲综合在线观看|