在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RIC8A Antibody

RIC8A Antibody

  • 中文名稱：
    RIC8A兔多克隆抗體
  • 貨號：
    CSB-PA878847ESR1HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA878847ESR1HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RIC8A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RIC8A
  • 別名：
    MGC104517 antibody; MGC131931 antibody; MGC148073 antibody; MGC148074 antibody; Protein Ric-8A antibody; resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) antibody; RIC8 antibody; RIC8A antibody; RIC8A_HUMAN antibody; Synembryn-A antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Synembryn-A protein (362-531AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.
  • 基因功能參考文獻：
    1. Human NCS-1 and Ric8a reproduce the binding and maintain the structural requirements at these key positions. Drosophila Ric8a and Galphas regulate synapse number and neurotransmitter release, and both are functionally linked to Frq2. PMID: 25074811
    2. Results confirmed that Ric-8A can directly bind to AGS3S but failed to facilitate Galpha(i)-induced suppression of adenylyl cyclase, suggesting that it may not serve as a guanine exchange factor for AGS3/Galpha(i/o)-GDP complex in a cellular environment. PMID: 25480567
    3. Ric-8A co-localized with Vps34 at the midbody. PMID: 24466196
    4. The ubiquitination of Galphai2 and Galphaq is suppressed by expression of Ric-8A. The suppression likely requires Ric-8A interaction with these Galpha proteins; the C-terminal truncation of Galphaq and Galphai2 completely abrogates their interaction with Ric-8A. PMID: 23665327
    5. NCAM180 regulates Ric8A membrane localization and potentiates beta-adrenergic response PMID: 22384181
    6. RGS14 can form complexes with GPCRs in cells that are dependent on Galpha(i/o) and these RGS14.Galpha(i1).GPCR complexes may be substrates for other signaling partners such as Ric-8A PMID: 21880739
    7. Ric-8A is critical for growth factor receptor-induced actin cytoskeletal reorganization PMID: 21771786
    8. Ric-8A signaling leads to assembly of a cortical signaling complex that functions to orient the mitotic spindle. PMID: 20479129

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cell membrane.
  • 蛋白家族：
    Synembryn family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 29550

    OMIM: 609146

    KEGG: hsa:60626

    STRING: 9606.ENSP00000325941

    UniGene: Hs.592292



主站蜘蛛池模板： 人妻无码久久一区二区三区免费| 亚洲欧美成人综合图区| 亚洲国产欧美在线看片一国产| 野外做受又硬又粗又大视幕| 国产在线国偷精品产拍| 国产思思99re99在线观看| 亚洲精品1卡2卡三卡4卡乱码| 久久亚洲精品无码av宋| 国产乱人伦真实精品视频| 色爱无码av综合区| 男人的好看免费观看在线视频| 国产成 人 综合 亚洲网站| 又黄又爽的60分钟视频| 欧美成年视频在线观看| 东京热人妻无码一区二区av| 2018高清日本一道国产-在| 粗大的内捧猛烈进出视频| 亚洲字幕av一区二区三区四区| 久久综合一色综合久久小蛇| 国产亚洲va在线电影| 亚洲国产精久久久久久久| 亚洲精品成人片在线播放| 国产成人无码va在线观看| 国产精品日本亚洲777| 亚洲熟妇中文字幕五十中出 | 欧美乱码卡一卡二卡四卡免费| 亚洲精品nv久久久久久久久久| 国产亲子乱弄免费视频| 国产7色在线 | 国产| 久热在线播放中文字幕| 中国内地毛片免费高清| 中文字幕日韩人妻在线视频 | 亚洲午夜无码久久久久软件| 人人澡人人澡人人看添av| 亚洲成av人片一区二区三区 | 精品国产免费一区二区三区香蕉 | 一区二区三区无码高清视频| 久久777国产线看观看精品| 两个美女裸体舌吻互扒内裤| 欧美成人aa大片| 中国极品少妇xxxxx|