在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

RHCG Antibody, FITC conjugated

  • 中文名稱:
    RHCG兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA880059LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) RHCG Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RHCG
  • 別名:
    Ammonium transporter Rh type C antibody; C15orf6 antibody; CDRC2 antibody; chromosome 15 open reading frame 6 antibody; PDRC2 antibody; Rh family type C glycoprotein antibody; Rh glycoprotein kidney antibody; Rh type C glycoprotein antibody; rhcg antibody; RHCG_HUMAN antibody; Rhesus blood group family type C glycoprotein antibody; Rhesus blood group; C glycoprotein antibody; RHGK antibody; SLC42A3 antibody; Tumor-related protein DRC2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Ammonium transporter Rh type C protein (416-479AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion.
  • 基因功能參考文獻:
    1. RhCG and H+ATPases are located within the same cellular protein complex in the kidney and this interaction is required for maximal urinary acidification by H+-ATPases, a prerequisite for efficient NH3 secretion and urine excretion of NH4+. PMID: 29054531
    2. RHCG was down-regulated in cervical cancers compared to that in normal cervical tissues, and further decreased in cervical cancer cell lines. Functionally, RHCG overexpression reduced cervical cancer cell proliferation and migration, as evidenced by the decreased transforming growth factor (TGF)-beta1, matrix metalloproteinase (MMP)-2 and MMP-9 expressions in cancer cells. PMID: 29852177
    3. The results support the notion that RHCG is a novel tumor suppressor gene that plays an important role in the development and progression of ESCC. PMID: 29290801
    4. The molecular mechanism of NH4(+) recruitment and NH3 transport by RHCG is described. PMID: 26190573
    5. Rh B Glycoprotein (Rhbg) and Rh C Glycoprotein (Rhcg) are identified as ammonia transporters. They are expressed in specific cell populations and membrane domains in distal renal epithelial cells, where they facilitate ammonia secretion. PMID: 24647713
    6. RhAG, RhBG and RhCG-exhibit significant permeability to NH3 and show for the first time that RhBG and RhCG can conduct CO2. PMID: 24077989
    7. Amt and Rh proteins are not functionally equivalent and that permeation takes place according to two distinct mechanisms. PMID: 24021113
    8. X-ray crystallographic structure of human RhCG, determined at 2.1 A resolution, reveals the mechanism of ammonia transport. PMID: 20457942
    9. major finding of this study is that RhCG protein is active as an NH(3) channel and that this function does not require any protein partner PMID: 20126667
    10. RhBG and RhCG facilitate ammonium movement across the plasma membrane; these results favor the hypothesis that these Rh glycoproteins, together with their homolog RhAG, constitute a family of NH3 channels in mammalian cells. PMID: 15929723
    11. RhCG expression enhanced the ammonium-induced initial alkalinization (related to NH3 influx)& secondary acidification (related to NH4+ influx). Sub-millimolar NH4+ concentrations induced inward currents in voltage-clamped RhCG-expressing cells. PMID: 16564724
    12. Review. Mutations at positions F74, V137 and F235 resulted in a severe reduction of NH3 transport. PMID: 16580862
    13. This study concludes that under normal conditions, RhCG is the major putative ammonia transporter expressed in the human kidney and RhBG is not expressed at detectable levels. PMID: 19357182
    14. Rhbg and Rhcg may contribute to bronchial epithelial cell ammonia metabolism and suggest that they do not contribute to pulmonary carbon dioxide transport. PMID: 19429772

    顯示更多

    收起更多

  • 亞細胞定位:
    Apical cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Ammonium transporter (TC 2.A.49) family, Rh subfamily
  • 組織特異性:
    Expressed in brain, testis, placenta, pancreas, esophagus and prostate. Expressed in squamous epithelial tissues (at protein level). According to PubMed:11062476, specifically expressed in kidney.
  • 數據庫鏈接:

    HGNC: 18140

    OMIM: 605381

    KEGG: hsa:51458

    STRING: 9606.ENSP00000268122

    UniGene: Hs.459284



主站蜘蛛池模板: 成 人 网 站94免费观看| 亚洲熟妇无码一区二区三区导航| 日韩av无码国产精品| 国内精品久久久久久影院| 国内精品久久久久影院老司机| 99热网址最新获取域名| 三级国产三级在线| 亚洲欧美乱日韩乱国产| 久久久久人妻一区精品色欧美 | 丰满人妻在公车被猛烈进入电影| 色av综合av综合无码网站| 99久久无色码中文字幕| 国产最新精品自产在线观看| 国产公开免费人成视频| 国产免费久久精品99久久| 欧美zozo另类特级| a∨在线视频播放| 手机在线看永久av片免费| 阳茎伸入女人阳道视频免费| 国产精品亚洲а∨天堂网| 狂野欧美激情性xxxx在线观看| 色老头在线一区二区三区| 久久精品这里热有精品| 国产欧美日韩视频怡春院| 2022一本久道久久综合狂躁| 久久久精品国产免大香伊| 亚洲日韩成人性av网站| 国产一区二区亚洲精品| 北条麻妃在线一区二区| 中文在线а√在线| 丝袜老师高潮呻吟高潮| 人人爽人人爽人人爽| 无码熟妇人妻av在线影片| 国内揄拍国内精品人妻| 未满十八18禁止午夜免费网站| 天天狠天天透天干天天怕∴| 天干天干天啪啪夜爽爽99| 午夜无码片在线观看影院y| 国内揄拍国内精品少妇| 狠狠色综合7777久夜色撩人ⅰ| 特殊重囗味sm在线观看无码|