在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RHBDF2 Antibody, FITC conjugated

RHBDF2 Antibody, FITC conjugated

  • 中文名稱：
    RHBDF2兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA744137LC11HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) RHBDF2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Inactive rhomboid protein 2 (iRhom2) (Rhomboid 5 homolog 2) (Rhomboid family member 2) (Rhomboid veinlet-like protein 5) (Rhomboid veinlet-like protein 6), RHBDF2, IRHOM2 RHBDL5 RHBDL6
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Inactive rhomboid protein 2 protein (1-200aa)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.
  • 基因功能參考文獻：
    1. Study identified iRHOM2 as a novel regulator of K16 in humans and mice, with important implications for palmoplantar keratodermas, wound healing, inflammatory skin disease and cancers. PMID: 28128203
    2. Uev1A-Ubc13 complex catalyzes lysine63-linked ubiquitination of RHBDF2 to promote TACE maturation. PMID: 29069608
    3. The iRhom2 N-terminus stabilizes mature ADAM17 at the cell surface where it cleaves TNF and EGFR in inflammatory and innate immune responses. (Review) PMID: 28815577
    4. Tylosis with oesophageal cancer-associated mutations in iRHOM2 cause an increase in the maturation and activity of ADAM17 in epidermal keratinocytes. PMID: 24643277
    5. Our analyses suggest that these DNA methylation changes may have a role in the onset of Alzheimer disease given that we observed them in presymptomatic subjects and that six of the validated genes connect to a known susceptibility gene network. PMID: 25129075
    6. Identification of a new missense mutation, p.Asp188Asn, segregating with tylosis with esophageal cancer in a Finnish family, and interestingly the detected mutation alters a codon located between the two previously reported mutation sites. PMID: 22638770
    7. RHBDF2 and CYGB may play distinctive roles in ovarian cancer and could be added to the growing roster of chromosome 17 genes implicated in this disease. PMID: 22344671
    8. The distribution of RHBDF2 in tylotic skin is altered in comparison with that in normal skin. PMID: 22265016

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Tylosis with esophageal cancer (TOC)
  • 亞細胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane.
  • 蛋白家族：
    Peptidase S54 family
  • 組織特異性：
    Found in the epidermis and esophageal epithelium.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 20788

    OMIM: 148500

    KEGG: hsa:79651

    STRING: 9606.ENSP00000322775

    UniGene: Hs.464157



主站蜘蛛池模板： av无码av无码专区| 日本最新免费二区| 国产国拍精品av在线观看| 97人洗澡人人澡人人爽人人模| 国产成人mv视频在线观看| 亚洲最大无码av网站观看| 国产午夜无码福利在线看网站| 久久午夜神器| 女人被狂躁c到高潮视频| 欧美506070老妇乱子伦| 国产成人午夜在线视频a站| 国产午夜福利精品久久2021| 国产精品igao视频| 日韩乱码人妻无码中文字幕视频| 国产成人亚洲精品另类动态| 欧美性色老妇人| 国产情侣一区二区| 老妇女性较大毛片| 久久久亚洲欧洲日产国码606| 日韩亚洲中字无码一区二区三区| 夜夜天天噜狠狠爱2019| 国产美女自慰在线观看| 无遮无挡三级动态图| 中日韩精品卡一卡二卡3卡| 99久久精品国产波多野结衣| 国内揄拍高清国内精品对白 | 国产真实乱对白精彩| 中文字幕无码日韩欧免费软件 | 亚洲欧美日韩久久精品第一区 | 日韩精品无码成人专区| 尹人香蕉99久久综合网站| 色 综合 欧美 亚洲 国产| 97人妻人人揉人人躁人人| 2020最新国产在线不卡a| 成人av一本不卡二卡| 亚洲中文字幕无码爆乳av| h无码动漫在线观看| 成年黄页网站大全免费无码| 精品国产污污免费网站入口| 欧美国产日韩a在线视频| 国产在线第一区二区三区|