在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RHBDF2 Antibody, Biotin conjugated

RHBDF2 Antibody, Biotin conjugated

  • 中文名稱：
    RHBDF2兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA744137LD21HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) RHBDF2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Inactive rhomboid protein 2 (iRhom2) (Rhomboid 5 homolog 2) (Rhomboid family member 2) (Rhomboid veinlet-like protein 5) (Rhomboid veinlet-like protein 6), RHBDF2, IRHOM2 RHBDL5 RHBDL6
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Inactive rhomboid protein 2 protein (1-200aa)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.
  • 基因功能參考文獻(xiàn)：
    1. Study identified iRHOM2 as a novel regulator of K16 in humans and mice, with important implications for palmoplantar keratodermas, wound healing, inflammatory skin disease and cancers. PMID: 28128203
    2. Uev1A-Ubc13 complex catalyzes lysine63-linked ubiquitination of RHBDF2 to promote TACE maturation. PMID: 29069608
    3. The iRhom2 N-terminus stabilizes mature ADAM17 at the cell surface where it cleaves TNF and EGFR in inflammatory and innate immune responses. (Review) PMID: 28815577
    4. Tylosis with oesophageal cancer-associated mutations in iRHOM2 cause an increase in the maturation and activity of ADAM17 in epidermal keratinocytes. PMID: 24643277
    5. Our analyses suggest that these DNA methylation changes may have a role in the onset of Alzheimer disease given that we observed them in presymptomatic subjects and that six of the validated genes connect to a known susceptibility gene network. PMID: 25129075
    6. Identification of a new missense mutation, p.Asp188Asn, segregating with tylosis with esophageal cancer in a Finnish family, and interestingly the detected mutation alters a codon located between the two previously reported mutation sites. PMID: 22638770
    7. RHBDF2 and CYGB may play distinctive roles in ovarian cancer and could be added to the growing roster of chromosome 17 genes implicated in this disease. PMID: 22344671
    8. The distribution of RHBDF2 in tylotic skin is altered in comparison with that in normal skin. PMID: 22265016

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Tylosis with esophageal cancer (TOC)
  • 亞細(xì)胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane.
  • 蛋白家族：
    Peptidase S54 family
  • 組織特異性：
    Found in the epidermis and esophageal epithelium.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 20788

    OMIM: 148500

    KEGG: hsa:79651

    STRING: 9606.ENSP00000322775

    UniGene: Hs.464157



主站蜘蛛池模板： 私人家庭影院5777| 99久久精品免费看国产一区二区| 中文日产乱幕九区无线码| 亚洲人成电影在线天堂色| 亚洲一区二区三区播放| 国产乱子伦一区二区三区| 国产亚洲综合网曝门系列| 国产乱子伦精品免费视频| 无码视频在线观看| 国产女主播白浆在线观看| 92国产精品午夜免费福利视频| 国产精品久久久久电影网| 日本精品人妻无码免费大全| 亚洲va欧美va天堂v国产综合| 国产在线无码制服丝袜无码 | 国产精品国产亚洲精品看不卡| 成人免费777777| 国产成+人+综合+亚洲专区| 国产人妻人伦精品久久久| av老司机亚洲精品天堂| 性xxxxx大片免费视频| 四十如虎的丰满熟妇啪啪| 精品无码国产自产拍在线观看| 人人妻在人人| 日本又黄又潮娇喘视频| 国产成人av在线影院无毒 | 猫咪www免费人成人入口| 国产日产欧产精品精品| 天堂岛国av无码免费无禁网站| 天天躁日日躁aaaaxxxx| 成人内射国产免费观看| 欧美黑人巨大videos精品男男| 日本丰满人妻xxxxxhd| 99亚洲男女激情在线观看| 人妻少妇久久中文字幕456| 少妇熟女久久综合网色欲| 美女内射毛片在线看3d| 精品久久久久久久久久久国产字幕| 伊人伊成久久人综合网996| 无码视频在线观看| 国产精品久久久亚洲|