在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RGS3 Antibody

RGS3 Antibody

  • 中文名稱：
    RGS3兔多克隆抗體
  • 貨號(hào)：
    CSB-PA019655ESR1HU
  • 規(guī)格：
    ￥440
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) RGS3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RGS3
  • 別名：
    C2PA antibody; FLJ20370 antibody; FLJ31516 antibody; FLJ90496 antibody; PDZ RGS 3 antibody; PDZ RGS3 antibody; Regulator of G protein signaling 3 antibody; Regulator of G protein signalling 3 antibody; Regulator of G-protein signaling 3 antibody; RGP 3 antibody; RGP3 antibody; RGS 3 antibody; RGS3 antibody; RGS3_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Regulator of G-protein signaling 3 protein (1-270AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases.
  • 基因功能參考文獻(xiàn)：
    1. It has been reported that mitotic kinesin KIF20A interacts with RGS3 and plays a crucial role in controlling the division modes of neural progenitor cells during cortical neurogenesis. PMID: 30006548
    2. Findings suggest that overexpressed RGS3 regulated by microRNA-126 through the post-transcriptional modulation is associated significantly with a poor prognosis of GC patients. PMID: 27754994
    3. Our data provide a novel miR-25/RGS3 signal in the development of lung cancer. PMID: 26416661
    4. cardiac overexpression of RGS3 inhibits maladaptive hypertrophy and fibrosis and improves cardiac function by blocking MEK-ERK1/2 signaling PMID: 24375609
    5. PDZ-RGS3 can enhance signals generated by the Wnt canonical pathway and plays a pivotal role in epithelial mesenchymal transition PMID: 22859293
    6. Results suggest that the 14-3-3 protein binding affects the structure of the Galpha interaction portion of RGS3 as well as sterically blocks the interaction between the RGS domain and the Galpha subunit of heterotrimeric G proteins. PMID: 22027839
    7. 14-3-3 protein binding induces structural changes in both the N-terminal part and the C-terminal RGS domain of phosphorylated RGS3 molecule PMID: 20347994
    8. Regulator of G-protein signalling 3 (RGS3) showed a difference between follicular cells from follicles leading to a pregnancy or developmental failure. PMID: 19778949
    9. Data are consistent with the model wherein 14-3-3 serves as a scavenger of RGS3, regulating the amounts of RGS3 available for binding G-proteins. PMID: 11985497
    10. C2PA is expressed in the cell nucleus and induces heat shock response element (HSE)-dependent gene transcription PMID: 12210723
    11. RFS3 promoted the conversion of more stable Ca2+ elevations into oscillatory signals. PMID: 15383626
    12. mRNA expression of CCT5, RGS3, and YKT6 was significantly up-regulated in p53-mutated tumors and associated with a low response rate to docetaxel. PMID: 16821082
    13. Full-length RGS3, RGS3T, and the core domain of RGS3 were equally effective in antagonizing inhibition of Ca(V)2.3 through M(2)R. PMID: 16855219
    14. This study identifies a novel, noncanonical role of RGS3 in regulation of TGF-beta signaling through its interaction with Smads and interfering with Smad heteromerization. PMID: 18287247
    15. in apoptosis-initiated cells, the ligand-dependent C5aR-mediated dual signal affects the fate of cells, either apoptosis execution or survival, through regulation of RGS3 gene expression and subsequent modulation of ERK signal. PMID: 19333232

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Note=Long isoforms are cytoplasmic and associated with the plasma membrane (PubMed:9858594). Short isoforms are nuclear (PubMed:10749886).
  • 數(shù)據(jù)庫鏈接：

    HGNC: 9999

    OMIM: 602189

    KEGG: hsa:5998

    STRING: 9606.ENSP00000259406

    UniGene: Hs.494875



主站蜘蛛池模板： 忍不住的亲子中文字幕| 成人无码a∨电影免费| 国偷自产视频一区二区久| 麻豆一区二区三区蜜桃免费| 久久久久久人妻一区精品| 狼友av永久网站免费观看孕交| 国产网曝门亚洲综合在线| 色妞www精品视频| 国产成人精品无码片区在线观看| av无码久久久久不卡蜜桃| 中文资源在线天堂库8| 欧美婷婷六月丁香综合色 | 人妻少妇88久久中文字幕| 国产精品第12页| 久久精品中文无码资源站| 人人揉揉揉香蕉大免费| 人人爽人人爽人人片av亚洲| 成人影片一区免费观看| 国产在线一卡2卡三卡4卡免费| 国产成熟妇女性视频电影| 女人夜夜春精品a片| 狠狠色综合7777久夜色撩人 | 日韩激情无码免费毛片| 国产亚洲精品无码不卡| 亚洲精品无码ma在线观看| 国产欧美久久一区二区| 中国女人大白屁股ass| 97se亚洲国产综合自在线| 人妻少妇久久久久久97人妻| 香蕉久久一区二区三区啪啪| 亚洲国产欧美不卡在线观看| 青青草原精品资源站久久| 男人一边吃奶一边做爰免费视频| 无码国产精品免费看| 欧美人与动牲交免费观看网| 无码人妻一区二区三区线| 日躁夜躁狠狠躁2001| 天堂久久天堂av色综合| 国产精品美女久久久久av爽李琼| 新狼窝色av性久久久久久| 中文字幕+乱码+中文乱码www |