在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

RGS3 Antibody

  • 中文名稱:
    RGS3兔多克隆抗體
  • 貨號(hào):
    CSB-PA019655GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    RGS3
  • 別名:
    C2PA antibody; FLJ20370 antibody; FLJ31516 antibody; FLJ90496 antibody; PDZ RGS 3 antibody; PDZ RGS3 antibody; Regulator of G protein signaling 3 antibody; Regulator of G protein signalling 3 antibody; Regulator of G-protein signaling 3 antibody; RGP 3 antibody; RGP3 antibody; RGS 3 antibody; RGS3 antibody; RGS3_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human RGS3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,IHC
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases.
  • 基因功能參考文獻(xiàn):
    1. It has been reported that mitotic kinesin KIF20A interacts with RGS3 and plays a crucial role in controlling the division modes of neural progenitor cells during cortical neurogenesis. PMID: 30006548
    2. Findings suggest that overexpressed RGS3 regulated by microRNA-126 through the post-transcriptional modulation is associated significantly with a poor prognosis of GC patients. PMID: 27754994
    3. Our data provide a novel miR-25/RGS3 signal in the development of lung cancer. PMID: 26416661
    4. cardiac overexpression of RGS3 inhibits maladaptive hypertrophy and fibrosis and improves cardiac function by blocking MEK-ERK1/2 signaling PMID: 24375609
    5. PDZ-RGS3 can enhance signals generated by the Wnt canonical pathway and plays a pivotal role in epithelial mesenchymal transition PMID: 22859293
    6. Results suggest that the 14-3-3 protein binding affects the structure of the Galpha interaction portion of RGS3 as well as sterically blocks the interaction between the RGS domain and the Galpha subunit of heterotrimeric G proteins. PMID: 22027839
    7. 14-3-3 protein binding induces structural changes in both the N-terminal part and the C-terminal RGS domain of phosphorylated RGS3 molecule PMID: 20347994
    8. Regulator of G-protein signalling 3 (RGS3) showed a difference between follicular cells from follicles leading to a pregnancy or developmental failure. PMID: 19778949
    9. Data are consistent with the model wherein 14-3-3 serves as a scavenger of RGS3, regulating the amounts of RGS3 available for binding G-proteins. PMID: 11985497
    10. C2PA is expressed in the cell nucleus and induces heat shock response element (HSE)-dependent gene transcription PMID: 12210723
    11. RFS3 promoted the conversion of more stable Ca2+ elevations into oscillatory signals. PMID: 15383626
    12. mRNA expression of CCT5, RGS3, and YKT6 was significantly up-regulated in p53-mutated tumors and associated with a low response rate to docetaxel. PMID: 16821082
    13. Full-length RGS3, RGS3T, and the core domain of RGS3 were equally effective in antagonizing inhibition of Ca(V)2.3 through M(2)R. PMID: 16855219
    14. This study identifies a novel, noncanonical role of RGS3 in regulation of TGF-beta signaling through its interaction with Smads and interfering with Smad heteromerization. PMID: 18287247
    15. in apoptosis-initiated cells, the ligand-dependent C5aR-mediated dual signal affects the fate of cells, either apoptosis execution or survival, through regulation of RGS3 gene expression and subsequent modulation of ERK signal. PMID: 19333232

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Note=Long isoforms are cytoplasmic and associated with the plasma membrane (PubMed:9858594). Short isoforms are nuclear (PubMed:10749886).
  • 數(shù)據(jù)庫鏈接:

    HGNC: 9999

    OMIM: 602189

    KEGG: hsa:5998

    STRING: 9606.ENSP00000259406

    UniGene: Hs.494875



主站蜘蛛池模板: 在线天堂资源www在线污| 无码人妻丰满熟妇啪啪| 欧美乱妇狂野欧美在线视频| 最新高清中文字幕免费mv| 国产av影片麻豆精品传媒| 国产成人无码午夜视频在线播放| 精品无码一区二区三区| av大片在线无码永久免费| 夜夜高潮夜夜爽夜夜爱爱一区| 中文区中文字幕免费看| 中国熟妇牲交视频免费| 先锋影音av资源站av| 九九久久精品国产| 人妻激情偷乱视频一区二区三区| 阳茎伸入女人阳道视频| 国产成熟妇女性视频电影| 999久久久免费精品国产| 丰满人妻熟妇乱又伦精品视| 青青国产揄拍视频| 国内精品2020情侣视频| 人人爽人人爽人人片av亚洲| 久久精品国产免费观看| 亚洲欧美日韩成人综合一区| 久久婷婷六月综合色液啪| 真实国产乱子伦对白在线播放 | 国产成人亚洲综合网站小说| 欧美亚洲高清国产| 少妇私密会所按摩到高潮呻吟| 国精品人妻无码一区二区三区d3| 被窝的午夜无码福利专区| 四虎www成人影院观看| 农民人伦一区二区三区| 青草视频在线播放| 国产精品欧美成人片| 欧美天天综合色影久久精品| 成在线人免费视频| 伦理片午夜视频在线观看| 欧洲精品卡一卡二卡三| 精品日本一区二区三区在线观看| 99热门精品一区二区三区无码| av在线播放日韩亚洲欧我不卡|