在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RGS14 Antibody

RGS14 Antibody

  • 中文名稱：
    RGS14兔多克隆抗體
  • 貨號：
    CSB-PA006675
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of 3T3 cells using RGS14 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    Highly similar to rap1/rap2 interacting protein antibody; OTTHUMP00000223586 antibody; OTTHUMP00000223587 antibody; Regulation of G protein signaling 14 antibody; Regulator of G protein signaling 14 antibody; Regulator of G protein signalling 14 antibody; Regulator of G-protein signaling 14 antibody; RGS 14 antibody; RGS14 antibody; RGS14_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human RGS14.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Besides, modulates signal transduction via G protein alpha subunits by functioning as a GDP-dissociation inhibitor (GDI). Has GDI activity on G(i) alpha subunits GNAI1 and GNAI3, but not on GNAI2 and G(o) alpha subunit GNAO1. Has GAP activity on GNAI0, GNAI2 and GNAI3. May act as a scaffold integrating G protein and Ras/Raf MAPkinase signaling pathways. Inhibits platelet-derived growth factor (PDGF)-stimulated ERK1/ERK2 phosphorylation; a process depending on its interaction with HRAS and that is reversed by G(i) alpha subunit GNAI1. Acts as a positive modulator of microtubule polymerisation and spindle organization through a G(i)-alpha-dependent mechanism. Plays a role in cell division. Required for the nerve growth factor (NGF)-mediated neurite outgrowth. Involved in stress resistance. May be involved in visual memory processing capacity and hippocampal-based learning and memory.
  • 基因功能參考文獻：
    1. Data support the notion that the Galpha, but not Gbetagamma, arm of the Gi/o signalling is involved in TRPC4 activation and unveil new roles for RGS and RGS14 in fine-tuning TRPC4 activities. PMID: 26987813
    2. The RBD region associates with the RGS domain region, producing an intramolecular interaction within RGS14 that enhances the GTPase activating function. PMID: 23255434
    3. RGS14 can form complexes with GPCRs in cells that are dependent on Galpha(i/o) and these RGS14.Galpha(i1).GPCR complexes may be substrates for other signaling partners such as Ric-8A PMID: 21880739
    4. RGS-14 may facilitate cognitive processing by modulating Cav1 channel-mediated intracellular divalent calcium ion Ca(2)+ transients. PMID: 20842066
    5. RGS14 serves as a novel scaffold to integrate GTP-Binding Protein alpha Subunit and Ras/Raf/MAPkinase signalling events through the action of its GL domain. PMID: 19878719
    6. We show that RGS14 is a component of mitotic asters formed in vitro from HeLa cell extracts and that depletion of RGS14 from cell extracts blocks aster formation. PMID: 15917656
    7. NMR 1H, 13C and 15N resonances of the RGS domain (residues 56-207) PMID: 19636837

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Nucleus, PML body. Cytoplasm. Membrane. Cell membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Cell projection, dendrite. Cell projection, dendritic spine. Cell junction, synapse, postsynaptic density.
  • 數據庫鏈接：

    HGNC: 9996

    OMIM: 602513

    KEGG: hsa:10636

    STRING: 9606.ENSP00000386229

    UniGene: Hs.9347



主站蜘蛛池模板： 免费无码午夜福利片69| www国产内插视频| 欧美丰满熟妇bbbbbb| 四房播播开心五月| 狠狠做深爱婷婷丁香综合| 天天澡日日澡狠狠欧美老妇| 亚洲色中文字幕在线播放| 国产精品亚洲综合一区二区三区| 久久一日本道色综合久久| 激情毛片无码专区| 一区二区三区鲁丝不卡麻豆| 国产无套粉嫩白浆在线观看| 久久精品人妻无码一区二区三区 | 性一交一无一伦一精一品| 动漫人妻h无码中文字幕| 少妇被粗大的猛进出69影院| 欧美 亚洲 日韩 中文2019| 国产成人拍精品视频午夜网站 | 天天干天天日夜夜操| 精品少妇ay一区二区三区| 久久香蕉国产线看观看手机| 亚洲国产成人精品无码区一本| 国产疯狂伦交大片| 久久久久人妻精品一区蜜桃 | 久久久亚洲精品成人| 免费观看又色又爽又黄的韩国| 日韩经典精品无码一区| 色哟哟最新在线观看入口| 亚洲国产欧美在线观看| 成av人片在线观看www| 精品一卡2卡三卡4卡乱码精品视频| 色88久久久久高潮综合影院| 亚洲va欧美va天堂v国产综合| 琪琪秋霞午夜av影视在线| 国产成人精品日本亚洲成熟| 亚洲中文字幕一区精品自拍| 日韩va中文字幕无码电影| 久久午夜夜伦鲁鲁片免费无码影视| 亚洲中文超碰中文字幕| 国产激情з∠视频一区二区 | 国产成人综合久久精品推下载|