在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RD3 Antibody, FITC conjugated

RD3 Antibody, FITC conjugated

  • 中文名稱：
    RD3兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA800101LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RD3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RD3
  • 別名：
    RD3 antibody; C1orf36 antibody; Protein RD3 antibody; Retinal degeneration protein 3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Protein RD3 protein (1-195AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plays a critical role in the regulation of enzymes involved in nucleotide cycle in photoreceptors. Inhibits the basal catalytic activity and the GCAP-stimulated activity of GUCY2D and GUCY2F, two retinal guanylyl cyclases involved in the production of cGMP in photoreceptors. Involved in the transport of GUCY2D and GUCY2F to their target sites in the photoreceptor outer segment. Up-regulates the activity of GUK1, a kinase that plays also an essential role for recycling GMP and indirectly, cGMP. Plays an important role for the survival of rods and cones in the retina.
  • 基因功能參考文獻：
    1. Re-expressing RD3 in metastatic site-derived aggressive cells reverted their metastatic potential both in vitro and in vivo. Conversely muting RD3 in neuroblastoma cells not only heightened invasion/migration but also dictated aggressive disease with metastasis. PMID: 26375249
    2. This study reports the results of an international study aimed at delineating the clinical and molecular spectrum of RD3 mutations in retinal dystrophies. PMID: 23308101
    3. Mutations in RD3 are a very rare cause of Leber's congenital amaurosis (LCA) associated with an extremely severe form of retinal dystrophy. PMID: 22531706
    4. RD3 suppresses the basal catalytic activity of guanylyl cyclase activating proteins (GCAP) in a noncompetitive manner. PMID: 21928830
    5. Identification and sequence analysis of C1orf36. PMID: 12914764
    6. the retinopathy-associated RD3 protein is part of subnuclear protein complexes involved in diverse processes, such as transcription and splicing. PMID: 17186464

    顯示更多

    收起更多

  • 相關疾病：
    Leber congenital amaurosis 12 (LCA12)
  • 亞細胞定位：
    Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment. Endosome. Nucleus. Cytoplasm. Cytoplasm, perinuclear region.
  • 組織特異性：
    Expressed in retina. Widely expressed (at protein level). In the retina the strongest immunoreactivity is detected in the inner half of the cytoplasmic portion of the photoreceptor layer, where rods and cones are found, and the external half of the outer
  • 數據庫鏈接：

    HGNC: 19689

    OMIM: 180040

    KEGG: hsa:343035

    STRING: 9606.ENSP00000355969

    UniGene: Hs.632495



主站蜘蛛池模板： 亚洲鲁丝片一区二区三区| 无码熟妇人妻av在线电影| 亚洲人成网站18禁止无码| 欧美黑人欧美精品刺激| 无码动漫性爽xo视频在线观看 | 国产精品熟妇一区二区三区四区 | 国产婷婷成人久久av免费高清| 亚洲中文字幕码在线电影| 人妻aⅴ中文字幕无码| 丰满肥臀大屁股熟妇激情视频| 久久久久欧美精品| 亚洲一区波多野结衣在线| 丰满熟女高潮毛茸茸欧洲视频| 两个奶头被吃高潮视频| 欧美午夜理伦三级在线观看| 久久久久久伊人高潮影院| 同性女女黄h片在线播放| 国产亚洲精品在av| 男女性爽大片视频| 亚洲视频日本有码中文| 亚洲一卡2卡三卡4卡无卡下载 | 婷婷丁香五月中文字幕| 性荡视频播放在线视频| 国产1卡2卡3卡4卡免费| 麻豆果冻传媒2021精品传媒一区| 97人妻人人揉人人躁人人| 在线岛国片免费无码av| 日本日本熟妇中文在线视频| 性欧美大战久久久久久久久| 男女啪啪做爰高潮无遮挡| 2018年秋霞无码片| 精品国产一区二区三区无码| 色综合99久久久无码国产精品| 伊人无码一区二区三区| 内射女校花一区二区三区| 日本丰满少妇裸体自慰| 播五月开心婷婷欧美综合| 黄页网站视频免费大全| 久久精品国产免费观看| 两个美女裸体舌吻互扒内裤| 国产福利永久在线视频无毒不卡|