在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

RD3 Antibody, FITC conjugated

  • 中文名稱:
    RD3兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA800101LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) RD3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RD3
  • 別名:
    RD3 antibody; C1orf36 antibody; Protein RD3 antibody; Retinal degeneration protein 3 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Protein RD3 protein (1-195AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Plays a critical role in the regulation of enzymes involved in nucleotide cycle in photoreceptors. Inhibits the basal catalytic activity and the GCAP-stimulated activity of GUCY2D and GUCY2F, two retinal guanylyl cyclases involved in the production of cGMP in photoreceptors. Involved in the transport of GUCY2D and GUCY2F to their target sites in the photoreceptor outer segment. Up-regulates the activity of GUK1, a kinase that plays also an essential role for recycling GMP and indirectly, cGMP. Plays an important role for the survival of rods and cones in the retina.
  • 基因功能參考文獻:
    1. Re-expressing RD3 in metastatic site-derived aggressive cells reverted their metastatic potential both in vitro and in vivo. Conversely muting RD3 in neuroblastoma cells not only heightened invasion/migration but also dictated aggressive disease with metastasis. PMID: 26375249
    2. This study reports the results of an international study aimed at delineating the clinical and molecular spectrum of RD3 mutations in retinal dystrophies. PMID: 23308101
    3. Mutations in RD3 are a very rare cause of Leber's congenital amaurosis (LCA) associated with an extremely severe form of retinal dystrophy. PMID: 22531706
    4. RD3 suppresses the basal catalytic activity of guanylyl cyclase activating proteins (GCAP) in a noncompetitive manner. PMID: 21928830
    5. Identification and sequence analysis of C1orf36. PMID: 12914764
    6. the retinopathy-associated RD3 protein is part of subnuclear protein complexes involved in diverse processes, such as transcription and splicing. PMID: 17186464

    顯示更多

    收起更多

  • 相關疾病:
    Leber congenital amaurosis 12 (LCA12)
  • 亞細胞定位:
    Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment. Endosome. Nucleus. Cytoplasm. Cytoplasm, perinuclear region.
  • 組織特異性:
    Expressed in retina. Widely expressed (at protein level). In the retina the strongest immunoreactivity is detected in the inner half of the cytoplasmic portion of the photoreceptor layer, where rods and cones are found, and the external half of the outer
  • 數據庫鏈接:

    HGNC: 19689

    OMIM: 180040

    KEGG: hsa:343035

    STRING: 9606.ENSP00000355969

    UniGene: Hs.632495



主站蜘蛛池模板: 中文无码精品a∨在线| 中文字幕亚洲码在线观看| aⅴ亚洲 日韩 色 图网站 播放| 99热在线精品免费全部my| 精品乱子伦一区二区三区| 一本一本久久aa综合精品| 亚洲午夜精品一区二区| 日韩国产高清一区二区| 中文在线а√在线天堂中文| 亚洲人成无码网www电影榴莲| 好紧好爽免费午夜视频| 欧美精品v欧洲精品| 人妻av无码专区| 丰满少妇被猛烈进入无码| 亚洲码国产精品高潮在线| 少妇高潮流白浆在线观看| 日本丰满熟妇乱子伦| 日产精品一卡2卡三卡4乱码| 噜噜高清欧美内射短视频| 屁屁影院ccyy备用地址| 精品国产乱码久久久久久郑州公司| 西西人体444www大胆无码视频 | 国内精品久久久久电影院| 丰满大肥婆肥奶大屁股| 免费又黄又爽又色的视频| 国产成人精品男人的天堂| 97影院理论午夜伦不卡| 欧美人与禽zozzo性伦交| 亚洲国产桃花岛一区二区| 玩弄白嫩少妇xxxxx性| 久久综合久久鬼色| 日本公与熄乱理在线播放| 国产精品a久久777777| 国产精品亚洲色婷婷99久久精品| 国产日产亚洲系列最新| 色偷偷av一区二区三区| 久久综合少妇11p| 日本一本一区二区免费播放| 东京热加勒比无码少妇| 欧美国产国产综合视频| 日韩一区二区三区北条麻妃|