在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RD3 Antibody, FITC conjugated

RD3 Antibody, FITC conjugated

  • 中文名稱：
    RD3兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA800101LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RD3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RD3
  • 別名：
    RD3 antibody; C1orf36 antibody; Protein RD3 antibody; Retinal degeneration protein 3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Protein RD3 protein (1-195AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plays a critical role in the regulation of enzymes involved in nucleotide cycle in photoreceptors. Inhibits the basal catalytic activity and the GCAP-stimulated activity of GUCY2D and GUCY2F, two retinal guanylyl cyclases involved in the production of cGMP in photoreceptors. Involved in the transport of GUCY2D and GUCY2F to their target sites in the photoreceptor outer segment. Up-regulates the activity of GUK1, a kinase that plays also an essential role for recycling GMP and indirectly, cGMP. Plays an important role for the survival of rods and cones in the retina.
  • 基因功能參考文獻：
    1. Re-expressing RD3 in metastatic site-derived aggressive cells reverted their metastatic potential both in vitro and in vivo. Conversely muting RD3 in neuroblastoma cells not only heightened invasion/migration but also dictated aggressive disease with metastasis. PMID: 26375249
    2. This study reports the results of an international study aimed at delineating the clinical and molecular spectrum of RD3 mutations in retinal dystrophies. PMID: 23308101
    3. Mutations in RD3 are a very rare cause of Leber's congenital amaurosis (LCA) associated with an extremely severe form of retinal dystrophy. PMID: 22531706
    4. RD3 suppresses the basal catalytic activity of guanylyl cyclase activating proteins (GCAP) in a noncompetitive manner. PMID: 21928830
    5. Identification and sequence analysis of C1orf36. PMID: 12914764
    6. the retinopathy-associated RD3 protein is part of subnuclear protein complexes involved in diverse processes, such as transcription and splicing. PMID: 17186464

    顯示更多

    收起更多

  • 相關疾病：
    Leber congenital amaurosis 12 (LCA12)
  • 亞細胞定位：
    Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment. Endosome. Nucleus. Cytoplasm. Cytoplasm, perinuclear region.
  • 組織特異性：
    Expressed in retina. Widely expressed (at protein level). In the retina the strongest immunoreactivity is detected in the inner half of the cytoplasmic portion of the photoreceptor layer, where rods and cones are found, and the external half of the outer
  • 數據庫鏈接：

    HGNC: 19689

    OMIM: 180040

    KEGG: hsa:343035

    STRING: 9606.ENSP00000355969

    UniGene: Hs.632495



主站蜘蛛池模板： 男女高潮喷水在线观看| 亚洲国产成人精品无码区在线| 国产一区二区三区影院| 国产午夜精品久久久久免费视| 伊人色综合久久天天网| 久久久www成人免费毛片| 免费无码精品黄av电影| 无码啪啪熟妇人妻区| 亚洲人成自拍网站在线观看| 亚洲色播爱爱爱爱爱爱爱| 亚洲人成网7777777国产| 国产成人精品a∨一区二区| 高h猛烈失禁潮喷无码视频| 337p日本欧洲亚洲大胆张筱雨| 国产精品美女久久久m| 亚洲无线观看国产精品| 国产乱人伦精品一区二区| 少妇人妻在线视频| 无码啪啪熟妇人妻区| 又爽又黄又无遮挡的激情视频免费| 欧美一区二区三区激情| 麻豆一区二区99久久久久 | 色欲一区二区三区精品a片| 精品人妻无码一区二区三区性| 日韩好精品视频你懂的| 亚洲精品乱码久久久久久日本麻豆| 欧美日韩免费专区在线| 亚洲乱码中文字幕综合| 奶头好大狂揉60分钟视频| 中文字幕久久久久人妻| 国产美女被遭高潮免费网站| 久久久亚洲欧洲日产国码606 | 黑人巨大av无码专区| 免费人成网站在线视频| 国产在线精品无码不卡手机免费| 丰满少妇弄高潮了www| 国产精品无码不卡一区二区三区| 久久久久久国产精品免费免费| 狠日狠干日日射| 天堂资源在线官网| 国产日产亚洲系列最新美使用方法 |