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RBBP9 Antibody

  • 中文名稱:
    RBBP9兔多克隆抗體
  • 貨號(hào):
    CSB-PA019394GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    RBBP9
  • 別名:
    B5T overexpressed gene protein antibody; B5T-overexpressed gene protein antibody; BOG antibody; Bog protein antibody; MGC9236 antibody; OTTHUMP00000030360 antibody; Protein BOG antibody; Putative hydrolase RBBP9 antibody; RBBP 10 antibody; RBBP 9 antibody; RBBP-10 antibody; RBBP-9 antibody; RBBP10 antibody; RBBP9 antibody; RBBP9_HUMAN antibody; Retinoblastoma binding protein 10 antibody; Retinoblastoma binding protein 9 antibody; Retinoblastoma-binding protein 10 antibody; Retinoblastoma-binding protein 9 antibody; Retinoma binding protein 9 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human RBBP9
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Serine hydrolase whose substrates have not been identified yet. May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation. May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1.
  • 基因功能參考文獻(xiàn):
    1. blood samples of lateral sclerosis patients were found to have significantly different levels of expression of CyFIP2 and RbBP9 compared to the levels of expression in control subjects. PMID: 22430187
    2. Structure- function studies of RBBP9 suggest possible routes for novel cancer drug discovery programs. PMID: 21933118
    3. Data identified RBBP4 and RBBP9 as required for maintenance of multiple PS cell types, and both RBBPs were bound to RB in PS cells. PMID: 21689726
    4. identify RBBP9 as a tumor-associated serine hydrolase that displays elevated activity in pancreatic carcinomas. RBBP9 promotes pancreatic carcinogenesis. PMID: 20080647
    5. RBBP10 was expressed widely in various human tissues, and the expression level is somewhat higher in tumor tissues than in normal tissues. PMID: 12296629
    6. The crystal structure of human RBBP9 has been determined at 1.72 A resolution by the seleno-methionyl single-wavelength anomalous diffraction method. PMID: 19004028

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  • 蛋白家族:
    RBBP9 family
  • 組織特異性:
    Expressed at higher levels in tumor tissues such as carcinoma.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 9892

    OMIM: 602908

    KEGG: hsa:10741

    STRING: 9606.ENSP00000336866

    UniGene: Hs.69330



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