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  4. RBBP9 Antibody, FITC conjugated

RBBP9 Antibody, FITC conjugated

  • 中文名稱：
    RBBP9兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA019394LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RBBP9 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RBBP9
  • 別名：
    B5T overexpressed gene protein antibody; B5T-overexpressed gene protein antibody; BOG antibody; Bog protein antibody; MGC9236 antibody; OTTHUMP00000030360 antibody; Protein BOG antibody; Putative hydrolase RBBP9 antibody; RBBP 10 antibody; RBBP 9 antibody; RBBP-10 antibody; RBBP-9 antibody; RBBP10 antibody; RBBP9 antibody; RBBP9_HUMAN antibody; Retinoblastoma binding protein 10 antibody; Retinoblastoma binding protein 9 antibody; Retinoblastoma-binding protein 10 antibody; Retinoblastoma-binding protein 9 antibody; Retinoma binding protein 9 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Putative hydrolase RBBP9 protein (1-186AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Serine hydrolase whose substrates have not been identified yet. May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation. May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1.
  • 基因功能參考文獻：
    1. blood samples of lateral sclerosis patients were found to have significantly different levels of expression of CyFIP2 and RbBP9 compared to the levels of expression in control subjects. PMID: 22430187
    2. Structure- function studies of RBBP9 suggest possible routes for novel cancer drug discovery programs. PMID: 21933118
    3. Data identified RBBP4 and RBBP9 as required for maintenance of multiple PS cell types, and both RBBPs were bound to RB in PS cells. PMID: 21689726
    4. identify RBBP9 as a tumor-associated serine hydrolase that displays elevated activity in pancreatic carcinomas. RBBP9 promotes pancreatic carcinogenesis. PMID: 20080647
    5. RBBP10 was expressed widely in various human tissues, and the expression level is somewhat higher in tumor tissues than in normal tissues. PMID: 12296629
    6. The crystal structure of human RBBP9 has been determined at 1.72 A resolution by the seleno-methionyl single-wavelength anomalous diffraction method. PMID: 19004028

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  • 蛋白家族：
    RBBP9 family
  • 組織特異性：
    Expressed at higher levels in tumor tissues such as carcinoma.
  • 數據庫鏈接：

    HGNC: 9892

    OMIM: 602908

    KEGG: hsa:10741

    STRING: 9606.ENSP00000336866

    UniGene: Hs.69330



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