在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RASA4 Antibody

RASA4 Antibody

  • 中文名稱：
    RASA4兔多克隆抗體
  • 貨號：
    CSB-PA957788
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA957788(RASA4 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    RASA4 antibody; CAPRI antibody; GAPL antibody; KIAA0538 antibody; Ras GTPase-activating protein 4 antibody; Calcium-promoted Ras inactivator antibody; Ras p21 protein activator 4 antibody; RasGAP-activating-like protein 2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human RASA4
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:10-1:50
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Ca(2+)-dependent Ras GTPase-activating protein, that switches off the Ras-MAPK pathway following a stimulus that elevates intracellular calcium. Functions as an adaptor for Cdc42 and Rac1 during FcR-mediated phagocytosis.
  • 基因功能參考文獻：
    1. RASA4 isoform 2 promoter methylation correlated with clinical parameters predicting poor prognosis (older age, elevated fetal hemoglobin), with higher risk of relapse after hematopoietic stem cell transplantation, and with PTPN11 mutation. PMID: 25147919
    2. Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities PMID: 21460216
    3. CAPRI seems to low-pass filter the Ca2+ signal, converting different intensities of stimulation into different durations of Ras activity. PMID: 16009725
    4. CAPRI (Ca2+-promoted Ras inactivator) a Ca2+-dependent Ras GTPase-activating protein (Ras GAP). Switches off the Ras-MAPK pathway following G protein-coupled receptor stimulated intracellular Ca2+ elevation that recruits CAPRI to the plasma membrane. PMID: 11448776
  • 亞細胞定位：
    Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Note=Localized to the cytosol as a result of its lack of phosphoinositide binding activity. Upon agonist-stimulated calcium mobilization, utilizes the C2A and C2B domains to associate with the plasma membrane.
  • 組織特異性：
    Widely expressed.
  • 數據庫鏈接：

    HGNC: 23181

    OMIM: 607943

    KEGG: hsa:10156

    STRING: 9606.ENSP00000262940

    UniGene: Hs.530089



主站蜘蛛池模板： 精品无码一区二区三区在线| 国产成人一区二区三区app| 免费人成在线观看| 国产性生交xxxxx免费| 日韩人妻无码精品一专区| 无码福利在线观看1000集| 国产成人无码a区在线观看视频 | 67pao国产成视频永久免费 | 免费无码av片流白浆在线观看| 久久精品九九热无码免贵| 97视频在线观看播放| 夜夜欢性恔免费视频| av第一福利网站| 男人的天堂在线视频 | 最近日本精品一卡2卡3卡4卡 | 欧美老妇乱辈通奷| 窝窝午夜色视频国产精品破| 少妇做爰免费视看片| 欧美 日产 国产在线观看| 国产亚洲精品a片久久久| 97碰碰碰人妻无码视频| 人妻精品久久久久中文字幕| 国产农村毛卡片| 日本黄页网站免费大全| 亚洲色欲一区二区三区在线观看| 亚洲女教师丝祙在线播放| 美女黄网站18禁免费看| 久久婷婷五月综合色国产| 少妇性l交大片7724com| 色综合亚洲一区二区小说| 亚洲欭美日韩颜射在线| 国产老妇伦国产熟女老妇视频| 国产高潮抽搐喷水高清| 97夜夜澡人人双人人人喊| 少妇激情一区二区三区视频小说| 久久人妻无码中文字幕| 无码精品日韩专区| 日本不卡一区二区三区| 国产午夜伦鲁鲁| 成年免费视频播放网站推荐| 日韩吃奶摸下aa片免费观看|