在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RASA4 Antibody

RASA4 Antibody

  • 中文名稱：
    RASA4兔多克隆抗體
  • 貨號：
    CSB-PA959950
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA959950(RASA4 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA959950(RASA4 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    RASA4 antibody; CAPRI antibody; GAPL antibody; KIAA0538 antibody; Ras GTPase-activating protein 4 antibody; Calcium-promoted Ras inactivator antibody; Ras p21 protein activator 4 antibody; RasGAP-activating-like protein 2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human RASA4
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:10-1:50
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Ca(2+)-dependent Ras GTPase-activating protein, that switches off the Ras-MAPK pathway following a stimulus that elevates intracellular calcium. Functions as an adaptor for Cdc42 and Rac1 during FcR-mediated phagocytosis.
  • 基因功能參考文獻：
    1. RASA4 isoform 2 promoter methylation correlated with clinical parameters predicting poor prognosis (older age, elevated fetal hemoglobin), with higher risk of relapse after hematopoietic stem cell transplantation, and with PTPN11 mutation. PMID: 25147919
    2. Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities PMID: 21460216
    3. CAPRI seems to low-pass filter the Ca2+ signal, converting different intensities of stimulation into different durations of Ras activity. PMID: 16009725
    4. CAPRI (Ca2+-promoted Ras inactivator) a Ca2+-dependent Ras GTPase-activating protein (Ras GAP). Switches off the Ras-MAPK pathway following G protein-coupled receptor stimulated intracellular Ca2+ elevation that recruits CAPRI to the plasma membrane. PMID: 11448776
  • 亞細胞定位：
    Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Note=Localized to the cytosol as a result of its lack of phosphoinositide binding activity. Upon agonist-stimulated calcium mobilization, utilizes the C2A and C2B domains to associate with the plasma membrane.
  • 組織特異性：
    Widely expressed.
  • 數據庫鏈接：

    HGNC: 23181

    OMIM: 607943

    KEGG: hsa:10156

    STRING: 9606.ENSP00000262940

    UniGene: Hs.530089



主站蜘蛛池模板： 人妻少妇无码中文幕久久| 日韩高清亚洲日韩精品一区| 久章草在线精品视频免费观看| 一本久道久久综合久久爱| 欧美性受xxxxzooz乱毛| 日本护士毛茸茸| 秋霞国产午夜伦午夜福利片| 伊人色综合网一区二区三区| 羞涩的丰满人妻40p| 国产丝袜美女| 日本乱妇乱子视频网站-百度| 亚洲 丝袜 制服 欧美 另类| 东京一本一道一二三区| 精产一二三产区m553| 麻豆精品国产精华精华液好用吗 | 亚洲欧美色αv在线影视| 久久久女人与动物群交毛片 | 色偷偷av亚洲男人的天堂 | 日韩人妻无码一区二区三区| 色欲av无码一区二区三区| 国产成人精品无码一区二区三区| 成人午夜亚洲精品无码区| 午夜福利视频| 男女啪啪做爰高潮免费网站| 一本到中文无码av在线精品| 又色又爽又黄的视频日本| 色八区人妻在线视频| 国内精品九九久久久精品| 麻豆精品偷拍人妻在线网址 | 亚洲精品制服丝袜四区| 欧美白人最猛性xxxxx| 狠狠噜天天噜日日噜| 丰满的人妻hd高清日本| 日韩精品一区二区大桥未久| 亚洲精品乱码久久久久久自慰| 狠狠躁夜夜躁av网站中文字幕| 亚洲爆乳无码专区www| 免费大片av手机看片不卡| 8888四色奇米在线观看| 一本色综合网久久| 新版天堂8中文在线最新版官网|