在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RAMP2 Antibody, FITC conjugated

RAMP2 Antibody, FITC conjugated

  • 中文名稱：
    RAMP2兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA019305LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) RAMP2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    RAMP2; Receptor activity-modifying protein 2; Calcitonin-receptor-like receptor activity-modifying protein 2; CRLR activity-modifying protein 2
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Receptor activity-modifying protein 2 protein (43-145AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL.
  • 基因功能參考文獻(xiàn)：
    1. Single nucleotide polymorphism of RAMP2 is associated with Stroke. PMID: 28904253
    2. This work suggests that RAMP2 may modify the agonist activity and trafficking of the GCGR, with potential relevance to production of new peptide analogs with selective agonist activities. PMID: 28586439
    3. Data suggest that a single GlcNAc residue at CTR N130 (asparagine 130) is responsible for enhanced affinity of calcitonin for CTR ECD; the same appears to apply for enhanced affinity of amylin for RAMP2-CTR ECD. [GlcNAc = N-acetylglucosamine; CTR = calcitonin receptor; ECD = extracellular domain; RAMP2 = receptor (calcitonin) activity modifying protein 2]. PMID: 28614667
    4. This study reveals the glucagon receptor as a previously unidentified target for GLP-1 receptor agonists and highlights a role for RAMP2 in regulating its pharmacology. PMID: 26198634
    5. Adrenomedullin-RAMP2 system suppresses ER stress-induced tubule cell death and is involved in kidney protection. PMID: 24505304
    6. Data suggest isoforms of RAMP modulate accessibility of peptides to residues situated on CALCRL (calcitonin receptor-like receptor) N-terminal domain; RAMP3/RAMP2/RAMP1 appear to alter accessibility of specific residues at CALCRL-RAMP interface. PMID: 24199627
    7. RAMP2 gene expression increases with gestational age development in the fetal lung. PMID: 24169318
    8. Co-expression of calcitonin receptors (CT) lacking a portion of domain 1 with receptor activity-modifying protein (RAMP) 1, 2, or 3 appears to produce functional CT-(8-32)-sensitive adrenomedullin receptors. PMID: 12565884
    9. TNF-alpha induced time- and dose-dependent decreases in the expression of RAMP2 mRNA in cultured human coronary artery smooth muscle cells , thereby diminishing AM-evoked cAMP production PMID: 15245870
    10. Data found that expressions of RAMP1, RAMP2 and RAMP3 mRNAs increased with the worsening of heart function, but the expressions of RAMP1 and RAMP2 mRNA decreased at level IV of heart failure. PMID: 15300632
    11. adrenomedullin receptors are comprised of RAMP2 and calcitonin receptor-like receptor. PMID: 15613468
    12. This study reveals important functionality of the RAMP C-terminal domain and identifies key differences in the role of the RAMP C terminus for calcitonin receptor versus calcitonin receptor-like receptor-based receptors. PMID: 16912219
    13. RAMP2 is silenced by promoter hypermethylation in lung cancer PMID: 17671114
    14. Identification of RAMP2 residues for adrenomedullin receptors are reported. PMID: 18593822
    15. The His residues of hRAMP2 and -3 differentially govern adrenomedullin receptor function. PMID: 18835256

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    RAMP family
  • 組織特異性：
    Strongly expressed in lung, breast, immune system and fetal tissues.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 9844

    OMIM: 605154

    KEGG: hsa:10266

    STRING: 9606.ENSP00000253796

    UniGene: Hs.514193



主站蜘蛛池模板： 成在人线av无码免观看| 欧美奶涨边摸边做爰视频| 久久久精品中文字幕麻豆发布| 国内精品久久久久久影院| 免费国产成人午夜福利电影| a毛片终身免费观看网站| 欧美国产一区二区三区激情无套| 国产精品成人久久电影| 国产熟妇另类久久久久久| av色综合久久天堂av色综合| 男女一边摸一边做爽爽| 日韩乱码人妻无码系列中文字幕| 成+人+网+站+免费观看| 国产一卡二卡三卡四卡视频版| 色鬼7777久久| 99视频精品国产免费观看 | 手机看片精品国产福利| 香蕉久久精品日日躁夜夜躁夏| 无遮挡边摸边吃奶边做视频| 亚洲香蕉aⅴ视频在线播放| 免费又黄又爽又猛的毛片| 免费看欧美成人a片无码| 四虎影视久久久免费观看 | 麻豆视传媒官网免费观看| 国内精品久久久久久tv| 亚洲级αv无码毛片久久精品| 337p亚洲日本中国大胆69| 免免费国产aaaaa片| 人妻久久久一区二区三区| 狼人亚洲国内精品自在线| 夜色爽爽影院18禁妓女影院| 国产综合无码一区二区色蜜蜜| 少妇无码av无码专区线| 亚洲国产老鸭窝一区二区三区| 午夜成人理论无码电影在线播放 | 久久人妻国产精品31| 国产伦孑沙发午休精品| 一本一道精品欧美中文字幕| 性欧美videofree高清精品| 欧洲lv尺码大精品久久久| 人妻少妇偷人精品无码|