在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RABEP1 Antibody

RABEP1 Antibody

  • 中文名稱：
    RABEP1兔多克隆抗體
  • 貨號：
    CSB-PA614886LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate, 293T whole cell lysate, SH-SY5Y whole cell lysate, HepG2 whole cell lysate, 293 whole cell lysate, A549 whole cell lysate
      All lanes: RABEP1 antibody at 1:2500
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 100, 96 kDa
      Observed band size: 100 kDa
    • IHC image of CSB-PA614886LA01HU diluted at 1:300 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RABEP1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    RABEP1 antibody; RAB5EP antibody; RABPT5 antibody; RABPT5A antibody; Rab GTPase-binding effector protein 1 antibody; Rabaptin-4 antibody; Rabaptin-5 antibody; Rabaptin-5alpha antibody; Renal carcinoma antigen NY-REN-17 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Rab GTPase-binding effector protein 1 protein (1-255AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，RABEP1 Antibody (CSB-PA614886LA01HU)，的標記方式是Non-conjugated。對于RABEP1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA614886LB01HU RABEP1 Antibody, HRP conjugated ELISA
    FITC CSB-PA614886LC01HU RABEP1 Antibody, FITC conjugated
    Biotin CSB-PA614886LD01HU RABEP1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:200-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. Mediates the traffic of PKD1:PKD2 complex from the endoplasmic reticulum through the Golgi to the cilium.
  • 基因功能參考文獻：
    1. SH2B1 and RABEP1 genetic variants are associated with worsening of LDL and glucose parameters in patients treated with psychotropic drugs PMID: 28694205
    2. The results contradict the model of feedback activation of Rab5 and instead indicate that Rbpt5 is recruited by both Rabex5 recognizing ubiquitylated cargo and by Rab4 to activate Rab5 in a feed-forward manner. PMID: 26430212
    3. ITSN2L interacts with RABEP1 and stimulates its degradation in regulation of endocytosis. PMID: 26633357
    4. The pleckstrin homology domain (PH) of PLD1 itself promotes degradation of HIF-1alpha, then accelerates EGFR endocytosis via upregulation of rabaptin-5 and suppresses tumor progression. PMID: 26680696
    5. analysis of Rabex-5 GEF activation by Rabaptin-5 PMID: 24957337
    6. The disruption of Rabaptin-5 Ser407 phosphorylation reduces persistent cell migration in 2D and alphavbeta3-dependent invasion. PMID: 22975325
    7. Silencing of Rabaptin-5 induces down-regulation of recycling of K(V)10.1 channel in transfected cells and reduction of K(V)10.1 current density in cells natively expressing K(V)10.1, indicating a role of Rabaptin-5 in channel trafficking. PMID: 22841712
    8. Breast cancer cell line studies showed that microRNA, miR-373, was capable of promoting breast cancer invasion and metastasis via translational inhibition of TXNIP and RABEP1 that were the direct target genes of miR-373. PMID: 21271679
    9. GGAs, a family of Arf-dependent clathrin adaptors involved in selection of TGN cargo, interact with the Rabaptin-5-Rabex-5 complex, a Rab4/Rab5 effector regulating endosome fusion PMID: 12505986
    10. The authors determined that increased listeriolysin O-independent dissolution of vacuoles during RABEP1 knockdown required the Listeria monocytogenes broad-range phospholipase C (PC-PLC). PMID: 19500109

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Early endosome. Recycling endosome. Cytoplasmic vesicle.
  • 蛋白家族：
    Rabaptin family
  • 數據庫鏈接：

    HGNC: 17677

    OMIM: 603616

    KEGG: hsa:9135

    STRING: 9606.ENSP00000262477

    UniGene: Hs.584784



主站蜘蛛池模板： 日本一区午夜艳熟免费| 欧美成aⅴ人高清免费| 国内精品无码一区二区三区| 国产欧美亚洲精品a第一页| 高潮毛片无遮挡高清免费| 免费男人下部进女人下部视频| 在线视频 亚太 国产 欧美 一区二区| 亚洲精品无码少妇30p| 免费看欧美成人a片无码| 成年女人a毛片免费视频| 亚洲性无码一区二区三区| 无码人妻少妇精品无码专区漫画 | 欧洲-级毛片内射| 久久三级中文欧大战字幕| 中国大陆精品视频xxxx| 欧洲吸奶大片在线看| 欧美亚洲偷图色综合| 亚洲成av人片在线观看橙子| 国产成人无码一区二区在线播放| 人人妻在人人| 国产第一页浮力影院入口| 国产成人午夜福利免费无码r| 无码人妻少妇色欲av一区二区| 久久久无码人妻精品一区| 亚洲 自拍 色综合图区av| 亚欧av无码乱码在线观看性色| 九九九免费观看视频| 国产一区二区三区 韩国女主播| 国产精品视频色拍在线视频| 久久人人爽人人爽人人片av高清| 久久精品丝袜高跟鞋| 亚洲精品久久yy5099| 亚洲中文字幕无码乱线| 国产一区二区波多野结衣| 小12萝裸体视频国产| 2022一本久道久久综合狂躁| 99久久婷婷国产综合精品青草免费| 99er国产这里只有精品视频免费| 97热久久免费频精品99| 亚洲精品中文字幕乱码| 四虎影视国产精品久久|