在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

RABEP1 Antibody

  • 中文名稱:
    RABEP1兔多克隆抗體
  • 貨號:
    CSB-PA019228GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    RABEP1 antibody; RAB5EP antibody; RABPT5 antibody; RABPT5A antibody; Rab GTPase-binding effector protein 1 antibody; Rabaptin-4 antibody; Rabaptin-5 antibody; Rabaptin-5alpha antibody; Renal carcinoma antigen NY-REN-17 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human RABEP1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. Mediates the traffic of PKD1:PKD2 complex from the endoplasmic reticulum through the Golgi to the cilium.
  • 基因功能參考文獻:
    1. SH2B1 and RABEP1 genetic variants are associated with worsening of LDL and glucose parameters in patients treated with psychotropic drugs PMID: 28694205
    2. The results contradict the model of feedback activation of Rab5 and instead indicate that Rbpt5 is recruited by both Rabex5 recognizing ubiquitylated cargo and by Rab4 to activate Rab5 in a feed-forward manner. PMID: 26430212
    3. ITSN2L interacts with RABEP1 and stimulates its degradation in regulation of endocytosis. PMID: 26633357
    4. The pleckstrin homology domain (PH) of PLD1 itself promotes degradation of HIF-1alpha, then accelerates EGFR endocytosis via upregulation of rabaptin-5 and suppresses tumor progression. PMID: 26680696
    5. analysis of Rabex-5 GEF activation by Rabaptin-5 PMID: 24957337
    6. The disruption of Rabaptin-5 Ser407 phosphorylation reduces persistent cell migration in 2D and alphavbeta3-dependent invasion. PMID: 22975325
    7. Silencing of Rabaptin-5 induces down-regulation of recycling of K(V)10.1 channel in transfected cells and reduction of K(V)10.1 current density in cells natively expressing K(V)10.1, indicating a role of Rabaptin-5 in channel trafficking. PMID: 22841712
    8. Breast cancer cell line studies showed that microRNA, miR-373, was capable of promoting breast cancer invasion and metastasis via translational inhibition of TXNIP and RABEP1 that were the direct target genes of miR-373. PMID: 21271679
    9. GGAs, a family of Arf-dependent clathrin adaptors involved in selection of TGN cargo, interact with the Rabaptin-5-Rabex-5 complex, a Rab4/Rab5 effector regulating endosome fusion PMID: 12505986
    10. The authors determined that increased listeriolysin O-independent dissolution of vacuoles during RABEP1 knockdown required the Listeria monocytogenes broad-range phospholipase C (PC-PLC). PMID: 19500109

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Early endosome. Recycling endosome. Cytoplasmic vesicle.
  • 蛋白家族:
    Rabaptin family
  • 數據庫鏈接:

    HGNC: 17677

    OMIM: 603616

    KEGG: hsa:9135

    STRING: 9606.ENSP00000262477

    UniGene: Hs.584784



主站蜘蛛池模板: 国产精品久久久久影院老司| 欧美成人精品 一区二区三区| 特黄做受又粗又长又大又硬| 亚洲成在线aⅴ免费视频| 亚洲午夜未满十八勿入| 国产精品亚韩精品无码a在线| 国产后入清纯学生妹| 国语自产拍精品香蕉在线播放| 青青草国产免费久久久下载| 国产成人av综合色| 国产av麻豆mag剧集| 日日橹狠狠爱欧美视频| 成人亚洲a片v一区二区三区动漫| 伊人久久精品一区二区三区| 香蕉人妻av久久久久天天| 日韩人妻无码精品专区906188| 亚洲全部无码中文字幕| 欧美人妻一区二区三区| 欧美人与动牲交xxxxbbbb| 成年男人裸j照无遮挡无码| 久久久久四虎精品免费入口| 亚洲国产欧美在线人成app| 麻花传媒在线mv免费观看视频| 午夜免费福利小电影| 国产成 人 综合 亚洲网站| 人妻av无码专区| 亚洲熟妇无码av在线播放| 2012中文字幕在线视频| 亚洲欧美日韩_欧洲日韩| 亚洲成av人片一区二区梦乃| 国产毛a片啊久久久久久保和丸| 火箭视频在线观看精品| 久久不见久久见免费影院视频| 蜜桃视频无码区在线观看| 人妻少妇heyzo无码专区| 中文字幕奈奈美被公侵犯| 女人扒开屁股爽桶30分钟| 国产成a人片在线观看视频下载| 国产在线视频天天综合网| 99精品视频免费热播在线观看| 国产成人麻豆亚洲综合无码精品|