在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RAB31 Antibody

RAB31 Antibody

  • 中文名稱：
    RAB31兔多克隆抗體
  • 貨號：
    CSB-PA019183GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    Rab 22B antibody; RAB 31 antibody; Rab22B antibody; Rab31 antibody; RAB31 member RAS oncogene family antibody; RAB31_HUMAN antibody; Ras related protein Rab 31 antibody; Ras related protein Rab31 antibody; Ras-related protein Rab-22B antibody; Ras-related protein Rab-31 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human RAB31
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:1000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane. Plays a role in M6PR transport from the trans-Golgi network to endosomes. Plays a role in the internalization of EGFR from the cell membrane into endosomes. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.
  • 基因功能參考文獻：
    1. the role of Rab31 in cancer progression, is reported. PMID: 26245486
    2. this study provides the evidence of Rab31 overexpression in HCC, and Rab31 is potentially used as a novel biomarker of poor prognosis in patients with HCC. PI3K/AKT/Bcl-2/BAX axis was involved in Rab31-promoting HCC progression. PMID: 26044564
    3. Data indicate that early endosome antigen 1 (EEA1) is important for the small GTPase Rab31-mediated enhancement of ligand-bound EGF receptor (EGFR) endocytic trafficking. PMID: 24644286
    4. MUC1-C and Rab31 function in an autoinductive loop that contributes to overexpression of MUC1-C in breast cancer cells. PMID: 22792175
    5. Overexpression of rab31 in breast cancer cells leads to a switch from an invasive to a proliferative phenotype as indicated by an increased cell proliferation, reduced adhesion and invasion in vitro, and a reduced capacity to form lung metastases in vivo. PMID: 22920728
    6. Neither UPARwt, nor UPAR-del4/5 nor RAB31 mRNA expression levels were found to be prognostic markers in advanced ovarian cancer. PMID: 21848504
    7. RIN3 specifically acts as a GEF for Rab31. PMID: 21586568
    8. Thus, Rab22B may have a role in anterograde exit from the trans-Golgi network . PMID: 17678623
    9. uPAR-del4/5 and rab31 mRNA represent independent prognostic markers in breast cancer and may be components of different, but possibly associated, tumor-relevant signaling pathways. PMID: 17952591
    10. Rab22B possibly plays role in regulating epidermal growth factor receptor (EGFR) and mannose 6-phosphate receptor (M6PR) transport into late endosomes. PMID: 19725050

    顯示更多

    收起更多

  • 亞細胞定位：
    Golgi apparatus, trans-Golgi network. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor; Cytoplasmic side. Early endosome. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 組織特異性：
    Highest expression in placenta and brain with lower levels in heart and lung. Not detected in liver, skeletal muscle, kidney or pancreas.
  • 數據庫鏈接：

    HGNC: 9771

    OMIM: 605694

    KEGG: hsa:11031

    STRING: 9606.ENSP00000304565

    UniGene: Hs.744887



主站蜘蛛池模板： 欧美成a人片在线观看久| 蜜臀av网站在线| 精品无人乱码高清| 亚洲6080yy久久无码产自国产 | 啦啦啦www在线观看免费视频| 国产精品186在线观看在线播放| 国产精品亚洲一区二区无码| 99久久免费国产精品四虎| 成人国产精品秘片多多| 国产午夜福利在线观看视频| 777精品出轨人妻国产| 色综合天天天天综合狠狠爱| 亚洲无线卡一卡二| 人妻精品无码一区二区三区| 少妇的丰满3中文字幕| 亚洲 一区二区 在线| 少妇激情一区二区三区视频| 初尝人妻少妇中文字幕| 亚洲精品无码av中文字幕电影网站 | 超碰97久久国产精品牛牛| 国产精品久久久久久久久久久不卡| 三上悠亚的av片在线无码| 亚洲精品无码专区在线| 一本加勒比波多野结衣| 亚洲精品成人无限看| 精品婷婷色一区二区三区| 欧美综合区自拍亚洲综合绿色 | av无码久久久久久不卡网站| 亚洲免费网站观看视频| 2020无码天天喷水天天爽| 在线播放五十路熟妇| 亚洲中文字幕乱码av波多ji| 亚洲自偷自偷偷色无码中文| 久久婷婷五月综合97色一本一本 | 国内精品久久久久影院老司机| 国产精品av一区二区三区不卡蜜| 手机福利视频| 在线无码中文字幕一区| 国产无遮挡又黄又爽动态图| 欧美黑人乱大交| 国产又色又爽又刺激视频|