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RAB20 Antibody

  • 中文名稱：
    RAB20兔多克隆抗體
  • 貨號：
    CSB-PA173917
  • 規格：
    ￥1100
  • 圖片：
    • Gel: 12%SDS-PAGE,Lysate: 40 μg,,Primary antibody: CSB-PA173917(RAB20 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 30 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    RAB20
  • 別名：
    FLJ20429 antibody; RAB20 antibody; RAB20 member RAS oncogene family antibody; RAB20_HUMAN antibody; Ras related protein Rab20 antibody; Ras-related protein Rab-20 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Full length fusion protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.
  • 基因功能參考文獻：
    1. Rab20 is specifically and significantly upregulated in the sputum of human patients with active tuberculosis. PMID: 28494243
    2. TdIF1 associates with the RAB20 promoter, and RAB20 gene transcription is reduced in TdIF1-knocked-down cells, suggesting that TdIF1 stimulates RAB20 gene transcription. PMID: 23874396
    3. Regulates connexin 43 intracellular transport. PMID: 18649179
  • 亞細胞定位：
    Golgi apparatus. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 組織特異性：
    Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level).
  • 數據庫鏈接：

    HGNC: 18260

    KEGG: hsa:55647

    STRING: 9606.ENSP00000267328

    UniGene: Hs.743563



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