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  4. RAB20 Antibody, FITC conjugated

RAB20 Antibody, FITC conjugated

  • 中文名稱：
    RAB20兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA878910LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RAB20 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RAB20
  • 別名：
    FLJ20429 antibody; RAB20 antibody; RAB20 member RAS oncogene family antibody; RAB20_HUMAN antibody; Ras related protein Rab20 antibody; Ras-related protein Rab-20 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Ras-related protein Rab-20 protein (1-234AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.
  • 基因功能參考文獻：
    1. Rab20 is specifically and significantly upregulated in the sputum of human patients with active tuberculosis. PMID: 28494243
    2. TdIF1 associates with the RAB20 promoter, and RAB20 gene transcription is reduced in TdIF1-knocked-down cells, suggesting that TdIF1 stimulates RAB20 gene transcription. PMID: 23874396
    3. Regulates connexin 43 intracellular transport. PMID: 18649179
  • 亞細胞定位：
    Golgi apparatus. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 組織特異性：
    Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level).
  • 數據庫鏈接：

    HGNC: 18260

    KEGG: hsa:55647

    STRING: 9606.ENSP00000267328

    UniGene: Hs.743563



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