在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. Pdgfd Antibody, FITC conjugated

Pdgfd Antibody, FITC conjugated

  • 中文名稱：
    Pdgfd兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA852889LC01MO
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Mus musculus (Mouse) Pdgfd Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Pdgfd antibody; Scdgfb antibody; Platelet-derived growth factor D antibody; PDGF-D antibody; Spinal cord-derived growth factor B antibody; SCDGF-B) [Cleaved into: Platelet-derived growth factor D antibody; latent form antibody; PDGFD latent form); Platelet-derived growth factor D antibody; receptor-binding form antibody; PDGFD receptor-binding form)] antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Mouse
  • 免疫原：
    Recombinant Mouse Platelet-derived growth factor D protein (24-370AA)
  • 免疫原種屬：
    Mus musculus (Mouse)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Has oncogenic potential and can induce tumor formation. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix.
  • 基因功能參考文獻：
    1. Data (including data from studies using transgenic/mutant mice and cells from such mice) suggest that Pdgfd promotes cell proliferation, cell migration, and expression of inflammatory factors in adventitial fibroblasts; in obese mice, inhibition of Pdgfd significantly reduces aortic aneurysm formation (induced by infusion of angiotensin II). PMID: 29794241
    2. upregulated in kidney fibrosis, may mediate renal scarring, and is dispensable for normal kidney development and physiological functions PMID: 26924050
    3. Inactivation of the Pdgfd gene resulted in a mild phenotype in C57BL/6 mice, and the offspring was viable, fertile and generally in good health. PMID: 27032083
    4. PDGF-D intensifies fibrogenesis by interfering with the fibrolytic activity of the TIMP-1/MMP-2/MMP-9 system, and PDGF-D signaling is mediated through both PDGF-alpha and -beta receptors. PMID: 25576870
    5. Radial glia require PDGFD-PDGFRbeta signalling in human but not mouse neocortex PMID: 25391964
    6. PDGF D represents a potentially promising target for prostate carcinoma treatment resistance in the absence of PTEN function, and warrants further laboratory evaluation and clinical study. PMID: 24331662
    7. Data indicate that the proteolytic processing of full-length PDGF-D is required for PDGF-D activation of preosteoclasts, and that beta-PDGFR is present in activated osteoclasts. PMID: 22158043
    8. identified PDGF-DD as an important target gene for antiangiogenic therapy due to its pleiotropic effects on vascular and non-vascular cells. PDGF-DD inhibition may offer new therapeutic options to treat neovascular diseases PMID: 20231273
    9. Failure of laminin alpha4-mediated down-regulation of PDGF activity contributes to the progressive renal lesions in this animal model. PMID: 20035058
    10. These results suggest that PDGF-D induce cellular transformation and promote tumour growth by accelerating the proliferation rate of the tumour cells, and by stimulation of tumour neovascularization. PMID: 12629513
    11. splicing variant results in significant differences in peptide expression and function PMID: 12890490
    12. PDGF-D plays an important role in the pathogenesis of tubulointerstitial injury through binding of PDGF-Rbeta in obstructive ureteral nephropathy PMID: 14514732
    13. PDGF-DD, a novel mediator of smooth muscle cell phenotypic modulation, is upregulated in endothelial cells exposed to atherosclerosis-prone flow patterns. PMID: 19028801

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    PDGF/VEGF growth factor family
  • 組織特異性：
    Expressed at high levels in developing heart, lung, kidney and some muscle derivatives. Moderately expressed in liver, brain and testis. In the kidney, localized to glomerular mesangial cells and vascular smooth muscle cells. Up-regulated in areas of rena
  • 數據庫鏈接：


主站蜘蛛池模板： 动漫无遮挡h纯肉亚洲资源大片| 一性一交一口添一摸视频| 国产精品你懂的在线播放| 欧美日韩一区二区三区自拍| 欧美品无码一区二区三区在线蜜桃| 无码东京热一区二区三区| 亚洲第一a在线观看网站| 精品无人码麻豆乱码1区2区 | 永久免费看mv网站入口亚洲| 亚洲性av免费| 亚洲精品午夜理伦不卡在线观看| 军人粗大的内捧猛烈进出视频| 色婷婷综合久久久中文字幕| 中文字幕日本人妻久久久免费| 精品视频一区二区三三区四区 | 国产成人亚洲精品狼色在线| 日韩综合亚洲色在线影院| 800av凹凸视频在线观看| 亚洲中文字幕无码久久2017| 尤物视频在线观看| av无码国产精品麻豆| 国产极品久久久久久久久| 人妻av综合天堂一区| 日韩欧美亚洲综合久久| 日本丰满熟妇bbxbbxhd| 久久亚洲精品无码爱剪辑| 色欲香天天综合网站| 国产精品毛片久久久久久久| 亚洲国色天香卡2卡3卡4| 香蕉97超级碰碰碰视频| 国产播放隔着超薄丝袜进入| 欧美人与动牲猛交a欧美精品| 欧美性xxxx狂欢老少配| 国产精品人妻久久毛片高清无卡| 无码一卡二卡三卡四卡| 制服丝袜另类专区制服| 日本强好片久久久久久aaa| 一边捏奶头一边啪高潮视频 | 无人去码一码二码三码区| 国产精品宾馆在线精品酒店| 成人区精品一区二区婷婷 |