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  4. PTGR2 Antibody

PTGR2 Antibody

  • 中文名稱：
    PTGR2兔多克隆抗體
  • 貨號：
    CSB-PA007365
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of K562 cells using PTGR2 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    PTGR2
  • 別名：
    15 oxoprostaglandin 13 reductase antibody; 15 oxoprostaglandin delta 13 reductase antibody; 15-oxoprostaglandin 13-reductase antibody; DKFZp686P10120 antibody; FLJ39091 antibody; FLJ99229 antibody; PGR 2 antibody; PGR2 antibody; PRG-2 antibody; Prostaglandin reductase 2 antibody; PTGR 2 antibody; PTGR2 antibody; PTGR2_HUMAN antibody; Zinc binding alcohol dehydrogenase domain containing 1 antibody; Zinc binding alcohol dehydrogenase domain containing protein 1 antibody; Zinc-binding alcohol dehydrogenase domain-containing protein 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human PTGR2.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:10000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation.
  • 基因功能參考文獻：
    1. Silencing of PTGR2 expression enhances reactive oxygen species production, suppresses pancreatic cell proliferation, and promotes cell death through increasing 15-keto-PGE2. PMID: 26820738
    2. Functional data and clinical relevance for the role of PTGR2 in gastric cancer, are provided. PMID: 22998775
    3. Cloning and tissue distribution of a splicing variant ZADH1b. PMID: 15004468
    4. Besides targeting cyclooxygenase, indomethacin inhibits PTGR2 with a binding mode similar to that of 15-keto-PGE(2). PMID: 19000823
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    NADP-dependent oxidoreductase L4BD family
  • 組織特異性：
    Widely expressed.
  • 數據庫鏈接：

    HGNC: 20149

    OMIM: 608642

    KEGG: hsa:145482

    STRING: 9606.ENSP00000267568

    UniGene: Hs.632344



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