在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PTBP2 Antibody

  • 中文名稱:
    PTBP2兔多克隆抗體
  • 貨號:
    CSB-PA018950GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    brPTB antibody; FLJ34897 antibody; MIBP antibody; Neural polypyrimidine tract binding protein antibody; Neural polypyrimidine tract-binding protein antibody; Neurally enriched homolog of PTB antibody; Neurally-enriched homolog of PTB antibody; nPTB 5 antibody; nPTB 6 antibody; nPTB 7 antibody; nPTB 8 antibody; nPTB antibody; nPTB5 antibody; nPTB6 antibody; nPTB7 antibody; nPTB8 antibody; Polypyrimidine tract binding protein 2 antibody; Polypyrimidine tract-binding protein 2 antibody; PTB antibody; PTB like antibody; PTB like protein antibody; PTB-like protein antibody; PTBLP antibody; PTBP 2 antibody; Ptbp2 antibody; PTBP2_HUMAN antibody; Splicing regulator antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human PTBP2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation.; Reduced affinity for RNA.
  • 基因功能參考文獻:
    1. It has been established that PTBP1 and PTBP2 are members of a family of cryptic exon repressors. PMID: 27681424
    2. PTBP1 and PTBP2 impaired autoregulation of SRSF3 in oral squamous cell carcinoma cancer cells. PMID: 26416554
    3. Data show that polypyrimidine tract-binding proteins nPTB and ROD1 interact with mitochondrial tRNA(Thr) in the cytoplasm outside of mitochondria. PMID: 26657638
    4. In T98G glioma cells, the level of sumoylated PTBP2 was reduced compared to that of normal brain cells. Overall, this study shows that PTBP2 is posttranslationally modified by SUMO1. PMID: 24286314
    5. MALAT1 binds to SFPQ releasing PTBP2 from the SFPQ/PTBP2 complex, the increased SFPQ-detached PTBP2 promotes cell proliferation and migration in colorectal cancer. PMID: 25025966
    6. Defining the multifunctional roles of PTB will contribute to the understanding of key regulatory events in gene expression. PMID: 24264039
    7. Changes in miR-223/PTBP2 pathway could contribute of abnormal splicing in chronic myeloid leukemia. PMID: 23174904
    8. Regulation of the mutually exclusive exons 8a and 8 in the CaV1.2 calcium channel transcript by polypyrimidine tract-binding protein. PMID: 21282112
    9. present fluorescence, NMR, and in vivo splicing data in support of a role of PTB in inducing RNA loops. We show that the RNA recognition motifs (RRMs) 3 and 4 of PTB can bind two distant pyrimidine tracts and bring their 5' and 3' ends in close proximity PMID: 20160105
    10. The nPTB proximal promoter, although rich in G+C content and presenting putative binding sites for the transcription factors Sp1, NF-1, NF-kB and Oct-1, lacks a typical TATA box. PMID: 16002244
    11. Study shows that PTB can function as an anti-repressor molecule to counteract the splicing inhibitory activity of SRp30c. PMID: 17548433

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 組織特異性:
    Mainly expressed in brain although also detected in other tissues like heart and skeletal muscle. Isoform 1 and isoform 2 are specifically expressed in neuronal tissues. Isoform 3 and isoform 4 are expressed in non-neuronal tissues. Isoform 5 and isoform
  • 數據庫鏈接:

    HGNC: 17662

    OMIM: 608449

    KEGG: hsa:58155

    STRING: 9606.ENSP00000412788

    UniGene: Hs.596061



主站蜘蛛池模板: 日本熟妇hdsex视频| 国产明星xxxx色视频| 18禁无遮挡肉动漫在线播放观看| 国产在线高清视频无码| av在线 亚洲 天堂| 中文字幕人妻熟女人妻| 国产激情艳情在线看视频| 色护士极品影院| 亚洲香蕉视频天天爽| 国精品午夜福利视频| 太深太粗太爽太猛了视频免费观看| 国产大陆亚洲精品国产| 成年女人免费视频播放体验区 | 欧美成人va免费看视频| 97久久婷婷五月综合色d啪蜜芽| 国产亚洲精品久久久久久禁果tv | 免费看少妇作爱视频| 爆乳熟妇一区二区三区| 丁香婷婷激情综合俺也去| 性中国妓女毛茸茸视频| 粉嫩大学生无套内射无码卡视频 | 国产精品免费视频网站| 国产精品调教视频一区| 一二三四社区在线中文视频| 精精国产xxxx视频在线播放| 99国产精品久久久久久久成人| 天天澡天天揉揉av在线| 青草草97久热精品视频| 成人av无码国产在线观看| 中文字幕人妻无码视频| 亚洲午夜精品a片久久www慈禧| 国产99视频精品专区| 天天天天噜在线视频| 无码人妻丰满熟妇区bbbbxxxx| 亚洲天堂男人影院| 337人体做爰大胆视频| 国产精品一国产精品一k频道| 国产一卡二卡三新区2022| 男人猛吃奶女人爽视频| 国产成人免费ā片在线观看| 人妻丰满熟妇a无码区|