在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PTBP2 Antibody, Biotin conjugated

  • 中文名稱:
    PTBP2兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA892133LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PTBP2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    brPTB antibody; FLJ34897 antibody; MIBP antibody; Neural polypyrimidine tract binding protein antibody; Neural polypyrimidine tract-binding protein antibody; Neurally enriched homolog of PTB antibody; Neurally-enriched homolog of PTB antibody; nPTB 5 antibody; nPTB 6 antibody; nPTB 7 antibody; nPTB 8 antibody; nPTB antibody; nPTB5 antibody; nPTB6 antibody; nPTB7 antibody; nPTB8 antibody; Polypyrimidine tract binding protein 2 antibody; Polypyrimidine tract-binding protein 2 antibody; PTB antibody; PTB like antibody; PTB like protein antibody; PTB-like protein antibody; PTBLP antibody; PTBP 2 antibody; Ptbp2 antibody; PTBP2_HUMAN antibody; Splicing regulator antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Polypyrimidine tract-binding protein 2 protein (13-289AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation.; Reduced affinity for RNA.
  • 基因功能參考文獻:
    1. It has been established that PTBP1 and PTBP2 are members of a family of cryptic exon repressors. PMID: 27681424
    2. PTBP1 and PTBP2 impaired autoregulation of SRSF3 in oral squamous cell carcinoma cancer cells. PMID: 26416554
    3. Data show that polypyrimidine tract-binding proteins nPTB and ROD1 interact with mitochondrial tRNA(Thr) in the cytoplasm outside of mitochondria. PMID: 26657638
    4. In T98G glioma cells, the level of sumoylated PTBP2 was reduced compared to that of normal brain cells. Overall, this study shows that PTBP2 is posttranslationally modified by SUMO1. PMID: 24286314
    5. MALAT1 binds to SFPQ releasing PTBP2 from the SFPQ/PTBP2 complex, the increased SFPQ-detached PTBP2 promotes cell proliferation and migration in colorectal cancer. PMID: 25025966
    6. Defining the multifunctional roles of PTB will contribute to the understanding of key regulatory events in gene expression. PMID: 24264039
    7. Changes in miR-223/PTBP2 pathway could contribute of abnormal splicing in chronic myeloid leukemia. PMID: 23174904
    8. Regulation of the mutually exclusive exons 8a and 8 in the CaV1.2 calcium channel transcript by polypyrimidine tract-binding protein. PMID: 21282112
    9. present fluorescence, NMR, and in vivo splicing data in support of a role of PTB in inducing RNA loops. We show that the RNA recognition motifs (RRMs) 3 and 4 of PTB can bind two distant pyrimidine tracts and bring their 5' and 3' ends in close proximity PMID: 20160105
    10. The nPTB proximal promoter, although rich in G+C content and presenting putative binding sites for the transcription factors Sp1, NF-1, NF-kB and Oct-1, lacks a typical TATA box. PMID: 16002244
    11. Study shows that PTB can function as an anti-repressor molecule to counteract the splicing inhibitory activity of SRp30c. PMID: 17548433

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 組織特異性:
    Mainly expressed in brain although also detected in other tissues like heart and skeletal muscle. Isoform 1 and isoform 2 are specifically expressed in neuronal tissues. Isoform 3 and isoform 4 are expressed in non-neuronal tissues. Isoform 5 and isoform
  • 數據庫鏈接:

    HGNC: 17662

    OMIM: 608449

    KEGG: hsa:58155

    STRING: 9606.ENSP00000412788

    UniGene: Hs.596061



主站蜘蛛池模板: 欧美激情精品成人一区| 亚洲精品高清国产一久久| 国产精品特黄aaaa片在线观看 | 久久www成人看片免费不卡| 国产成人亚洲精品无码车a| 免费视频爱爱太爽了网站| 国产精品麻豆成人av电影艾秋| 欧美老妇与禽交| 成人性生交大片免费看r链接| 国产精品香港三级国产av| 四虎永久免费地址入口| 国产精品星空无限传媒| 野花社区免费观看在线www| 国产良妇出轨视频在线观看| 狠狠色噜噜狠狠狠7777奇米| 成人片黄网站色大片免费| 伊人久久精品在热线热| 欧洲日本一线二线三线区本庄铃 | 久久婷婷五月综合国产尤物app| 熟妇人妻中文字幕无码老熟妇| 香蕉久久福利院| 秋霞鲁丝片av无码| 免费网站看v片在线18禁无码| 男人的天堂2018无码| 天天av天天翘天天综合网色鬼| 国产成人无码a区在线观看导航| 成年无码动漫av片在线观看羞羞| 免费无码观看的av在线播放| 亚洲图片综合图区20p| 无码熟妇αⅴ人妻又粗又大| 国产精品国产三级在线专区| 国产av久久人人澡人人爱| 亚洲精品综合欧美一区二区三区| 亚洲精品乱码久久久久久中文字幕| 午夜男女爽爽影院免费视频下载| 伊人久久大香线蕉亚洲| 国产精品女人呻吟在线观看| 国产无遮挡a片无码免费软件| av在线播放日韩亚洲欧| 免费国产黄网站在线观看视频| 久久天堂av综合合色蜜桃网|