在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PSMC4 Antibody, HRP conjugated

PSMC4 Antibody, HRP conjugated

  • 中文名稱：
    PSMC4兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA018894LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PSMC4 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PSMC4
  • 別名：
    26S protease regulatory subunit 6B antibody; 26S proteasome AAA ATPase subunit RPT3 antibody; 26S proteasome AAA-ATPase subunit RPT3 antibody; MB67 interacting protein antibody; MB67-interacting protein antibody; MIP224 antibody; Protease 26S subunit 6 antibody; Proteasome (prosome macropain) 26S subunit ATPase 4 antibody; Proteasome 19S S6 antibody; Proteasome 26S subunit ATPase 4 antibody; Proteasome 26S subunit; ATPase; 4 antibody; PRS6B_HUMAN antibody; PSMC4 antibody; RPT3 antibody; S6 antibody; Tat binding protein 7 antibody; TAT-binding protein 7 antibody; TBP 7 antibody; TBP-7 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human 26S proteasome regulatory subunit 6B protein (112-181AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
  • 基因功能參考文獻：
    1. This study demonstrated that particular distribution for HSC70 and PSMC4 in the cytoplasm and accumulation within Lewy body in the dopaminergic neurons of the substantia nigra in Parkinson patients. PMID: 29218503
    2. Structural mechanism for nucleotide-driven remodeling of RPT3 and its homologs in the activated human 26S proteasome has been reported. PMID: 29636472
    3. Site-specific Rpt3 phosphorylation by DYRK2 controls cell proliferation and tumorigenesis in breast neoplasms. PMID: 26655835
    4. Saquinavir-NO inhibits activation of S6 protein in androgen-dependent prostate cancer cells. PMID: 22370480
    5. The proposed TRAP1 network has an impact in vivo, as it is conserved in human colorectal cancers, is controlled by ER-localized TRAP1 interacting with TBP7 and provides a novel model of the ER-mitochondria crosstalk. PMID: 21979464
    6. C terminus of Rpt3, an ATPase subunit of PA700 (19 S) regulatory complex, is essential for 26 S proteasome assembly but not for activation PMID: 20937828
    7. interacts with gankyrin through C-terminal 78 amino acids PMID: 11779854
    8. a novel specific interaction of synphilin-1 with the regulatory proteasomal protein S6 ATPase (tbp7) in aggresome-like intracytoplasmic inclusions PMID: 17327361
    9. An insertion/deletion variant in intron 5 of the S6 ATPase gene was more frequent in German Parkinson's disease patients compared to controls PMID: 18446261

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    AAA ATPase family
  • 數據庫鏈接：

    HGNC: 9551

    OMIM: 602707

    KEGG: hsa:5704

    STRING: 9606.ENSP00000157812

    UniGene: Hs.211594



主站蜘蛛池模板： 色婷婷狠狠久久综合五月| 牲交欧美兽交欧美| 日韩一欧美内射在线观看| 狠狠色狠狠色综合久久| 免费无人区男男码卡二卡| 久久久亚洲精品av无码| 毛片无码免费无码播放| 国产乱子轮xxx农村| 偷偷要色偷偷中文无码| 777米奇影院狠狠色| 99久久精品费精品国产一区二区| av色综合久久天堂av色综合在 | 国产无套中出学生姝| 无码av天堂一区二区三区| 日韩卡1卡2 卡三卡免费| 欧美阿v高清资源在线| 黑人巨茎大战白人美女| 日本久久久久久久做爰片日本| 97性无码区免费| 亚洲国产成人精品无码区在线| 欧美精品videosex性欧美| 秋霞午夜久久午夜精品| 少妇高潮惨叫久久久久电影| 九九热爱视频精品视频| 亚洲熟妇无码乱子av电影| 久久久国产99久久国产久麻豆| 免费看成人毛片无码视频| 自拍性旺盛老熟女| 猫咪www免费人成网站无码| 私人家庭影院5777| 日日碰狠狠躁久久躁| 边啃奶头边躁狠狠躁| 亚洲欧洲自拍拍偷精品网 | 日本大香伊一区二区三区| 狠狠热精品免费视频| 成 人色 网 站 欧美大片在线观看| 亚洲精品高清国产一久久| 国产精品激情av久久久青桔| 久久婷婷五月综合97色直播| 国产一区二区亚洲精品| 嫩草av久久伊人妇女超级a|