在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PSMA3 Antibody, FITC conjugated

PSMA3 Antibody, FITC conjugated

  • 中文名稱：
    PSMA3兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA018867LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PSMA3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PSMA3
  • 別名：
    HC8 antibody; Macropain subunit C8 antibody; MGC12306 antibody; MGC32631 antibody; Multicatalytic endopeptidase complex subunit C8 antibody; Proteasome (prosome macropain) subunit alpha type 3 antibody; Proteasome alpha 3 subunit antibody; Proteasome component C8 antibody; Proteasome subunit alpha type 3 antibody; Proteasome subunit alpha type-3 antibody; Proteasome subunit C8 antibody; PSA3_HUMAN antibody; PSC8 antibody; psmA3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Proteasome subunit alpha type-3 protein (218-248AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Binds to the C-terminus of CDKN1A and thereby mediates its degradation. Negatively regulates the membrane trafficking of the cell-surface thromboxane A2 receptor (TBXA2R) isoform 2.
  • 基因功能參考文獻：
    1. High PSMA3 expression is associated with cholangiocarcinoma. PMID: 28560424
    2. Our results provide evidence on new T1DM-susceptible loci in the PSMA3, PSMA6 and PSMC6 proteasome genes and give a new insight into the T1DM pathogenesis PMID: 26661414
    3. Evidence of a sex-specific association of PSMA3 genetic variants with subtypes of juvenile idiopathic arthritis. PMID: 24875235
    4. Protein interaction between Ambn and Psma3 can facilitate redistribution of ameloblastin domains within forming enamel. PMID: 26070558
    5. A combination of two-dimensional gel electrophoresis (2D-GE) and tandem mass-spectrometry revealed a large number of PSMA3-bound proteins that are involved in various aspects of mRNA metabolism, including splicing. PMID: 22079093
    6. Serum 20S proteasome concentration and percentage of lymphocytic apoptosis predicted survival and patient prognosis in critically ill patients. PMID: 21108816
    7. Plasminogen activator inhibitor type 1 interacts with alpha3 subunit of proteasome and modulates its activity. PMID: 21135093
    8. Aurora-B might undergo degradation by binding to HC8 in a proteasome-dependent manner during mitosis PMID: 14674694
    9. EBNA3C binds to human the C8/alpha7 subunit of the 20S proteasome; degraded by purified 20S proteasomes in vitro but, found to be very stable and apparently turned over at a very low rate in B cells infected latently with EBV PMID: 15831937
    10. The authors propose that the full-length HCV F protein as well as the F protein initiating from codon 26 is degraded by an ubiquitin-independent pathway that is mediated by the proteasome subunit alpha3. PMID: 18971267

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Peptidase T1A family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 9532

    OMIM: 176843

    KEGG: hsa:5684

    STRING: 9606.ENSP00000216455

    UniGene: Hs.558799



主站蜘蛛池模板： 欧美金妇欧美乱妇xxxx| 天天av天天翘天天综合网| 日韩成人无码一区二区三区| 又色又爽又高潮免费视频国产 | 国产精品久久久久影院嫩草| 久久tv中文字幕首页| 天码欧美日本一道免费| 成人18禁深夜福利网站app免费| 朝鲜美女黑毛bbw| 亚洲欧美日韩国产综合v| 免费人成激情视频在线观看| 欧美人与性动交g欧美精器| 夜鲁鲁鲁夜夜综合视频欧美| 在线观看片免费人成视频播放| 国产美熟女乱又伦av果冻传媒| 亚洲男人第一av网站| 可以看三级的网站| 国产成人精品日本亚洲一区| 人人妻人人爽人人添夜夜欢视频 | 久久精品国产亚洲a片高清不卡| 香蕉97超级碰碰碰免费公开| 久久久国产精品人人片| 最新亚洲春色av无码专区| 女人爽到喷水的视频大全| 草草网站影院白丝内射| 337p日本欧洲亚洲大胆裸体艺术| 国产无套内射又大又猛又粗又爽| 亚洲中文字幕无码一去台湾| 成人做爰视频www| 波多野结衣美乳人妻hd电影欧美| 大肉大捧一进一出视频出来呀| 欧美老肥妇多毛xxxxx| 亚洲乱亚洲乱妇50p| 后入内射欧美99二区视频| 国产成人av无码永久免费一线天| 亚洲国产精品久久久久久久| 东京热一区二区三区无码视频 | 满春阁精品a∨在线观看| 国产免费踩踏调教视频| 久久精品中文字幕无码 | 国内精品久久久久久久影视麻豆|