在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PPP1R8 Antibody

PPP1R8 Antibody

  • 中文名稱：
    PPP1R8兔多克隆抗體
  • 貨號：
    CSB-PA030178
  • 規(guī)格：
    ￥1090
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    PPP1R8
  • 別名：
    Activator of RNA decay antibody; ARD 1 antibody; ARD-1 antibody; ARD1 antibody; Homolog of E.coli RNase E antibody; NIPP 1 antibody; NIPP-1 antibody; NIPP1 antibody; Nuclear inhibitor of protein phosphatase 1 antibody; nuclear inhibitor of protein phosphatase-1 alpha antibody; Nuclear subunit of PP1 antibody; PP1R8_HUMAN antibody; PPP1R8 antibody; PRO2047 antibody; Protein phosphatase 1 regulatory inhibitor subunit 8 antibody; Protein phosphatase 1 regulatory subunit 8 antibody; RNase E antibody; RNase E, E. coli, homolog of antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human NIPP1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation.; Isoform Gamma is a site-specific single-strand endoribonuclease that cleaves single strand RNA 3' to purines and pyrimidines in A+U-rich regions. It generates 5'-phosphate termini at the site of cleavage. This isoform does not inhibit PP-1. May be implicated in mRNA splicing.
  • 基因功能參考文獻：
    1. NIPP1 could be activated by hypoxia and contributed to hypoxia-induced invasive and metastatic potential in hepatocellular carcinoma. PMID: 27644248
    2. Data suggest overexpression of NIPP1 in HeLa cells causes induction of genes of mesenchymal lineage with reduction in cell proliferation; thus, key dephosphorylation events may be involved in epithelial-mesenchymal transition or transdifferentiation. PMID: 25907536
    3. The protein phosphatase-1 regulator NIPP1 is also a splicing factor involved in a late step of spliceosome assembly PMID: 11909864
    4. NIPP1 has a role in the nuclear targeting and/or retention of PP1 PMID: 15501817
    5. Required for the global trimethylation of histone3 at lysine27 and is implicated in gene silencing by enhancer of zeste homolog (EZH)2. PMID: 17724462
    6. NIPP1 is present in a complex with EED and EZH2 in vivo and has distinct binding sites for these proteins. PMID: 17804093
    7. NMR structure of the NIPP1 FHA domain. PMID: 18253837
    8. NIPP1 works as a molecular sensor for PP1 to recognize phosphorylated Sap155. PMID: 18842582

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Nucleus speckle. Note=Primarily, but not exclusively, nuclear.; [Isoform Gamma]: Cytoplasm. Note=Found mainly in the cytoplasm.
  • 組織特異性：
    Ubiquitously expressed, with highest levels in heart and skeletal muscle, followed by brain, placenta, lung, liver and pancreas. Less abundant in kidney. The concentration and ratio between isoforms is cell-type dependent. Isoform Alpha (>90%) and isoform
  • 數(shù)據(jù)庫鏈接：

    HGNC: 9296

    OMIM: 602636

    KEGG: hsa:5511

    STRING: 9606.ENSP00000311677

    UniGene: Hs.533474



主站蜘蛛池模板： 自拍偷在线精品自拍偷99| 黄网在线观看免费网站| 日本肉体xxxx裸交| 四虎永久免费地址入口| 高清国产亚洲精品自在久久| 国产在线午夜不卡精品影院| 日本嫩交12一16xxx视频| 国产成人a视频高清在线观看| 欧美午夜特黄aaaaaa片| 日韩国产高清一区二区| 久久www成人片免费看| www成人国产高清内射| 国产一区二区不卡老阿姨| 国产自愉自愉免费精品七区| 国产成年码av片在线观看| 久久精品视频在线看| 女人下边被添全过视频的网址| 无遮挡又爽又刺激的视频| 久99视频精品免费观看福利| 嫩草国产露脸精品国产软件| 国产美女精品一区二区三区| 欲色影视天天一区二区三区色香欲| 午夜免费啪视频在线观看区 | 国产av一区最新精品| 国产毛片精品av一区二区| 亚洲精品一区二区中文字幕| 日本精品高清一区二区| 亚洲日韩av一区二区三区四区 | 日本人又黄又爽又色的视频| 日本二区三区欧美亚洲国产| 明星性猛交ⅹxxx乱大交| 国产成人免费97在线| 最新国产精品久久精品| 亚洲丰满熟女一区二区v| 国产嫖妓风韵犹存对白| 国产av久久久久精东av| 亚洲熟妇丰满大屁股熟妇| 狠狠狠狼鲁亚洲综合网| 男人的天堂av社区在线| 久9热视频这里只精品18| 国产看真人毛片爱做a片|