在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PPP1R8 Antibody

PPP1R8 Antibody

  • 中文名稱：
    PPP1R8兔多克隆抗體
  • 貨號：
    CSB-PA018555GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    PPP1R8
  • 別名：
    Activator of RNA decay antibody; ARD 1 antibody; ARD-1 antibody; ARD1 antibody; Homolog of E.coli RNase E antibody; NIPP 1 antibody; NIPP-1 antibody; NIPP1 antibody; Nuclear inhibitor of protein phosphatase 1 antibody; nuclear inhibitor of protein phosphatase-1 alpha antibody; Nuclear subunit of PP1 antibody; PP1R8_HUMAN antibody; PPP1R8 antibody; PRO2047 antibody; Protein phosphatase 1 regulatory inhibitor subunit 8 antibody; Protein phosphatase 1 regulatory subunit 8 antibody; RNase E antibody; RNase E, E. coli, homolog of antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human PPP1R8
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation.; Isoform Gamma is a site-specific single-strand endoribonuclease that cleaves single strand RNA 3' to purines and pyrimidines in A+U-rich regions. It generates 5'-phosphate termini at the site of cleavage. This isoform does not inhibit PP-1. May be implicated in mRNA splicing.
  • 基因功能參考文獻：
    1. NIPP1 could be activated by hypoxia and contributed to hypoxia-induced invasive and metastatic potential in hepatocellular carcinoma. PMID: 27644248
    2. Data suggest overexpression of NIPP1 in HeLa cells causes induction of genes of mesenchymal lineage with reduction in cell proliferation; thus, key dephosphorylation events may be involved in epithelial-mesenchymal transition or transdifferentiation. PMID: 25907536
    3. The protein phosphatase-1 regulator NIPP1 is also a splicing factor involved in a late step of spliceosome assembly PMID: 11909864
    4. NIPP1 has a role in the nuclear targeting and/or retention of PP1 PMID: 15501817
    5. Required for the global trimethylation of histone3 at lysine27 and is implicated in gene silencing by enhancer of zeste homolog (EZH)2. PMID: 17724462
    6. NIPP1 is present in a complex with EED and EZH2 in vivo and has distinct binding sites for these proteins. PMID: 17804093
    7. NMR structure of the NIPP1 FHA domain. PMID: 18253837
    8. NIPP1 works as a molecular sensor for PP1 to recognize phosphorylated Sap155. PMID: 18842582

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Nucleus speckle. Note=Primarily, but not exclusively, nuclear.; [Isoform Gamma]: Cytoplasm. Note=Found mainly in the cytoplasm.
  • 組織特異性：
    Ubiquitously expressed, with highest levels in heart and skeletal muscle, followed by brain, placenta, lung, liver and pancreas. Less abundant in kidney. The concentration and ratio between isoforms is cell-type dependent. Isoform Alpha (>90%) and isoform
  • 數據庫鏈接：

    HGNC: 9296

    OMIM: 602636

    KEGG: hsa:5511

    STRING: 9606.ENSP00000311677

    UniGene: Hs.533474



主站蜘蛛池模板： ā片在线观看免费观看| 熟妇丰满多毛的大隂户| 亚洲色播爱爱爱爱爱爱爱| 亚洲欧美日韩国产综合v| 又色又污又爽又黄的网站| 99热国产这里只有精品9| 女人夜夜春高潮爽a∨片传媒| 国产区精品一区二区不卡中文| 又色又爽又黄又无遮挡的网站| 无码av免费网站| 亚洲aⅴ天堂av天堂无码麻豆| 曰韩少妇内射免费播放| 亚洲精品一区二区丝袜图片| 成年女人看片永久免费视频 | 国产a在亚洲线播放| 亚洲欧美日本韩国| 亚洲 欧美 另类 制服 日韩| 亚洲v欧美v日韩v国产v| 国产精品久久久一区二区三区| 人妻 色综合网站| 亚洲中文字幕无码av永久| 草草影院精品一区二区三区| 成人免费乱码大片a毛片| 妺妺窝人体色www聚色窝| 9l国产精品久久久久尤物| 亚洲综合av色婷婷| 日韩av无码一区二区三区不卡毛片| 国产精品久久久久久不卡盗摄| 久久久精品国产免大香伊| 肉大榛一进一出免费视频| 国产精品久久无码不卡黑寡妇 | 国产成人久久精品二区三区| 三级视频兔费看| 国产情侣草莓视频在线| 真人啪啪高潮喷水呻吟无遮挡 | 欧洲亚洲色一区二区色99| 久久精品第一国产久精国产宅男66| 无码av片在线观看免费| 999久久久国产精品| 国产97色在线 | 免费| 99久久久无码国产精品动漫|