在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PPP1R3A Antibody

  • 中文名稱:
    PPP1R3A兔多克隆抗體
  • 貨號:
    CSB-PA030172
  • 規(guī)格:
    ¥1090
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    Glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle antibody; Glycogen associated regulatory subunit of protein phosphatase 1 antibody; GM antibody; PP1G antibody; PPP1R3 antibody; PPP1R3A antibody; PPR3A_HUMAN antibody; Protein phosphatase 1 glycogen-associated regulatory subunit antibody; Protein phosphatase 1 glycogen-targeting subunit, muscle antibody; Protein phosphatase 1 regulatory subunit 3A antibody; Protein phosphatase 1 regulatory subunit GM antibody; protein phosphatase 1, regulatory (inhibitor) subunit 3A antibody; Protein phosphatase 1, regulatory subunit 3 antibody; Protein phosphatase type-1 glycogen targeting subunit antibody; RG1 antibody; Serine /threonine specific protein phosphatase antibody; Type 1 protein phosphatase skeletal muscle glycogen targeting subunit antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human PPP1R3A.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase.
  • 基因功能參考文獻:
    1. Variant in PPP1R3A is associated with type 2 diabetes. PMID: 29948331
    2. In the univariate analyses, TP53, PPP1R3A, and KMT2B were significantly more frequently mutated in interval cancers than in screen-detected cancers. PMID: 27587435
    3. results demonstrate that hScrib acts as a scaffold to integrate the control of the PP1gamma and ERK signaling pathways and explains how disruption of hScrib localisation can contribute towards the development of human malignancy PMID: 23359326
    4. A joint effect between the Asp905 and BMI increases the risk of type 2 diabetes, and Asp905Tyr and ARE polymorphism of PPP1R3 gene are not the major diabetogenic gene variants in Chinese population. PMID: 11793847
    5. G(M) promotes glycogen storage and inversely regulates glycogen synthase and glycogen phosphorylase activities, while, specifically, synthase phosphatase activity of G(M)-PP1 is inhibited by glycogen. PMID: 12941760
    6. Among the largest cohort of nondiabetic subjects (Caucasian, n = 112), the presence of the deletion allele (ARE-2) was associated with insulin resistance and hyperandrogenemia. PMID: 15181086
    7. Inactivation of PPP1R3 gene is associated with tumor progression and metastasis of colorectal cancers PMID: 15870946
    8. PPP1R3A C1984DeltaAG (stop codon 668) isthe 1st prevalent mutation that directly impairs glycogen synthesis & decreases glycogen levels in human skeletal muscle. It is present in approximately 1 in 70 UK whites. PMID: 18232732

    顯示更多

    收起更多

  • 相關疾病:
    Diabetes mellitus, non-insulin-dependent (NIDDM)
  • 亞細胞定位:
    Membrane; Single-pass membrane protein.
  • 組織特異性:
    Skeletal muscle and heart.
  • 數據庫鏈接:

    HGNC: 9291

    OMIM: 125853

    KEGG: hsa:5506

    STRING: 9606.ENSP00000284601

    UniGene: Hs.458309



主站蜘蛛池模板: 囯产精品一区二区三区线| 久久久久77777人人人人人| 国产亚洲香蕉线播放αv38| 国产98在线 | 免费| 国产亚洲精久久久久久无码| 中国女人内谢69xxxxxa片| 成人无码视频在线观看大全| 亚洲另类欧美在线电影| 久久精品视频在线看| 国内精品自在自线| 久久久综合香蕉尹人综合网 | 国产成+人欧美+综合在线观看| 爱久久av一区二区三区| 亚洲国产成人久久综合一区| 中文乱码字幕视频观看网站免费| 成人精品免费视频在线观看| 2020无码天天喷水天天爽| 鲁丝一区二区三区免费| 狠狠爱亚洲五月婷婷av| 无码福利在线观看1000集| 国产3p露脸普通话对白| 漂亮人妻去按摩被按中出| 国内久久婷婷五月综合色| 产后漂亮奶水人妻无码| 日本阿v网站在线观看中文| 成人免费777777| 亚洲视频无码高清在线| 欧美日韩国产综合新一区| 国产大屁股喷水视频在线观看| 日韩国产高清一区二区| 2021久久超碰国产精品最新| 无码丰满少妇2在线观看| 国产97色在线 | 国产| 欧美人与动人物牲交免费观看 | 看国产黄大片在线观看| 久久久久国产精品| 亚洲综合一区国产精品| 少妇高潮太爽了在线视频| 美女露全乳无遮掩视频| 国产成人精品自在线导航| 18禁成人黄网站免费观看久久 |