在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PPM1F Antibody

PPM1F Antibody

  • 中文名稱：
    PPM1F兔多克隆抗體
  • 貨號：
    CSB-PA288701
  • 規格：
    ￥1100
  • 圖片：
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human fetal liver tissue, K562 cells, Primary antibody: CSB-PA288701(PPM1F Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    PPM1F
  • 別名：
    Ca(2+)/calmodulin-dependent protein kinase phosphatase antibody; CaM-kinase phosphatase antibody; CAMKP antibody; CaMKPase antibody; FEM 2 antibody; hFEM-2 antibody; KIAA0015 antibody; Partner of PIX 2 antibody; POPX2 antibody; PP2C phosphatase antibody; Ppm1f antibody; PPM1F_HUMAN antibody; Protein fem-2 homolog antibody; Protein phosphatase 1F (PP2C domain containing) antibody; Protein phosphatase 1F antibody; Protein phosphatase Mg2+/Mn2+ dependent 1F antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human PPM1F
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Dephosphorylates and concomitantly deactivates CaM-kinase II activated upon autophosphorylation, and CaM-kinases IV and I activated upon phosphorylation by CaM-kinase kinase. Promotes apoptosis.
  • 基因功能參考文獻：
    1. PPM1F overexpression suppressed cell proliferation and invasion and counteracted the tumour-promoting role of miR-590, but PPM1F knockdown reversed these effects. PMID: 29473240
    2. POPX2 is a negative regulator of TAK1 signaling pathway and modulates apoptosis through the regulation of TAK1 activity. PMID: 28906490
    3. PPM1F could work downstream of alpha9-nAchR to promote nicotine-induced carcinogenic signals. Thus, PPM1F expression could be used for prognostic diagnosis, or inhibited as a potential strategy for cancer prevention and therapy. PMID: 27769050
    4. This study, combined with our previous findings, suggests that a single ubiquitously expressed phosphatase POPX2 influences cancer metastasis via modulating multiple biological processes including MAPK signaling and exosome cytokine secretion. PMID: 27976581
    5. Overexpression of PPM1F is associated with metastasis of hepatocellular carcinoma. PMID: 26498692
    6. POPX2 affects trafficking by determining the phosphorylation status of KIF3A at serine 690. PMID: 24338362
    7. POPX2 might regulate cell motility through its regulation of the MAPK1/3, leading to changes in the cytoskeleton and cell motility. PMID: 23621870
    8. hCaMKP activity is reversibly regulated by oxidation/reduction at Cys-359 PMID: 22743349
    9. FHOD1 and PPM1F (direct regulators of the actin cytoskeleton) were identified as novel targets of miR-200c. Expression levels of FHOD1 and PPM1F were inversely correlated with miR-200c level in breast cancer cell lines and breast cancer patient samples. PMID: 22144583
    10. Data identify a biochemical pathway through which POPX2 exerts its apparent cellular function: the regulation of activity of glycogen synthase kinase-3, which in turn modulates extracellular signal-regulated kinase and cell motility. PMID: 21656682
    11. The POPX2 phosphatase regulates cancer cell motility and invasiveness. PMID: 20016286
    12. The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family. (POPX1; POPX2) PMID: 11864573
    13. PPM1F plays a key role in the regulation of CaMKII intracellularly PMID: 15140879

    顯示更多

    收起更多

  • 蛋白家族：
    PP2C family
  • 數據庫鏈接：

    HGNC: 19388

    KEGG: hsa:9647

    STRING: 9606.ENSP00000263212

    UniGene: Hs.112728



主站蜘蛛池模板： 18黄暴禁片在线观看| 女人被狂爆到高潮免费视频| 久久久久国产精品人妻aⅴ院| 国精品无码av人妻受辱系| 亚洲伊人色欲综合网无码中文| 337p日本欧洲亚洲大胆在线| 久久久久无码国产精品一区| 欧美丰满大乳大屁股流白浆| 五月丁香综合缴情六月小说| 免费观看男女性高视频| 300部国产真实乱| 亚洲国产精品久久久久爰色欲| 色欲天天婬色婬香综合网完整 | 无码人妻一区二区三区一| 中文字幕一二三区波多野结衣| 青青草国产免费国产是公开| 女人喷潮完整视频| 色综合99久久久无码国产精品| 女人和拘做受全程看视频| 国产午夜鲁丝片av无码免费| 亚洲乱码一区二区三区在线观看 | 色欲av亚洲一区无码少妇 | 成人h动漫精品一区二区| 中文字幕亚洲综合久久综合| 国产制服丝袜欧美在线观看| 国产香蕉尹人视频在线| 欧美xxxx黑人又粗又长精品 | 国产亚洲精品岁国产微拍精品 | 国产精品国产亚洲精品看不卡| 九色porny丨国产首页注册| 天堂最新版资源网| 亚洲精品少妇高清30p| 5858s亚洲色大成网站www| 老司机午夜免费精品视频| 精品成人免费国产片| 婷婷五月综合色中文字幕| 久久精品国产亚洲7777| 国产精品无码av天天爽| 麻豆国产原创视频在线播放 | 国产熟女出轨做受的叫床声| 无码av高潮喷水无码专区线|