在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PPM1F Antibody, HRP conjugated

  • 中文名稱:
    PPM1F兔多克隆抗體, HRP偶聯(lián)
  • 貨號:
    CSB-PA018493LB01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) PPM1F Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    PPM1F
  • 別名:
    Ca(2+)/calmodulin-dependent protein kinase phosphatase antibody; CaM-kinase phosphatase antibody; CAMKP antibody; CaMKPase antibody; FEM 2 antibody; hFEM-2 antibody; KIAA0015 antibody; Partner of PIX 2 antibody; POPX2 antibody; PP2C phosphatase antibody; Ppm1f antibody; PPM1F_HUMAN antibody; Protein fem-2 homolog antibody; Protein phosphatase 1F (PP2C domain containing) antibody; Protein phosphatase 1F antibody; Protein phosphatase Mg2+/Mn2+ dependent 1F antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Protein phosphatase 1F protein (1-76AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Dephosphorylates and concomitantly deactivates CaM-kinase II activated upon autophosphorylation, and CaM-kinases IV and I activated upon phosphorylation by CaM-kinase kinase. Promotes apoptosis.
  • 基因功能參考文獻:
    1. PPM1F overexpression suppressed cell proliferation and invasion and counteracted the tumour-promoting role of miR-590, but PPM1F knockdown reversed these effects. PMID: 29473240
    2. POPX2 is a negative regulator of TAK1 signaling pathway and modulates apoptosis through the regulation of TAK1 activity. PMID: 28906490
    3. PPM1F could work downstream of alpha9-nAchR to promote nicotine-induced carcinogenic signals. Thus, PPM1F expression could be used for prognostic diagnosis, or inhibited as a potential strategy for cancer prevention and therapy. PMID: 27769050
    4. This study, combined with our previous findings, suggests that a single ubiquitously expressed phosphatase POPX2 influences cancer metastasis via modulating multiple biological processes including MAPK signaling and exosome cytokine secretion. PMID: 27976581
    5. Overexpression of PPM1F is associated with metastasis of hepatocellular carcinoma. PMID: 26498692
    6. POPX2 affects trafficking by determining the phosphorylation status of KIF3A at serine 690. PMID: 24338362
    7. POPX2 might regulate cell motility through its regulation of the MAPK1/3, leading to changes in the cytoskeleton and cell motility. PMID: 23621870
    8. hCaMKP activity is reversibly regulated by oxidation/reduction at Cys-359 PMID: 22743349
    9. FHOD1 and PPM1F (direct regulators of the actin cytoskeleton) were identified as novel targets of miR-200c. Expression levels of FHOD1 and PPM1F were inversely correlated with miR-200c level in breast cancer cell lines and breast cancer patient samples. PMID: 22144583
    10. Data identify a biochemical pathway through which POPX2 exerts its apparent cellular function: the regulation of activity of glycogen synthase kinase-3, which in turn modulates extracellular signal-regulated kinase and cell motility. PMID: 21656682
    11. The POPX2 phosphatase regulates cancer cell motility and invasiveness. PMID: 20016286
    12. The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family. (POPX1; POPX2) PMID: 11864573
    13. PPM1F plays a key role in the regulation of CaMKII intracellularly PMID: 15140879

    顯示更多

    收起更多

  • 蛋白家族:
    PP2C family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 19388

    KEGG: hsa:9647

    STRING: 9606.ENSP00000263212

    UniGene: Hs.112728



主站蜘蛛池模板: 中文字幕 欧美精品 第1页| 色欲av伊人久久大香线蕉影院| 国产中年熟女高潮大集合| av高清无码 在线播放| 亚洲色爱免费观看视频| 中文字幕人乱码中文| 扒开双腿疯狂进出爽爽爽| 东京热人妻无码一区二区av| 一本一本久久a久久综合精品 | 6080亚洲人久久精品| 国产精品国产三级国产专区53| 老子午夜精品无码不卡| 久久精品国产亚洲夜色av网站 | 久久久青草青草免费看| 最新 国产 精品 精品 视频| 国产啪精品视频网站| 在线 | 一区二区三区| 日本久久综合久久综合| 又色又爽又黄还免费毛片96下载| 日本免费一区二区三区视频观看| 亚洲2022国产成人精品无码区| 一本大道久久东京热av| 奇米影视7777狠狠狠狠影视 | 国产最大成人亚洲精品| 538在线精品视频| 中文字幕热久久久久久久| 日韩精品一区二区大桥未久 | 波多野结av在线无码中文| 日日鲁鲁鲁夜夜爽爽狠狠视频97 | 午夜人妻久久久久久久久| 精品乱码久久久久久中文字幕| 国模无码一区二区三区不卡| 日韩精品无码熟人妻视频| 久久久久成人精品免费播放动漫 | 在教室伦流澡到高潮hgl动漫| 鲁鲁网亚洲站内射污| 欧美黑人又大又粗xxxxx| 亚洲va久久久噜噜噜久久男同| 日本亚洲欧美综合在线| 久久aaaa片一区二区| 老子午夜理论影院理论|