在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PPAP2A Antibody

PPAP2A Antibody

  • 中文名稱：
    PPAP2A兔多克隆抗體
  • 貨號：
    CSB-PA918814
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA918814(PPAP2A Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA918814(PPAP2A Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 30 μg, Lane: Human liver cancer tissue, Primary antibody: CSB-PA918814(PPAP2A Antibody) at dilution 1/650, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    PLPP1; LPP1; PPAP2A; Phospholipid phosphatase 1; Lipid phosphate phosphohydrolase 1; PAP2-alpha; Phosphatidate phosphohydrolase type 2a; Phosphatidic acid phosphatase 2a; PAP-2a; PAP2a
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide of Human PPAP2A
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Magnesium-independent phospholipid phosphatase of the plasma membrane that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate esters including phosphatidate/PA, lysophosphatidate/LPA, diacylglycerol pyrophosphate/DGPP, sphingosine 1-phosphate/S1P and ceramide 1-phosphate/C1P. Also acts on N-oleoyl ethanolamine phosphate/N-(9Z-octadecenoyl)-ethanolamine phosphate, a potential physiological compound. Through its extracellular phosphatase activity allows both the hydrolysis and the cellular uptake of these bioactive lipid mediators from the milieu, regulating signal transduction in different cellular processes. It is for instance essential for the extracellular hydrolysis of S1P and subsequent conversion into intracellular S1P. Involved in the regulation of inflammation, platelets activation, cell proliferation and migration among other processes. May also have an intracellular activity to regulate phospholipid-mediated signaling pathways.
  • 基因功能參考文獻：
    1. the first of the two transmembrane regions in human SAC1 (TM1) functions in Golgi localization PMID: 23936490
    2. Phosphorylation of lipin 1 and charge on the phosphatidic acid head group control its phosphatidic acid phosphatase activity and membrane association PMID: 23426360
    3. this enzyme regulates interleukin-4-mediated STAT6 signaling. PMID: 12426308
    4. This protein and phosphoprotein SET regulate androgen production by P450c17. PMID: 12444089
    5. lipid phosphate phosphatase-1 has a role in regulating accumulation of lysophosphatidic acid in ovarian cancer PMID: 14506139
    6. Lipopolysaccharide-induced up-regulation of cyclooxygenase-2 depends on the activity of the Mg(+2)-dependent phosphatidic acid phosphohydrolase 1 (PAP-1) PMID: 16950767
    7. LPP1 and LPP3 are distributed in distinct lipid rafts that may provide unique microenvironments defining their non-redundant physiological functions. PMID: 17005594
    8. These results suggest that the expression of PAP2a is directly regulated by p73. PMID: 17169329
    9. These results suggest that LPP1a is important for the determination of plasma FTY720-P levels. PMID: 18755152

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein. Membrane, caveola; Multi-pass membrane protein.
  • 蛋白家族：
    PA-phosphatase related phosphoesterase family
  • 組織特異性：
    Widely expressed with highest expression found in prostate. Found to be down-regulated in colon adenocarcinomas.; [Isoform 1]: Predominant in kidney, lung, placenta and liver.; [Isoform 2]: Predominant in heart and pancreas.
  • 數據庫鏈接：

    HGNC: 9228

    OMIM: 607124

    KEGG: hsa:8611

    UniGene: Hs.696231



主站蜘蛛池模板： 东京热人妻丝袜av无码| 日韩人妻无码精品一专区| 国产成人无码免费视频97| 免费无码成人av片在线在线播放| 7777奇米四色成人眼影| 免费国精产品自偷自偷免费看| 精品成人免费一区二区不卡| 亚洲中文有码字幕日本| 国产重口老太和小伙| 中日av乱码一区二区三区乱码| 国产精品亚洲精品日韩已满| 国产成人18黄网站在线观看| 精品一二三区久久aaa片| 又粗又大又硬又长又爽| 三级做a全过程在线观看| 亚洲精品人成网线在播放va | 精品无码国产自产拍在线观看蜜| 免费永久看黄神器无码软件| 久久天天躁狠狠躁夜夜爽| 欧美老妇交乱视频在线观看| 成人性生交大片免费看小说| 婷婷色香五月综合缴缴情| 久久精晶国产99久久6| 亚洲熟女乱色综合亚洲图片 | 久久男人av资源网站| 国产深夜男女无套内射| 国产乱码精品一品二品| 乱人伦无码中文视频在线| 玖玖资源站无码专区| 国产亚洲精品久久久久久久 | 翘臀后进少妇大白嫩屁股| 日本精品aⅴ一区二区三区| 内射国产内射夫妻免费频道| 国产高清japanese在线播放e| 午夜成人亚洲理论片在线观看 | 成熟老妇女视频| 18禁亚洲深夜福利入口| 欧美一区二区日韩国产| 97人妻天天摸天天爽天天| 牲交a欧美牲交aⅴ免费一| 玩弄少妇的肉体k8经典|