在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

POLG2 Antibody

  • 中文名稱:
    POLG2兔多克隆抗體
  • 貨號:
    CSB-PA006798
  • 規格:
    ¥1090
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    POLG2
  • 別名:
    DNA directed DNA polymerase gamma 2 antibody; DNA polymerase gamma accessory 55 kDa subunit antibody; DNA polymerase subunit gamma 2; mitochondrial antibody; DNA polymerase subunit gamma-2 antibody; DPOG2_HUMAN antibody; HP55 antibody; mitochondrial antibody; Mitochondrial DNA polymerase accessory subunit antibody; Mitochondrial DNA polymerase subunit gamma 2 antibody; Mitochondrial polymerase gamma 2 antibody; MtPolB antibody; OTTMUSP00000003758 antibody; p55 antibody; PEOA4 antibody; POLB antibody; PolG beta antibody; PolG-beta antibody; POLG2 antibody; POLGB antibody; Polymerase (DNA directed); gamma 2; accessory subunit antibody; Polymerase; gamma 2 antibody; RP23-247J12.3 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human DNA pol γ2.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Mitochondrial polymerase processivity subunit. It regulates the polymerase and exonuclease activities promoting processive DNA synthesis. Binds to ss-DNA.
  • 基因功能參考文獻:
    1. This is the first report of a patient with a homozygous mutation in POLG2 and with a clinical presentation of severe hepatic failure and mitochondrial depletion. PMID: 27592148
    2. Results show that polymorphisms at POLG2 and POLRMT increased risk of oral cancer and leukoplakia, respectively, probably modulating synthesis and activity of the enzymes. PMID: 26403317
    3. Mitochondrial DNA (mtDNA) content plays an important role in energy production and sustaining normal physiological function. PMID: 24524965
    4. The authors describe the molecular characterization of a potential dominant POLG2 mutation (p.R369G) in a patient with autosomal dominant progressive external ophthalmoplegia and multiple mtDNA deletions. PMID: 22155748
    5. Data show that rs17650301 in POLG2 is a good candidate marker for UBC invasiveness in Japanese males. PMID: 21734712
    6. The biochemical analysis helps explain the pathogenesis of POLG2 mutations in mitochondrial disease. PMID: 21555342
    7. human pol gammaB exhibits a catalytic subunit- and substrate DNA-dependent dimerization. PMID: 19858216
    8. PolB gamma can bind double-stranded DNA and may play a role in DNA replication or repair PMID: 12379656
    9. Study represents the first structure-function analysis of the thumb subdomain in pol gamma and examines the consequences of mitochondrial disease mutations in this region. PMID: 19478085
    10. Both increased and decreased expression of POLGbeta altered nucleoid structure and precipitated a marked decrease in 7S DNA molecules, which form short displacement-loops on mitochondrial DNA. PMID: 19625489

    顯示更多

    收起更多

  • 相關疾病:
    Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant, 4 (PEOA4)
  • 亞細胞定位:
    Mitochondrion.
  • 數據庫鏈接:

    HGNC: 9180

    OMIM: 604983

    KEGG: hsa:11232

    STRING: 9606.ENSP00000442563

    UniGene: Hs.437009



主站蜘蛛池模板: 国产av无码国产av毛片| 国产成人精品日本亚洲| 国产成人毛片无码视频软件| 国产漂亮白嫩美女在线观看| 新普新京亚洲欧美日韩国产| 国产精品自在拍首页视频8| 特级毛片在线大全免费播放| 亚洲无线码在线一区观看| 色欲色香天天天综合无码| 人妻精品久久无码区| 狠狠躁18三区二区一区ai明星| 中文av伊人av无码av狼人| 欧美日韩亚洲国产欧美电影 | 国产精品美女久久久网av| 欧美变态暴力牲交videos| 99在线 | 亚洲| 18禁超污无遮挡无码免费动态图| 大胆欧美熟妇xxbbwwbw高潮了| 特黄大片又粗又大又暴| 青青青国产免a在线观看| 国产卡一卡二卡三卡免费| 人妻少妇精品久久| 波多野结衣美乳人妻hd电影欧美| 玖玖资源站最稳定网址| 亚洲国产超清无码专区| 中文字幕资源网| 婷婷亚洲久悠悠色悠在线播放| 精品国产一区二区三区四区在线看| 久久www成人看片免费不卡| 久久精品亚洲中文无东京热| 国产精品沙发午睡系列| 西西人体大胆4444www| 日本久久夜夜一本婷婷| 国产成人av男人的天堂| 99久久国产宗和精品1上映| 国产sm鞭打折磨调教视频| 欧美日韩国产综合新一区| 丰满人妻熟妇乱又伦精品视 | 欧美亚洲日本高清不卡| 奇米影视777四色米奇影院 | 人人做人人爽人人爱|