在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

POLG2 Antibody

  • 中文名稱:
    POLG2兔多克隆抗體
  • 貨號:
    CSB-PA018314GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    POLG2
  • 別名:
    DNA directed DNA polymerase gamma 2 antibody; DNA polymerase gamma accessory 55 kDa subunit antibody; DNA polymerase subunit gamma 2; mitochondrial antibody; DNA polymerase subunit gamma-2 antibody; DPOG2_HUMAN antibody; HP55 antibody; mitochondrial antibody; Mitochondrial DNA polymerase accessory subunit antibody; Mitochondrial DNA polymerase subunit gamma 2 antibody; Mitochondrial polymerase gamma 2 antibody; MtPolB antibody; OTTMUSP00000003758 antibody; p55 antibody; PEOA4 antibody; POLB antibody; PolG beta antibody; PolG-beta antibody; POLG2 antibody; POLGB antibody; Polymerase (DNA directed); gamma 2; accessory subunit antibody; Polymerase; gamma 2 antibody; RP23-247J12.3 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human POLG2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Mitochondrial polymerase processivity subunit. It regulates the polymerase and exonuclease activities promoting processive DNA synthesis. Binds to ss-DNA.
  • 基因功能參考文獻(xiàn):
    1. This is the first report of a patient with a homozygous mutation in POLG2 and with a clinical presentation of severe hepatic failure and mitochondrial depletion. PMID: 27592148
    2. Results show that polymorphisms at POLG2 and POLRMT increased risk of oral cancer and leukoplakia, respectively, probably modulating synthesis and activity of the enzymes. PMID: 26403317
    3. Mitochondrial DNA (mtDNA) content plays an important role in energy production and sustaining normal physiological function. PMID: 24524965
    4. The authors describe the molecular characterization of a potential dominant POLG2 mutation (p.R369G) in a patient with autosomal dominant progressive external ophthalmoplegia and multiple mtDNA deletions. PMID: 22155748
    5. Data show that rs17650301 in POLG2 is a good candidate marker for UBC invasiveness in Japanese males. PMID: 21734712
    6. The biochemical analysis helps explain the pathogenesis of POLG2 mutations in mitochondrial disease. PMID: 21555342
    7. human pol gammaB exhibits a catalytic subunit- and substrate DNA-dependent dimerization. PMID: 19858216
    8. PolB gamma can bind double-stranded DNA and may play a role in DNA replication or repair PMID: 12379656
    9. Study represents the first structure-function analysis of the thumb subdomain in pol gamma and examines the consequences of mitochondrial disease mutations in this region. PMID: 19478085
    10. Both increased and decreased expression of POLGbeta altered nucleoid structure and precipitated a marked decrease in 7S DNA molecules, which form short displacement-loops on mitochondrial DNA. PMID: 19625489

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant, 4 (PEOA4)
  • 亞細(xì)胞定位:
    Mitochondrion.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 9180

    OMIM: 604983

    KEGG: hsa:11232

    STRING: 9606.ENSP00000442563

    UniGene: Hs.437009



主站蜘蛛池模板: 又粗又黑又大的吊av| 日本不卡不码高清视频| 久久久久亚洲精品成人网| 2021精品国夜夜天天拍拍| 妓院一钑片免看黄大片| 国产亚洲精品自在久久蜜tv| 国产真实露脸乱子伦原著| 亚洲精品久久久久中文字幕| 国产八十老太另类| 香蕉成人伊视频在线观看| 中文字幕无线码中文字幕免费| 国产高清露脸孕妇系列| 国产av无码专区国产乱码| 日韩少妇人妻vs中文字幕| 亚洲最大无码中文字幕| 伊人久久综合无码成人网| 日韩精品一区二区三区在线观看l| 亚洲18禁私人影院| 欧美性大战xxxxx久久久√| 久久久精品久久日韩一区综合| 鲁鲁鲁爽爽爽在线视频观看| 男女做爰猛烈叫床视频动态图| 日本两人免费观看的视频| 天天狠天天透天干天天怕∴| 久久久久久久波多野结衣高潮| 99久久久无码国产精品秋霞网| 亚洲 自拍 另类 欧美 综合| 精品国产乱码久久久久久婷婷| 亚洲男人最新版本天堂| 天堂а√在线中文在线最新版 | 四虎国产精品免费久久久| 国产xxxx做受性欧美88| 成 人 a v免费视频在线观看| 又嫩又硬又黄又爽的视频| 国产精品人妻一区夜夜爱| 在线播放十八禁视频无遮挡| 日韩亚洲国产高清免费视频| 亚洲 高清 成人 动漫| 国产老熟女网站| 亚洲精品久久久久久久久久久捆绑| 欧美视频专区一二在线观看|