在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PNPO Antibody, FITC conjugated

  • 中文名稱:
    PNPO兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA885740LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PNPO Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    PNPO
  • 別名:
    EC 1.4.3.5 antibody; FLJ10535 antibody; PDXPO antibody; PNPO antibody; PNPO_HUMAN antibody; Pyridoxal 5' phosphate synthase antibody; pyridoxamine 5' phosphate oxidase antibody; Pyridoxamine phosphate oxidase antibody; Pyridoxamine-phosphate oxidase antibody; pyridoxine 5' phosphate oxidase antibody; Pyridoxine-5'-phosphate oxidase antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Pyridoxine-5'-phosphate oxidase protein (114-207AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
  • 基因功能參考文獻:
    1. TGF-beta1-mediated PNPO expression was at least in part through the upregulation of miR-143-3p in epithelial ovarian cancer. PMID: 29238081
    2. data support a pathogenic role of the c.347G>A (p.Arg116Gln) mutation in PNPO deficiency; the later onset of symptoms and the milder epilepsy phenotype of these expand the disease phenotype PMID: 28818555
    3. Exome sequencing revealed that the patient was compound heterozygous for pathogenic mutations [c.546+1G>A (IVS5+1 G>A) and c.620delG (p.G207VfsX215)] in the PNPO gene. PMID: 26535729
    4. One sequence variant, R116Q, a single nucleotide polymorphism that has been reported in the general population, was found to have an effect on PNPO activity. PMID: 24645144
    5. Challenge to the paradigm of exclusive PLP responsiveness in patients with pyridoxal 5'-phosphate oxidase deficiency and underlines the importance of consecutive testing of pyridoxine and PLP in neonates with antiepileptic drug-resistant seizures. PMID: 24658933
    6. Generalized epilepsies implicates susceptibility genes: CHRM3 at 1q43, VRK2 at 2p16.1, ZEB2 at 2q22.3, SCN1A at 2q24.3 and PNPO at 17q21.32. PMID: 22949513
    7. provide evidence that a single arginine residue of the C terminus of pyridoxal 5'-phosphate synthase is responsible for coordinating co-operativity in this elaborate protein machinery PMID: 21283685
    8. Results describe a combined computer and biochemical approach to characterize human pyridoxine 5'-phosphate oxidase (PNPO). PMID: 15182361
    9. several mutations appear to cause epilepsy PMID: 15772097
    10. We examined 8 single nucleotide polymorphisms (SNPs) in PNPO and its 5'-flanking regions in 359 schizophrenia patients and 582 control subjects. PMID: 17851041
    11. Sequencing of the PNPO gene revealed a novel homozygous nonsense mutationt in exon 3 in the neonatal and infantile seizure. PMID: 18485777
    12. PNP oxidase R229W mutation identified in patients with neonatal epileptic encephalopathy sgnificantly affect the catalytic efficiency of the enzyme. PMID: 19759001

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Pyridoxine-5'-phosphate oxidase deficiency (PNPOD)
  • 蛋白家族:
    Pyridoxamine 5'-phosphate oxidase family
  • 數據庫鏈接:

    HGNC: 30260

    OMIM: 603287

    KEGG: hsa:55163

    STRING: 9606.ENSP00000225573

    UniGene: Hs.631742



主站蜘蛛池模板: 人妻系列无码专区av在线| 久久久久久av无码免费网站下载 | 最新日韩精品中文字幕| 国产乡下妇女做爰| 伊人久久精品在热线热| 亚洲人成网站18禁止大| 水蜜桃av导航| 精品高潮呻吟99av无码视频| 久章草国语自产拍在线观看| 少妇无码av无码一区| 国语对白嫖老妇胖老太| 少妇性荡欲午夜性开放视频剧场| 色情一区二区三区免费看| 在线涩涩免费观看国产精品| 国产精品aⅴ视频在线播放| 国产精品原创av片国产日韩| 成人午夜视频精品一区| 九九影院午夜理论片少妇| 国产成人精品999视频| 欧美日本韩国亚洲| 小嫩妇好紧好爽再快视频| 亚洲国产天堂久久久久久| 国产台湾无码av片在线观看| 裸身美女无遮挡永久免费视频| 动漫精品啪啪一区二区三区| 高清破外女出血av毛片| 欧美最猛性xxxxx大叫| 国产成人无码av一区二区| 亚洲第一av网站| 亚洲中文字幕aⅴ无码天堂| 67194熟妇人妻欧美日韩| 午夜福利理论片高清在线观看| 亚洲精品一品区二品区三品区| 久久本色成人综合网| 亚洲日韩一中文字暮av| 无码国产精品久久一区免费| 国产av无码专区国产乱码| 成人精品一区日本无码网站| 2020久久国产综合精品swag| 亚洲国产欧美在线人成| 久久精品国产亚洲精品|