在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PLIN5 Antibody, FITC conjugated

PLIN5 Antibody, FITC conjugated

  • 中文名稱：
    PLIN5兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA804867LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PLIN5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Lipid storage droplet protein 5 antibody; LSDA5 antibody; MLDP antibody; OXPAT antibody; Perilipin 5 antibody; Perilipin-5 antibody; PLIN5 antibody; PLIN5_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Perilipin-5 protein (305-453AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE.
  • 基因功能參考文獻：
    1. The data highlight a key role of PLIN5 in lipid droplets function, first by finely adjusting lipid droplets fatty acids supply to mitochondrial oxidation, and second acting as a protective factor against lipotoxicity in skeletal muscle. PMID: 27922115
    2. Notch1 expression is reduced and glucose-6-phosphatase and perilipin-5 (G6PC/PLIN5) are upregulated in liver biopsies from nonalcoholic steatohepatitis (NASH) and nonalcoholic fatty liver disease (NAFLD) patients. PMID: 27428080
    3. High oxygen consumption in middle-aged men was reflected in higher perilipin 5 expression in skeletal muscle. PMID: 26447519
    4. PLIN5 was significantly colocated with ATGL, mitochondria and CGI-58, indicating a close association between the key lipolytic effectors in resting skeletal muscle. PMID: 25054327
    5. Perilipin 5 as a lipid droplet protein adapted to mitochondrial energy utilization PMID: 24535284
    6. Sprint interval and traditional endurance training increase net intramuscular triglyceride breakdown and expression of perilipin 2 and 5 PMID: 23129790
    7. PLIN5 likely plays an important role in intramyocellular lipid accumulation and oxidation, both of which increase with endurance training in human skeletal muscle. PMID: 22667335
    8. The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria. PMID: 22127648
    9. Perilipin 5 is the most recently established family member, highly expressed in oxidative tissues and could play an important role in regulating LD TAG hydrolysis in oxidative mammalian tissues. [Review] PMID: 21632259
    10. interaction of ATGL with CGI-58 increased lipolysis, whereas interaction of ATGL with perilipin 5 decreased lipolysis. PMID: 21393244
    11. Results indicate involvement of OXPAT and ADRP in muscular lipid accumulation and type 2 diabetes. PMID: 19602560

    顯示更多

    收起更多

  • 亞細胞定位：
    Lipid droplet. Cytoplasm. Mitochondrion.
  • 蛋白家族：
    Perilipin family
  • 組織特異性：
    Expressed in skeletal muscle, liver, heart and kidney.
  • 數據庫鏈接：

    HGNC: 33196

    OMIM: 613248

    KEGG: hsa:440503

    STRING: 9606.ENSP00000371272

    UniGene: Hs.131034



主站蜘蛛池模板： 小泽玛利亚一区二区在线观看| 国产精欧美一区二区三区| 国产乱人伦偷精品视频不卡| 久久精品一区二区三区av| 亚洲精品成人片在线观看精品字幕| 777精品久无码人妻蜜桃| 亚洲另类无码专区丝袜| 又黄又爽又高潮免费毛片| 亚洲香蕉网久久综合影视| 亚洲人成手机电影网站| 亚洲精品成人福利网站app| 色妺妺视频网| 狠狠综合久久av一区二区| 久久综合亚洲色hezyo国产 | 97人妻无码一区| 久久九九精品国产av片国产| 欧洲国产精品无码专区影院| 国产欧美va天堂在线观看视频下载 | 日本欧美一区二区三区乱码| 鲁大师影院在线观看| 99riav国产精品视频| 国产粗话肉麻对白在线播放| 久久无码喷吹高潮播放不卡| 大胸少妇午夜三级| 国产精品久久久久久久久ktv| 亚洲国产成人一区二区在线| 青青青国产免a在线观看| 日韩少妇激情一区二区| 精品国产三级a∨在线欧美| 国产精品久久久久久无码| 亚洲伊人丝袜精品久久| 忘忧草影院在线www韩国日本| 精品久久久久久久无码| 亚洲日韩av一区二区三区四区| 亚洲中文久久精品无码照片| 成人女人黄网站免费视频| 性xxxx欧美老妇胖老太性多毛| 色狠狠成人综合网| 国产 精品 自在 线免费| 国产av毛片亚洲含羞草社| 国产人妻人伦精品久久久|