在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PLEKHG5 Antibody, FITC conjugated

PLEKHG5 Antibody, FITC conjugated

  • 中文名稱：
    PLEKHG5兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA018174LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PLEKHG5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PLEKHG5
  • 別名：
    PLEKHG5 antibody; KIAA0720 antibody; Pleckstrin homology domain-containing family G member 5 antibody; PH domain-containing family G member 5 antibody; Guanine nucleotide exchange factor 720 antibody; GEF720 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Pleckstrin homology domain-containing family G member 5 protein (821-957AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Functions as a guanine exchange factor (GEF) for RAB26 and thus regulates autophagy of synaptic vesicles in axon terminal of motoneurons. Involved in the control of neuronal cell differentiation. Plays a role in angiogenesis through regulation of endothelial cells chemotaxis. Affects also the migration, adhesion, and matrix/bone degradation in macrophages and osteoclasts.
  • 基因功能參考文獻：
    1. Results indicate that different mutations in PLEKHG5 lead to clinically diverse outcomes Charcot-Marie-Tooth disease or lower motor neuron disease affecting the function of neurons and glial cells. PMID: 23777631
    2. Recruitment of Syx to the cell membrane, the selective activation of Dia1 signaling, coupled with the suppression of ROCK and actin reorganization, plays a key role in establishing cell polarity during directed cell migration. PMID: 24126053
    3. This study identifies compound heterozygous PLEKHG5 mutations as the cause of recessive intermediate Charcot-Marie-Tooth disease. PMID: 23844677
    4. a novel means of regulating junctional Syx localization and function by phosphorylation-induced 14-3-3 binding and further support the importance of Syx function in maintaining stable cell-cell contacts. PMID: 23335514
    5. We identified a homozygous missense mutation (c.1940 T-->C [p.647 Phe-->Ser]) of the Pleckstrin homology domain-containing, family G member 5 gene, PLEKHG5, in families with lower motor neuron disease. PMID: 17564964

    顯示更多

    收起更多

  • 相關疾病：
    Distal spinal muscular atrophy, autosomal recessive, 4 (DSMA4); Charcot-Marie-Tooth disease, recessive, intermediate type, C (CMTRIC)
  • 亞細胞定位：
    Cytoplasm. Cytoplasm, perinuclear region. Cell membrane. Cell junction. Cell projection, lamellipodium.
  • 組織特異性：
    Predominantly expressed in the peripheral nervous system and brain. Highest expression is observed in heart, lung, kidney, testis and moderate expression is present in spleen, pancreas, skeletal muscle, ovary and liver. Weakly expressed in glioblastoma (G
  • 數(shù)據(jù)庫鏈接：

    HGNC: 29105

    OMIM: 611067

    KEGG: hsa:57449

    STRING: 9606.ENSP00000366977

    UniGene: Hs.284232



主站蜘蛛池模板： 99久久久无码国产精品6 | 寂寞骚妇被后入式爆草抓爆| 五月激激激综合网亚洲| 日韩丝袜欧美人妻制服| 九九线精品视频在线观看| 亚洲愉拍自拍另类天堂| 67194成是人免费无码| 人妻熟人中文字幕一区二区| 亚洲中文字幕在线第二页| 97超碰中文字幕久久精品| 久久久久麻豆v国产精华液好用吗| 亚洲爆乳大丰满无码专区| 狂野av人人澡人人添| 亚洲乱码一卡二卡卡3卡4卡| 大胸少妇午夜三级| 无码精品人妻一区二区三区免费看| 亚洲成av人在线视猫咪| 亚洲欧洲日产无码中文字幕| 亚洲精品成人网站在线| 国产裸拍裸体视频在线观看| 亚洲第一区无码专区| 偷看农村妇女牲交| 噜噜色综合天天综合网mp3| 欧美大屁股熟妇bbbbbb| 久久久久久a亚洲欧洲av| 人人妻人人澡人人爽国产| 99久久九九社区精品| 少妇粗大进出白浆嘿嘿视频| 日本55丰满熟妇厨房伦| 日本熟妇色一本在线观看| 无码熟熟妇丰满人妻porn| 我把护士日出水了视频90分钟| 亚洲熟女综合一区二区三区| 乱子伦av无码中文字| 亚洲中文字幕无码永久在线不卡| 国产白袜脚足j棉袜在线观看| 真人做人试看60分钟免费视频| 牲高潮99爽久久久久777| 国产精品久久久久无码av色戒| 国产精品无码av天天爽| 久久se精品一区二区三区|