在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PKP4 Antibody

  • 中文名稱:
    PKP4兔多克隆抗體
  • 貨號:
    CSB-PA018083GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    PKP4
  • 別名:
    Catenin 4 antibody; Catenin4 antibody; FLJ31261 antibody; FLJ42243 antibody; p0071 antibody; PKP 4 antibody; PKP4 antibody; PKP4_HUMAN antibody; Plakophilin 4 antibody; Plakophilin-4 antibody; Plakophilin4 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human PKP4
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Plays a role as a regulator of Rho activity during cytokinesis. May play a role in junctional plaques.
  • 基因功能參考文獻:
    1. p0071 is required for directional vesicle movement and secretion of different KIF3-transported carriers, thereby regulating the transport of intracellular membrane vesicles along microtubules. PMID: 28808088
    2. Data show that patients with both abnormal expression of p0071 and E-cadherin had a statistically significant shorter survival than the patients without both abnormal expression. PMID: 28898462
    3. p0071 has a key role in regulating recycling through the Rab11a-dependent perinuclear recycling compartment. PMID: 24163434
    4. This review article focuses on the functions of the p0071 protein and its closest relatives in regulating cell adhesion and cytoskeletal organization, which are critically involved in the control of cell polarity. [review] PMID: 23640939
    5. Findings suggest that aspects of folliculin tumour suppressor function are linked to interaction with p0071 and the regulation of RhoA signalling. PMID: 22965878
    6. These data support a model in which dysregulation of the FLCN-p0071 interaction leads to alterations in cell adhesion, cell polarity, and RhoA signaling. PMID: 23139756
    7. The structural and functional roles of p0071 are suggested by its preferential occurrence in distinct tubule segments, and its potential use as a cytodiagnostic cell type marker in renal pathology is discussed. PMID: 19830446
    8. ERBIN interacts in vivo with p0071 and that it may be involved in the organization of adherens junctions and the desmosomes of epithelia PMID: 12047349
    9. In addition to plakoglobin, p0071 is the second armadillo protein present in both types of adhesive junctions and may play a role in regulating crosstalk between adherens junctions and desmosomes. PMID: 12615965
    10. p0071 bound to the first 160 amino-terminal residues of desmoplakin and also interacted directly with plakoglobin, suggesting that p0071 may regulate desmosome assembly by controlling plakoglobin availability PMID: 15304078
    11. These findings support an essential role for p0071 in spatially regulating restricted Rho signalling during cytokinesis. PMID: 17115030
    12. In this review p0071 catenin, a close relative of p120 catenin, associates and regulates RhoA-GTPase at the cleavage furrow during cytokinesis. PMID: 17264675
    13. Protein p0071 has been localized as a plaque protein in adhaerens junctions of diverse epithelia and certain vascular endothelia. PMID: 19005682
    14. Data indicate that p0071 and Ect2 are transported via distinct motors and identify a novel pathway implicating KIF3 in the regulation of actin organization during cytokinesis. PMID: 19339549

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell junction, desmosome. Cytoplasm, cytoskeleton, spindle. Midbody. Cell membrane; Peripheral membrane protein. Note=Associated with the pericentrosomal region in interphase and with spindle poles during mitosis. In anaphase, during chromosome segregation, is recruited to the central microtubule bundle, focussed at the spindle midzone and ultimately localizes to the midbody at cytokinesis. Constituent of the midbody cytoskeletal matrix. Colocalized with desmoplakin at desmosomal junctional plaques in cultured epithelial cells.
  • 蛋白家族:
    Beta-catenin family
  • 數據庫鏈接:

    HGNC: 9026

    OMIM: 604276

    KEGG: hsa:8502

    STRING: 9606.ENSP00000374409

    UniGene: Hs.407580



主站蜘蛛池模板: 国产精品亚洲精品日韩已满十八小| 亚洲精品永久在线观看| 国产日韩综合一区二区性色av| 亚洲综合av色婷婷五月蜜臀| 国内精品久久久久久久影视麻豆| 国产青榴视频在线观看| 久久久久无码国产精品不卡| 国产av激情久久无码天堂| 成 人 免 费 黄 色| 国产一起色一起爱| 国模冰莲极品自慰人体| 国产精品进线69影院| 日产2021免费一区| 国产乱人伦无无码视频试看| 亚洲国产av无码精品无广告| 美乳丰满人妻无码视频| 顶级欧美熟妇高潮xxxxx| 人妻无码中文久久久久专区| 人人妻人人添人人爽欧美一区| 国产日产欧产精品精品免费| 国产 制服丝袜 动漫在线| 久本草在线中文字幕亚洲| 无码精品日韩中文字幕| 久久久噜噜噜久久熟女| 强行无套内谢大学生初次| 亚洲啪啪综合av一区| 99re久久资源最新地址| 国产69精品久久久久乱码韩国| 国产激情艳情在线看视频| 久久/这里只精品热在线获取| 日日摸日日碰夜夜爽无码| 麻豆国产一区二区三区四区| 人妻中文字幕乱人伦在线| 午夜成人无码片在线观看影院| 五十路丰满中年熟女中出| 成年性生交大片免费看| 亚洲欧美色αv在线影视| 亚洲欧美成人中文日韩电影网站| 中文无码乱人伦中文视频在线v| 欧美激情乱人伦| 欧美成人天天综合在线|