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PITPNA Antibody

  • 中文名稱：
    PITPNA兔多克隆抗體
  • 貨號：
    CSB-PA018035LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA018035LA01HU diluted at 1:100 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of U251 cells with CSB-PA018035LA01HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PITPNA Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PITPNA
  • 別名：
    MGC99649 antibody; Phosphatidylinositol transfer protein alpha antibody; Phosphatidylinositol transfer protein alpha isoform antibody; Phosphotidylinositol transfer protein antibody; PI-TP-alpha antibody; PIPNA_HUMAN antibody; PITP alpha antibody; Pitpna antibody; PITPNB antibody; PtdIns transfer protein alpha antibody; PtdInsTP alpha antibody; PtdInsTP antibody; Vb antibody; VIB1A antibody; Vibrator antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Phosphatidylinositol transfer protein alpha isoform protein (1-270AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，PITPNA Antibody (CSB-PA018035LA01HU)，的標記方式是Non-conjugated。對于PITPNA Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA018035LB01HU PITPNA Antibody, HRP conjugated ELISA
    FITC CSB-PA018035LC01HU PITPNA Antibody, FITC conjugated
    Biotin CSB-PA018035LD01HU PITPNA Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes. Shows a preference for PI and PC containing shorter saturated or monosaturated acyl chains at the sn-1 and sn-2 positions. Preference order for PC is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 and for PI is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 > C20:3.
  • 基因功能參考文獻：
    1. Data show that phosphatidylinositol transfer protein alpha (PITPalpha) is involved in the function of mixed lineage kinase domain-like protein (MLKL) in necroptosis. PMID: 29104146
    2. the PITPalpha structure has to relax to allow access to the Ser166 site, and this may occur at the membrane surface where PI delivery is required for receptor-mediated PLC signaling PMID: 15322105
    3. the apparent occurrence of an unusual TG 3' splice site in intron 4 is discussed PMID: 17672918
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    PtdIns transfer protein family, PI transfer class I subfamily
  • 數據庫鏈接：

    HGNC: 9001

    OMIM: 600174

    KEGG: hsa:5306

    STRING: 9606.ENSP00000316809

    UniGene: Hs.429819



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