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  4. PITPNA Antibody

PITPNA Antibody

  • 中文名稱：
    PITPNA兔多克隆抗體
  • 貨號：
    CSB-PA030063
  • 規格：
    ￥1090
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    PITPNA
  • 別名：
    MGC99649 antibody; Phosphatidylinositol transfer protein alpha antibody; Phosphatidylinositol transfer protein alpha isoform antibody; Phosphotidylinositol transfer protein antibody; PI-TP-alpha antibody; PIPNA_HUMAN antibody; PITP alpha antibody; Pitpna antibody; PITPNB antibody; PtdIns transfer protein alpha antibody; PtdInsTP alpha antibody; PtdInsTP antibody; Vb antibody; VIB1A antibody; Vibrator antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human PITPα.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:10000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes. Shows a preference for PI and PC containing shorter saturated or monosaturated acyl chains at the sn-1 and sn-2 positions. Preference order for PC is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 and for PI is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 > C20:3.
  • 基因功能參考文獻：
    1. Data show that phosphatidylinositol transfer protein alpha (PITPalpha) is involved in the function of mixed lineage kinase domain-like protein (MLKL) in necroptosis. PMID: 29104146
    2. the PITPalpha structure has to relax to allow access to the Ser166 site, and this may occur at the membrane surface where PI delivery is required for receptor-mediated PLC signaling PMID: 15322105
    3. the apparent occurrence of an unusual TG 3' splice site in intron 4 is discussed PMID: 17672918
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    PtdIns transfer protein family, PI transfer class I subfamily
  • 數據庫鏈接：

    HGNC: 9001

    OMIM: 600174

    KEGG: hsa:5306

    STRING: 9606.ENSP00000316809

    UniGene: Hs.429819



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