在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PDE9A Antibody

PDE9A Antibody

  • 中文名稱：
    PDE9A兔多克隆抗體
  • 貨號：
    CSB-PA527985GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PDE9A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PDE9A
  • 別名：
    5''-cyclic phosphodiesterase 9A antibody; cGMP specific 3' 5' cyclic phosphodiesterase type 9 antibody; FLJ90181 antibody; High affinity cGMP-specific 3'' antibody; High-affinity cGMP-specific 3'5'-cyclic phosphodiesterase 9A antibody; HSPDE9A2 antibody; OTTHUMP00000109399 antibody; PDE 9A antibody; Pde9a antibody; PDE9A_HUMAN antibody; Phosphodiesterase 9A antibody; phosphodiesterase PDE9A21 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human PDE9A protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP. Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart. Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein (Probable). In brain, involved in cognitive function, such as learning and long-term memory.
  • 基因功能參考文獻：
    1. PDE9A can regulate cGMP signalling independent of the nitric oxide pathway, and its role in stress-induced heart disease suggests potential as a therapeutic target. PMID: 25799991
    2. it is concluded that assessment of PDE5 and PDE9 expression may be useful in the differential diagnosis of benign and malignant breast disease and successful treatment of breast cancer PMID: 22960860
    3. In vivo effects of PDE9A inhibition included reversal of the respective disruptions of working memory. PMID: 22328573
    4. PDE9 is widely distributed in the urothelial epithelium of the human lower urinary tract and its potential roles may be different from those of PDE5. PMID: 21736695
    5. Data show that PDE9A inhibitor, BAY-73-6691, significantly reduced basal and sickle cell (SCA) neutrophil adhesion; this was accompanied by decreased SCA neutrophil surface expressions of the L-selectin and CD11b adhesion molecules. PMID: 21336703
    6. Identification and distribution of different variants produced by differential splicing of phosphodiesterase 9A mRNA. PMID: 12565835
    7. X ray crystallography with IBMX inhibitor binding PMID: 15210993
    8. The data suggests the utilization of two different start codons to produce a variety of different PDE9A proteins, allowing specific subcellular location of PDE9A splice variants. PMID: 17090334
    9. PDE9A, is unlikely to play an important role in antidepressant outcome in this sample PMID: 19214142

    顯示更多

    收起更多

  • 亞細胞定位：
    [Isoform PDE9A1]: Cell projection, ruffle membrane. Cytoplasm, perinuclear region. Golgi apparatus. Endoplasmic reticulum. Cell membrane, sarcolemma.; [Isoform PDE9A2]: Cell projection, ruffle membrane. Cytoplasm, perinuclear region.; [Isoform PDE9A3]: Cytoplasm. Endoplasmic reticulum.; [Isoform PDE9A17]: Cytoplasm. Endoplasmic reticulum.
  • 蛋白家族：
    Cyclic nucleotide phosphodiesterase family, PDE9 subfamily
  • 組織特異性：
    Expressed in all tissues examined (testis, brain, small intestine, skeletal muscle, heart, lung, thymus, spleen, placenta, kidney, liver, pancreas, ovary and prostate) except blood. Highest levels in brain, heart, kidney, spleen, prostate and colon. Isofo
  • 數(shù)據庫鏈接：

    HGNC: 8795

    OMIM: 602973

    KEGG: hsa:5152

    STRING: 9606.ENSP00000291539

    UniGene: Hs.473927



主站蜘蛛池模板： 国产高潮抽搐喷水高清| 久久亚洲精品成人av| 中文字幕无线码免费人妻| 久久成人国产精品免费| 中文字幕久久精品一区二区三区| 久久人人爽爽人人爽人人片av| 凹凸国产熟女精品视频app| 成人伊人亚洲人综合网站| 大屁股国产白浆一二区| 精品国模一区二区三区| 国产精品久久..4399| 国产精品国产三级国av麻豆 | 在线看片无码永久av| 亚洲欧洲自拍拍偷精品网 | 亚洲视频一区| 囯产精品一品二区三区| 日本道免费精品一区二区| 日本乱妇乱子视频| 东京热无码av一区二区| 国产精品久久久久久亚洲影视| 亚洲性色av性色在线观看| 国产在线观看无码免费视频| 久久电影网午夜鲁丝片免费 | 国产精品中文久久久久久久| 精品一区二区三区免费视频| 国产福利男女xx00视频| 亚洲区激情区无码区日韩区| 2021国产精品自在自线| 九九九国产精品成人免费视频 | 精品国产成人网站一区在线| 成年性午夜免费视频网站| 欧美成人va免费看视频| 国内少妇偷人精品视频| 色婷婷亚洲一区二区三区| 在线播放无码后入内射少妇| 国产高清视频色拍| 国精产品一品二品国精在线观看| 插我舔内射18免费视频| 中文字幕久精品免费视频| 亚洲精品无播放器在线播放| 97影院理论片手机在线观看 |