在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PDE9A Antibody, HRP conjugated

PDE9A Antibody, HRP conjugated

  • 中文名稱：
    PDE9A兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA527985LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PDE9A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PDE9A
  • 別名：
    5''-cyclic phosphodiesterase 9A antibody; cGMP specific 3' 5' cyclic phosphodiesterase type 9 antibody; FLJ90181 antibody; High affinity cGMP-specific 3'' antibody; High-affinity cGMP-specific 3'5'-cyclic phosphodiesterase 9A antibody; HSPDE9A2 antibody; OTTHUMP00000109399 antibody; PDE 9A antibody; Pde9a antibody; PDE9A_HUMAN antibody; Phosphodiesterase 9A antibody; phosphodiesterase PDE9A21 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A protein (426-533AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP. Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart. Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein (Probable). In brain, involved in cognitive function, such as learning and long-term memory.
  • 基因功能參考文獻：
    1. PDE9A can regulate cGMP signalling independent of the nitric oxide pathway, and its role in stress-induced heart disease suggests potential as a therapeutic target. PMID: 25799991
    2. it is concluded that assessment of PDE5 and PDE9 expression may be useful in the differential diagnosis of benign and malignant breast disease and successful treatment of breast cancer PMID: 22960860
    3. In vivo effects of PDE9A inhibition included reversal of the respective disruptions of working memory. PMID: 22328573
    4. PDE9 is widely distributed in the urothelial epithelium of the human lower urinary tract and its potential roles may be different from those of PDE5. PMID: 21736695
    5. Data show that PDE9A inhibitor, BAY-73-6691, significantly reduced basal and sickle cell (SCA) neutrophil adhesion; this was accompanied by decreased SCA neutrophil surface expressions of the L-selectin and CD11b adhesion molecules. PMID: 21336703
    6. Identification and distribution of different variants produced by differential splicing of phosphodiesterase 9A mRNA. PMID: 12565835
    7. X ray crystallography with IBMX inhibitor binding PMID: 15210993
    8. The data suggests the utilization of two different start codons to produce a variety of different PDE9A proteins, allowing specific subcellular location of PDE9A splice variants. PMID: 17090334
    9. PDE9A, is unlikely to play an important role in antidepressant outcome in this sample PMID: 19214142

    顯示更多

    收起更多

  • 亞細胞定位：
    [Isoform PDE9A1]: Cell projection, ruffle membrane. Cytoplasm, perinuclear region. Golgi apparatus. Endoplasmic reticulum. Cell membrane, sarcolemma.; [Isoform PDE9A2]: Cell projection, ruffle membrane. Cytoplasm, perinuclear region.; [Isoform PDE9A3]: Cytoplasm. Endoplasmic reticulum.; [Isoform PDE9A17]: Cytoplasm. Endoplasmic reticulum.
  • 蛋白家族：
    Cyclic nucleotide phosphodiesterase family, PDE9 subfamily
  • 組織特異性：
    Expressed in all tissues examined (testis, brain, small intestine, skeletal muscle, heart, lung, thymus, spleen, placenta, kidney, liver, pancreas, ovary and prostate) except blood. Highest levels in brain, heart, kidney, spleen, prostate and colon. Isofo
  • 數據庫鏈接：

    HGNC: 8795

    OMIM: 602973

    KEGG: hsa:5152

    STRING: 9606.ENSP00000291539

    UniGene: Hs.473927



主站蜘蛛池模板： 女人下边被添全过视频的网址| 国产亚洲精品久久久闺蜜| 欧美搡bbbbb搡bbbbb| 久久一日本道色综合久久| 国产精品无码a∨精品影院app| 日本强伦姧人妻久久影片| 天堂无码人妻精品av一区| 野外做受又硬又粗又大视频| 欧美精品欧美人与动人物牲交| av不卡国产在线观看| 国产欧美va天堂在线观看视频下载| 国产麻豆精品一区二区三区v视界| 亚洲欧美日韩中文播放| 日本大片免费观看视频| 五月婷婷久久草丁香| 97午夜理论片在线影院| 免费无码黄动漫十八禁| 亚洲欲色欲色xxxxx在线| www一区二区www免费| 在线中文字幕乱码英文字幕正常| 精品av中文字幕在线毛片| а√天堂8资源在线官网| 国产精品久久久久久一区二区三区| 思思99re6国产在线播放| 亚洲国产成人综合在线不卡| 国产猛烈高潮尖叫视频免费| 最近免费中文字幕中文高清百度| 亚洲精品日韩一区二区小说| 免费的av网站手机版| 国产成人无码18禁午夜福利p| 亚洲 另类 日韩 制服 无码| awww在线天堂bd资源在线| 性做久久久久久久久| 日本又色又爽又黄的a片吻戏| 奇米777狠狠色噜噜狠狠狠| 日本熟人妻中文字幕在线| 国产69精品久久久久久久| 五月激激激综合网亚洲| 亚洲成a人片在线观看日本| 国产精品9999久久久久仙踪林| 日本午夜精品一区二区三区电影|