在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PDE6D Antibody, HRP conjugated

PDE6D Antibody, HRP conjugated

  • 中文名稱：
    PDE6D兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA526126LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PDE6D Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PDE6D
  • 別名：
    5''-cyclic phosphodiesterase subunit delta antibody; GMP PDE delta antibody; GMP-PDE delta antibody; p17 protein antibody; PDE 6 antibody; PDE 6D antibody; PDE D antibody; PDE6 antibody; PDE6D antibody; PDE6D_HUMAN antibody; PDED antibody; Phosphodiesterase 6D cGMP specific antibody; Phosphodiesterase 6D cGMP specific rod delta antibody; Protein p17 antibody; Retinal rod photoreceptor cGMP phosphodiesterase delta antibody; Retinal rod rhodopsin sensitive cGMP 3' 5' cyclic phosphodiesterase subunit delta antibody; Retinal rod rhodopsin-sensitive cGMP 3'' antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Retinal rod rhodopsin-sensitive cGMP 3\',5\'-cyclic phosphodiesterase subunit delta protein (1-150AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.
  • 基因功能參考文獻(xiàn)：
    1. PDE6delta binds selectively to the C-terminus of RPGR and that this interaction is critical for RPGR's localization to cilia. PMID: 28172980
    2. Studies indicate that the binding of UNC119 and PDE6D, to the lipid-modified ciliary cargo and the specific release of the cargo in the cilia by the ciliary small G-protein Arl3 in a GTP-dependent manner. PMID: 27911709
    3. Study identifies PDE6D as a novel Joubert syndrome gene and provides the first evidence of prenyl-binding-dependent trafficking in ciliopathies. PMID: 24166846
    4. RPGR is acting as a scaffold protein recruiting cargo-loaded PDE6D and Arl3 to release lipidated cargo into cilia. PMID: 23559067
    5. findings indicate that ARL13B, INPP5E, PDE6D, and CEP164 form a distinct functional network that is involved in JBTS and NPHP but independent of the ones previously defined by NPHP and MKS proteins PMID: 23150559
    6. Data show that PDEdelta activity augments K/Hras signalling by enriching Ras at the plasma membrane. PMID: 22179043

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Joubert syndrome 22 (JBTS22)
  • 亞細(xì)胞定位：
    Cytoplasm, cytosol. Cytoplasmic vesicle membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族：
    PDE6D/unc-119 family
  • 組織特異性：
    Widely expressed. Detected in various tissues including spleen, prostate gland, testis, ovary, small intestine, colon, retina, and peripheral blood.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 8788

    OMIM: 602676

    KEGG: hsa:5147

    STRING: 9606.ENSP00000287600

    UniGene: Hs.516808



主站蜘蛛池模板： 中文字幕无码日韩中文字幕| 亚洲愉拍99热成人精品热久久| 中文字幕乱人伦高清视频| 人人妻人人澡人人爽人人dvd| 国产成人无码精品久久久露脸| 真实国产乱子伦在线视频| 亚洲人成无码区在线观看| 美女黄18以下禁止观看| 韩国三级hd中文字幕叫床| 亚洲成在人线免费观看| 中文字幕在线免费看线人| 亚洲人成色77777在线观看| 风韵丰满熟妇啪啪区老老熟女百度| 奇米综合四色77777久久| 少妇与黑人一二三区无码| 国产又黄又硬又粗| 老色69久久九九精品高潮| 亚洲国产精品无码久久秋霞| 麻豆自媒体 一区 二区| 国产av激情无码久久| 久久zyz资源站无码中文动漫| 久久成人a毛片免费观看网站| 免费国产高清在线精品一区| 国产欧洲精品自在自线官方| 亚洲精品无码av人在线观看| 日韩无码专区| 动漫av纯肉无码av在线播放| 日本三级香港三级三级人!妇久| 免费福利视频一区二区三区高清| 欧美最猛性xxxxx大叫| 青青国产揄拍视频| 日产亚洲一区二区三区| 国产成人综合久久亚洲精品| 国产午夜福利视频在线观看| 欧美变态口味重另类在线视频 | 久久综合亚洲欧美成人| 午夜成人影院网站18进| 中文字幕无码av正片| 在线观看国产成人av天堂| 久久精品午夜福利| 国精产品一品二品国精在线观看|