在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PC Antibody, HRP conjugated

PC Antibody, HRP conjugated

  • 中文名稱(chēng)：
    PC兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào)：
    CSB-PA017511LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) PC Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    mitochondrial antibody; OTTHUMP00000235155 antibody; OTTHUMP00000235156 antibody; PC antibody; PCB antibody; Pcx antibody; PYC_HUMAN antibody; Pyruvate carboxylase antibody; Pyruvate carboxylase mitochondrial antibody; Pyruvic carboxylase antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Pyruvate carboxylase, mitochondrial protein (773-1007AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate.
  • 基因功能參考文獻(xiàn)：
    1. PC enzyme activity is much higher in the highly invasive breast cancer cell line MDA-MB-231 than in less invasive breast cancer cell lines. Strong PC suppression lowered glucose incorporation into downstream metabolites of oxaloacetate, the product of the PC reaction, including malate, citrate and aspartate. PMID: 27890529
    2. breast cancer cells proliferating as lung metastases activate PC-dependent anaplerosis in response to the lung microenvironment. PMID: 27732858
    3. Pyruvate carboxylase activates the RIG-I-like receptor-mediated antiviral immune response by targeting the MAVS signalosome. PMID: 26906558
    4. PC and PDH may be an important part of cellular adaptation to the IDH1 mutation and may serve as potential therapeutic targets PMID: 25243911
    5. These findings indicate that PC-mediated anaplerosis in early-stage NSCLC is required for tumor survival and proliferation. PMID: 25607840
    6. Increased PC expression is correlated with the malignant progression of GC, which might be a potential target for GC biotherapy. PMID: 23294723
    7. characterization of PC distal promoter PMID: 23383084
    8. PC protein is easily detectable by streptavidin blot and the presence of considerable amounts of PC in cultured human myotubes and in human muscle tissue was shown. PMID: 20807508
    9. IVS15+2-5delTAGG results in the retention of intron 15 during pre-mRNA splicing and frameshift mutations. PMID: 12112657
    10. expression and characterization of a variant by retroviral gene transfer PMID: 12437512
    11. 1 deficiency patient survived from neonatal lactic acidemia and shows an unusual subcortical leucodystrophic process. PMID: 16325442
    12. The crystal structures at 2.8-A resolution of full-length PC from Staphylococcus aureus and the C-terminal region (missing only the BC domain) of human PC, is reported. PMID: 18297087
    13. Eight novel mutations were identified in PC from 8 pyruvate carboxylase deficiency patients. PMID: 18676167
    14. The activities of pyruvate carboxylase (PC) were decreased by 65% in pancreatic islets of patients with type 2 diabetes. PMID: 19296078
    15. Nine novel mutations of the PC gene, in five unrelated patients, are reported. PMID: 19306334

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Pyruvate carboxylase deficiency (PC deficiency)
  • 亞細(xì)胞定位：
    Mitochondrion matrix.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 8636

    OMIM: 266150

    KEGG: hsa:5091

    STRING: 9606.ENSP00000377527

    UniGene: Hs.89890



主站蜘蛛池模板： 国产日韩精品视频无码| 精品无码久久久久国产手机版| 天堂最新版资源网| 日本亚州视频在线八a| 国产狂喷潮在线观看| 永久免费看mv网站入口亚洲| 久久综合给综合给久久| 日日摸日日碰夜夜爽亚洲综合| 日韩好精品视频你懂的| 国产精品水嫩水嫩| а√天堂资源中文在线官网| 99热久久这里只精品国产www| 真实国产熟睡乱子伦视频| 国产97色在线 | 亚洲| 亚洲不乱码卡一卡二卡4卡5 | 无码av不卡免费播放| 久99久热只有精品国产15| 秋霞午夜成人久久电影网| 无码专区—va亚洲v专区vr| 亚洲国产成人精品无码区二本| 99久久人人爽亚洲精品美女| 无码专区久久综合久中文字幕| 欧美一区二区| 色www永久免费视频首页| 18禁美女裸体无遮挡免费观看国产| 蜜桃臀无码内射一区二区三区| 久久精品亚洲日本波多野结衣| 五月丁香六月激情综合在线视频 | 2021国产精品一卡2卡三卡4卡| 亚洲乱码日产精品bd在| 中文字幕在线日亚洲9| 精品产区wnw2544| 欧美饥渴熟妇高潮喷水| 国产午夜草莓视频在线观看| 丰满的少妇xxxxx青青青| 亚洲国产精品久久久久婷蜜芽| 色婷婷狠狠97成为人免费| 国产成人综合色就色综合| 亚洲日本va午夜在线电影| 动漫精品无码h在线观看| 国内精品一区二区三区|