在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

OPN3 Antibody

  • 中文名稱:
    OPN3兔多克隆抗體
  • 貨號:
    CSB-PA872435LA01HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • IHC image of CSB-PA872435LA01HU diluted at 1:300 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of A549 cells with CSB-PA872435LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) OPN3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    OPN3; ECPN; Opsin-3; Encephalopsin; Panopsin
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Opsin-3 protein (313-402AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated

    本頁面中的產(chǎn)品,OPN3 Antibody (CSB-PA872435LA01HU),的標(biāo)記方式是Non-conjugated。對于OPN3 Antibody,我們還提供其他標(biāo)記。見下表:

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA872435LB01HU OPN3 Antibody, HRP conjugated ELISA
    FITC CSB-PA872435LC01HU OPN3 Antibody, FITC conjugated
    Biotin CSB-PA872435LD01HU OPN3 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IHC, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    G-protein coupled receptor which selectively activates G proteins via ultraviolet A (UVA) light-mediated activation in the skin. Binds both 11-cis retinal and all-trans retinal. Regulates melanogenesis in melanocytes via inhibition of alpha-MSH-induced MC1R-mediated cAMP signaling, modulation of calcium flux, regulation of CAMK2 phosphorylation, and subsequently phosphorylation of CREB, p38, ERK and MITF in response to blue light. Plays a role in melanocyte survival through regulation of intracellular calcium levels and subsequent BCL2/RAF1 signaling. Additionally regulates apoptosis via cytochrome c release and subsequent activation of the caspase cascade. Required for TYR and DCT blue light-induced complex formation in melanocytes. Involved in keratinocyte differentiation in response to blue-light. Required for the UVA-mediated induction of calcium and mitogen-activated protein kinase signaling resulting in the expression of MMP1, MMP2, MMP3, MMP9 and TIMP1 in dermal fibroblasts. Plays a role in light-mediated glucose uptake, mitochondrial respiration and fatty acid metabolism in brown adipocyte tissues. May be involved in photorelaxation of airway smooth muscle cells, via blue-light dependent GPCR signaling pathways.
  • 基因功能參考文獻(xiàn):
    1. Decreased OPN3 levels in Bel7402(5-FU) cells activated the anti-apoptotic pathway through increasing phospho-Akt and the Bcl2/Bax ratio, while overexpression of OPN3 inactivated this pathway. PMID: 22313545
    2. Assignment of panopsin (OPN3) to human chromosome band 1q43 PMID: 12063405
    3. Human OPN3 gene consists of six exons and expresses various splice variants. PMID: 12242008
    4. Polymorphisms in the OPN3 and CHML genes are associated with asthma and atopic asthma. PMID: 18344558
    5. Related persons with heterozygous germline deletions of 1q42.3, which includes EXO1, RGS7, KMO, CHML, and OPN3, showed no phenotypic abnormalities other than multiple leiomyomatosis. PMID: 14623461

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cell membrane; Multi-pass membrane protein. Cytoplasm.
  • 蛋白家族:
    G-protein coupled receptor 1 family, Opsin subfamily
  • 組織特異性:
    Expressed in tracheal airway smooth muscle (at protein level). Expressed throughout the epidermis and dermis, predominantly in the basal layer on the facial and abdominal skin (at protein level). Expressed in dermal fibroblasts (at protein level). Express
  • 數(shù)據(jù)庫鏈接:

    HGNC: 14007

    OMIM: 606695

    KEGG: hsa:23596

    STRING: 9606.ENSP00000355512

    UniGene: Hs.409081



主站蜘蛛池模板: 精品国产乱码久久久久久影片| 欧美成aⅴ人高清免费观看| 色欲天天天无码视频| 亚洲日韩中文字幕在线播放| 中文无码一区二区不卡αv| 免费观看的av在线播放 | 欧美成aⅴ人高清免费| 欧美肥臀大屁股magnet| 国产精品毛片一区二区三区| 国产精品妇女一二三区| 国产剧情国产精品一区| 亚洲成色最大综合在线| 色视频综合无码一区二区三区| 果冻传媒18禁免费视频| 搡老岳熟女国产熟妇| 国产做无码视频在线观看浪潮| 精品久久一区二区乱码| 久久亚洲欧美国产精品| 国产成人a人亚洲精v品无码| 色翁荡熄又大又硬又粗又视频图片| 欧美xxxx狂喷水| 国产午精品午夜福利757视频播放| 久久精品日韩av无码| 国产黑色丝袜在线视频| 熟妇人妻中文av无码| 麻豆果冻精东九一传媒mv| 久热爱精品视频线路一 | 在线 | 一区二区三区四区| 四虎国产精品永久在线| 久久人人97超碰国产亚洲人| 丰满少妇人妻hd高清大乳在线 | 夜夜躁很很躁日日躁麻豆| 精品无码久久久久久久久| 久久婷婷国产剧情内射白浆| 亚洲精品无码专区在线播放| 午夜福利三级理论电影| 色窝窝无码一区二区三区| 亚洲精品久久一区二区三区四区| 亚洲国产成人精品无码区四虎| 国产精品成人无码免费| 色综合久久久久无码专区|